Synthesis of 2'-fluorinated-2'-deoxycytidine derivatives to investigate a direct DNA demethylation pathway in stem cells
This master’s thesis is divided into a literature review and an experimental part. The literature review starts with an introduction of nucleic acids and epigenetics, covering both chemical- and biological aspects. These chemical- and biological processes are explained at a level that is needed t...
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| Other Authors: | , , , , , |
| Format: | Master's thesis |
| Language: | eng |
| Published: |
2018
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| Subjects: | |
| Online Access: | https://jyx.jyu.fi/handle/123456789/57848 |