In vitro glycoengineering of a monoclonal antibody produced in insect cells
Sugar modifications, in particular, N-glycans, largely determine protein quality, functionality, and, in case of therapeutic biomolecules, safety. Therapeutic monoclonal antibodies (mAbs) generate immune response through effector functions, for which they require complex N-glycans with high levels o...
Main Author: | |
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Other Authors: | , , , , , |
Format: | Master's thesis |
Language: | eng |
Published: |
2024
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Subjects: | |
Online Access: | https://jyx.jyu.fi/handle/123456789/96162 |