Synthesis of 2'-fluorinated-2'-deoxycytidine derivatives to investigate a direct DNA demethylation pathway in stem cells

This master’s thesis is divided into a literature review and an experimental part. The literature review starts with an introduction of nucleic acids and epigenetics, covering both chemical- and biological aspects. These chemical- and biological processes are explained at a level that is needed t...

Full description

Bibliographic Details
Main Author: Ponkkonen, Eveliina
Other Authors: Matemaattis-luonnontieteellinen tiedekunta, Faculty of Sciences, Kemian laitos, Department of Chemistry, University of Jyväskylä, Jyväskylän yliopisto
Format: Master's thesis
Language:eng
Published: 2018
Subjects:
Online Access: https://jyx.jyu.fi/handle/123456789/57848