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[{"key": "dc.contributor.author", "value": "M\u00e4enp\u00e4\u00e4, Anni", "language": null, "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2013-08-30T03:17:54Z", "language": "", "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2013-08-30T03:17:54Z", "language": "", "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2013", "language": null, "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.other", "value": "oai:jykdok.linneanet.fi:1278734", "language": null, "element": "identifier", "qualifier": "other", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/42048", "language": "", "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Lapsien kuuloaivokuoren kehityst\u00e4 ei ymm\u00e4rret\u00e4 viel\u00e4 hyvin. T\u00e4m\u00e4n tutkielman tarkoitus on selvitt\u00e4\u00e4 kehityksellisi\u00e4 muutoksia my\u00f6h\u00e4isiss\u00e4 magneettisissa kuuloher\u00e4tevasteissa koko p\u00e4\u00e4n kattavalla neuromagnetometrill\u00e4. Tutkimukseen osallistui 6\u201313,5 vuotiaita tyypillisesti kehittyneit\u00e4 lapsia (N = 36), jotka jaettiin kolmeen ik\u00e4ryhm\u00e4\u00e4n, sek\u00e4 aikuisia (N = 11). Osallistujilta mitattiin kuulovasteet yksinkertaisille sini\u00e4\u00e4nille, jonka j\u00e4lkeen lasten vasteita verrattiin aikuisten vasteisiin. \u00c4rsykkeet esitettiin vuorotellen vasempaan ja oikeaan korvaan ja \u00e4rsykkeiden v\u00e4linen aika satunnaistettiin 0,8 ja 1,2 ms:n v\u00e4lill\u00e4.\r\nTutkimustuloksemme osoittaa, ett\u00e4 lasten kuulovasterakenne eroaa huomattavasti aikuisten rakenteesta. Lapsilla vaste muodostui heikosta aktivaatiosta noin 100 ms:ssa sek\u00e4 huomattavasta pitk\u00e4kestoisesta vasteesta noin 250 ms:ssa. Aikuisilla voimakkain aktivaatio oli noin 100 ms:ssa. Kontralateraaliseen korvaan esitetty \u00e4rsyke aiheutti voimakkaamman vasteen kuin ipsilateraaliseen korvaan esitetty \u00e4rsyke sek\u00e4 vasemmalla ett\u00e4 oikealla aivopuoliskolla kaikissa ik\u00e4ryhmiss\u00e4. Lapsilla kontralateraalinen dominanssi n\u00e4kyi sek\u00e4 100 ms:ssa ett\u00e4 250 ms:ssa. Lis\u00e4ksi havaitsimme tutkimuksessamme, ett\u00e4 yksil\u00f6ill\u00e4 oli ep\u00e4symmetrisyytt\u00e4 vasemman ja oikean aivopuoliskon vasteissa aikaisemmassa aikaikkunassa. T\u00e4m\u00e4 viittaa siihen, ett\u00e4 aikuisenkaltainen N100m-vaste ilmestyy aikaisemmin oikealle aivopuoliskolle, kun taas vasemmalla aivopuoliskolla suurimmalla osalla lapsista on viel\u00e4 ep\u00e4kyps\u00e4 P50m-vaste.\r\nMeid\u00e4n tuloksemme osoittavat, ett\u00e4 kuuloaivokuoren toiminta on selv\u00e4sti ep\u00e4kyps\u00e4\u00e4 viel\u00e4 13- vuoden i\u00e4ss\u00e4. Lis\u00e4ksi aikuisilla havaittu kontralateraalisen korvan preferenssi on havaittavissa ainakin kuuden vuoden i\u00e4ss\u00e4. Kyps\u00e4n kuulovasteen ilmestyminen ensin oikealle aivopuoliskolle antaa aihetta olettaa, ett\u00e4 lapsilla oikea kuuloaivokuori kehittyy vasenta nopeammin. T\u00e4m\u00e4 saattaa olla seurausta siit\u00e4, ett\u00e4 vasenta kuuloaivokuorta kuormittaa puhe\u00e4\u00e4nten k\u00e4sittely.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.abstract", "value": "The development of the cortical auditory system is poorly understood in children. This paper examines the maturational changes in the late auditory evoked field studied with whole-head magnetoencephalography (MEG). Neural responses to pure tones were recorded from three groups of typically developing children between 6 and 13.5 years of age (N = 36) and compared with neural responses in adults (N = 11). The stimuli were presented alternately to both ears and the inter-stimulus interval was randomized between 0.8 and 1.2 ms.\r\nOur results indicate that the time course of neural auditory activation differed evidently between children and adults. In children, we detected small activation at around 100 and more prominent long-lasting activation at about 250 ms. In adults, the strongest activation was detected at around 100 ms. The contralateral ear stimulation evoked stronger responses than ipsilateral in the left and right hemisphere in all age groups, and in children this dominance was visible in 100 ms and 250 ms. Further, we detected interindividual asymmetry between hemispheres in children at the earlier time-window suggesting that the adult-like N100m response emerges first in the right hemisphere while in the left hemisphere most of the children had more immature P50m response.\r\nOur results show that the cortical auditory activation is obviously immature still at the age of thirteen. Further, the preference to contralateral ear stimulation detected in adults can be also found in children of at least six years. Finally, the rightward emergence of the mature response type implies that the right auditory cortex matures faster compared to its counterpart in children. This might be due to the demands imposed on the left hemisphere by language processing.", "language": "en", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted using Plone Publishing form by Anni M\u00e4enp\u00e4\u00e4 (anevmaen) on 2013-08-30 03:17:51.888054. Form: Pro gradu -lomake (1 tekij\u00e4) (https://kirjasto.jyu.fi/julkaisut/julkaisulomakkeet/pro-gradu-lomake-1-tekijae). JyX data:", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by jyx lomake-julkaisija (jyx-julkaisija@noreply.fi) on 2013-08-30T03:17:54Z\r\nNo. of bitstreams: 2\r\nURN:NBN:fi:jyu-201308302209.pdf: 4232893 bytes, checksum: b9ef3499fed6698de9a95f463f5a1f01 (MD5)\r\nlicense.html: 107 bytes, checksum: a7d86e598caa500b1b433bbb9dc8ef1c (MD5)", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2013-08-30T03:17:54Z (GMT). No. of bitstreams: 2\r\nURN:NBN:fi:jyu-201308302209.pdf: 4232893 bytes, checksum: b9ef3499fed6698de9a95f463f5a1f01 (MD5)\r\nlicense.html: 107 bytes, checksum: a7d86e598caa500b1b433bbb9dc8ef1c (MD5)\r\n Previous issue date: 2013", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "1 verkkoaineisto.", "language": null, "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.format.mimetype", "value": "application/pdf", "language": null, "element": "format", "qualifier": "mimetype", "schema": "dc"}, {"key": "dc.language.iso", "value": "eng", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.subject.other", "value": "kuuloaivokuori", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "magneettinen kuuloher\u00e4tevaste", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "aivopuoliskojen ep\u00e4symmetrisyys", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "kehitys", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "magnetoenkefalografia", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.title", "value": "Auditory processing in the two hemispheres in developing brain : MEG study", "language": null, "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", "value": "master thesis", "language": null, "element": "type", "qualifier": null, "schema": "dc"}, {"key": "dc.identifier.urn", "value": "URN:NBN:fi:jyu-201308302209", "language": null, "element": "identifier", "qualifier": "urn", "schema": "dc"}, {"key": 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