Effects of chemotherapy and blocking activin receptor signaling on skeletal muscle size, oxidative capacity and function

Introduction. Doxorubicin (DOX) is widely used as a chemotherapy drug for cancer. However, it is known to affect negatively skeletal muscle mass and function, which can expose to other diseases and decrease survival rate. Presently, there are no accepted drugs for muscle wasting, but myostatin and a...

Full description

Bibliographic Details
Main Author: Poikonen, Aino
Other Authors: Liikuntatieteellinen tiedekunta, Faculty of Sport and Health Sciences, Liikuntabiologian laitos, Department of Biology of Physical Activity, University of Jyväskylä, Jyväskylän yliopisto
Format: Master's thesis
Language:eng
Published: 2016
Subjects:
Online Access: https://jyx.jyu.fi/handle/123456789/50573