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[{"key": "dc.contributor.advisor", "value": "Waller, Katja", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Hyt\u00f6nen, Annika", "language": "", "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2023-03-22T06:29:42Z", "language": null, "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2023-03-22T06:29:42Z", "language": null, "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2023", "language": "", "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/86075", "language": null, "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Sy\u00f6p\u00e4 on Suomen toisiksi yleisin ja maailman yleisin kuolinsyy, ja se on yleistynyt l\u00e4nsimaissa viime vuosikymmenin\u00e4. Yleisimm\u00e4t sy\u00f6v\u00e4t ovat Suomessa rintasy\u00f6p\u00e4 ja eturauhassy\u00f6p\u00e4, joita hoidetaan yleens\u00e4 leikkaushoidolla sek\u00e4 solunsalpaaja- ja/tai s\u00e4dehoidolla. Sy\u00f6p\u00e4hoidot ovat tehokkaita, mutta ne nostavat elimist\u00f6n TNF-a- ja IL-6-pitoisuuksia, mik\u00e4 puolestaan lis\u00e4\u00e4 muun muassa vakavan taudinkuvan riski\u00e4, voimistaa hoitov\u00e4symyst\u00e4 ja heikent\u00e4\u00e4 el\u00e4m\u00e4nlaatua. Liikunta v\u00e4hent\u00e4\u00e4 inflammaatiota ainakin terveill\u00e4 ihmisill\u00e4, joten t\u00e4m\u00e4n kandidaatintutkielman tarkoituksena on selvitt\u00e4\u00e4, voiko liikunta v\u00e4hent\u00e4\u00e4 inflammaatiota sy\u00f6p\u00e4hoitojen aikana.\n \nKatsausta varten suoritettiin tiedonhaku 12.10.2022 Ovid (MEDLINE)- ja CINAHL-tietokantoihin. Hakulauseketta vastaavia artikkeleja l\u00f6ytyi yhteens\u00e4 87, joista 50 poistettiin otsikon ja 24 tiivistelm\u00e4n perusteella. Kolmestatoista j\u00e4ljelle j\u00e4\u00e4neest\u00e4 artikkelista 4 oli duplikaatteja, joiden poiston j\u00e4lkeen yhdeks\u00e4st\u00e4 j\u00e4ljelle j\u00e4\u00e4neest\u00e4 artikkelista kaksi poistettiin koko tekstin perusteella, yksi kontrolliryhm\u00e4n puutteen takia ja yksi huonon laadun vuoksi. Lopulliseen katsaukseen p\u00e4\u00e4tyi siis seitsem\u00e4n artikkelia. \n\nKahdeksasta interventioryhm\u00e4st\u00e4 yhteens\u00e4 kolmessa havaittiin tilastollisesti merkitsev\u00e4 ero IL-6-arvoissa kontrolliryhm\u00e4\u00e4n verrattuna tutkimuksen lopussa. TNF-a-pitoisuuksissa ei havaittu tilastollisesti merkitsevi\u00e4 eroja ryhmien v\u00e4lill\u00e4 yhdess\u00e4k\u00e4\u00e4n tutkimuksessa. Ryhm\u00e4n sis\u00e4ll\u00e4 IL-6-pitoisuudet nousivat kahdeksasta interventioryhm\u00e4st\u00e4 kahdessa tilastollisesti merkitsev\u00e4sti. Seitsem\u00e4st\u00e4 kontrolliryhm\u00e4st\u00e4 puolestaan nelj\u00e4ss\u00e4 ne nousivat tilastollisesti merkitsev\u00e4sti. TNF-a:n osalta vastaavasti seitsem\u00e4st\u00e4 interventioryhm\u00e4st\u00e4 kahdessa ja kuudesta kontrolliryhm\u00e4st\u00e4 yhdess\u00e4 arvot nousivat tilastollisesti merkitsev\u00e4sti.\n\n\nT\u00e4m\u00e4n katsauksen perusteella ei voida vet\u00e4\u00e4 vahvoja johtop\u00e4\u00e4t\u00f6ksi\u00e4, mutta liikunnalla saat-taa olla inflammaatiota v\u00e4hent\u00e4v\u00e4 vaikutus sy\u00f6p\u00e4hoitojen aikana. Katsauksen perusteella liikunta ei ainakaan lis\u00e4\u00e4 inflammaatiota, joten t\u00e4m\u00e4n sek\u00e4 muiden tutkimuksien perusteella liikuntaa voidaan suositella sy\u00f6p\u00e4hoitojen aikana. Lis\u00e4\u00e4 tutkimusta tarvitaan kuitenkin suuremmalla otannalla sek\u00e4 eri n\u00e4k\u00f6kulmista, kuten siit\u00e4, millainen liikunta-annos on optimaalisin sy\u00f6p\u00e4hoitojen aikana, tai miten liikuntamotivaatiota saadaan lis\u00e4tty\u00e4.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by Paivi Vuorio (paelvuor@jyu.fi) on 2023-03-22T06:29:42Z\nNo. of bitstreams: 0", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2023-03-22T06:29:42Z (GMT). No. of bitstreams: 0\n Previous issue date: 2023", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "39", "language": "", "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.language.iso", "value": "fin", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.title", "value": "Liikunnan vaikutukset sytokiinikonsentraatioihin sy\u00f6p\u00e4hoitojen aikana", "language": "", "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", "value": "bachelor thesis", "language": null, "element": "type", "qualifier": null, "schema": "dc"}, {"key": "dc.identifier.urn", "value": "URN:NBN:fi:jyu-202303222225", "language": "", "element": "identifier", "qualifier": "urn", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Bachelor's thesis", "language": "en", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Kandidaatinty\u00f6", "language": "fi", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Liikuntatieteellinen tiedekunta", "language": "fi", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Faculty of Sport and Health Sciences", "language": "en", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Liikunta- ja terveystieteet", "language": "fi", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Sport and Health Sciences", "language": "en", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "Jyv\u00e4skyl\u00e4n yliopisto", "language": "fi", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "University of Jyv\u00e4skyl\u00e4", "language": "en", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Liikuntal\u00e4\u00e4ketiede", "language": "fi", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Sport Medicine", "language": "en", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "yvv.contractresearch.funding", "value": "0", "language": "", "element": "contractresearch", "qualifier": "funding", "schema": "yvv"}, {"key": "dc.type.coar", "value": "http://purl.org/coar/resource_type/c_7a1f", "language": null, "element": "type", "qualifier": "coar", "schema": "dc"}, {"key": "dc.rights.accesslevel", "value": "openAccess", "language": null, "element": "rights", "qualifier": "accesslevel", "schema": "dc"}, {"key": "dc.type.publication", "value": "bachelorThesis", "language": null, "element": "type", "qualifier": "publication", "schema": "dc"}, {"key": "dc.subject.oppiainekoodi", "value": "5042", "language": "", "element": "subject", "qualifier": "oppiainekoodi", "schema": "dc"}, {"key": "dc.subject.yso", "value": "liikunta", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "sy\u00f6p\u00e4taudit", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "sy\u00f6p\u00e4hoidot", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "vaikutukset", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "s\u00e4dehoito", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "leikkaushoito", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "tulehdus", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "hoitomenetelm\u00e4t", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "hoito", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.rights.url", "value": "https://rightsstatements.org/page/InC/1.0/", "language": null, "element": "rights", "qualifier": "url", "schema": "dc"}]
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