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[{"key": "dc.contributor.author", "value": "Per\u00e4l\u00e4, Kirsi", "language": null, "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2012-04-17T04:45:35Z", "language": null, "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2012-04-17T04:45:35Z", "language": null, "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2012", "language": null, "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.other", "value": "oai:jykdok.linneanet.fi:1197510", "language": null, "element": "identifier", "qualifier": "other", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/37698", "language": null, "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Taudinaiheuttajat, kuten virukset ovat usein haitallisia is\u00e4nt\u00e4lajilleen. Virusinfektiot voivat heikent\u00e4\u00e4 mm. is\u00e4nt\u00e4lajinsa lis\u00e4\u00e4ntymist\u00e4 ja selviytymist\u00e4, vaikka ne eiv\u00e4t aiheuttaisikaan n\u00e4kyvi\u00e4 oireita is\u00e4nt\u00e4lajeilleen. Jyrsij\u00f6iden yksi yleisimmist\u00e4 viruksista on hantaviruksiin kuuluva Puumala-virus, jonka is\u00e4nt\u00e4laji on mets\u00e4myyr\u00e4 (Myodes glareolus). Hantavirukset ovat RNA-viruksia ja ne levi\u00e4v\u00e4t tehokkaasti tiheiss\u00e4 myyr\u00e4kannoissa. Puumala-virus voi levit\u00e4 mets\u00e4myyrist\u00e4 my\u00f6s ihmisiin hengitysteiden kautta aiheuttaen myyr\u00e4kuumetta. Puumala-viruksen ohella mets\u00e4myyrist\u00e4 on l\u00f6ydetty my\u00f6s lehm\u00e4rokkovirusta, joka on DNA-virus. Lehm\u00e4rokkoviruksen tiedet\u00e4\u00e4n vaikuttavan heikent\u00e4v\u00e4sti mets\u00e4myyrien lis\u00e4\u00e4ntymiseen ja talvella my\u00f6s selviytymiseen. My\u00f6s lehm\u00e4rokkovirus voi tarttua ihmiseen mm. kotikissoilta ihorikkojen kautta aiheuttaen punoittavia rakkuloita ja flunssan kaltaisia oireita ihmisille. Lehm\u00e4rokkovirusinfektio ei ole jyrsij\u00f6ill\u00e4 krooninen, toisin kuin Puumala-virusinfektio, mutta niiden molempien on havaittu olevan haitallisia niiden is\u00e4nt\u00e4lajeilleen, mutta perimm\u00e4isi\u00e4 syit\u00e4 ei viel\u00e4 tiedet\u00e4. Virukset saattavat vaikuttaa is\u00e4nt\u00e4lajin kelpoisuuteen muun muassa niiden metabolian eli aineenvaihdunnan kautta. Metaboliatasoon vaikuttavat mm. yksil\u00f6n ik\u00e4, lis\u00e4\u00e4ntymisvaihe sek\u00e4 muut stressitekij\u00e4t, kuten taudinaiheuttajat. Tutkimuksessa oli tarkoituksena selvitt\u00e4\u00e4 Puumala-viruksen ja lehm\u00e4rokkoviruksen vaikutusta mets\u00e4myyr\u00e4n lepo- ja rasitusmetaboliaan. Mets\u00e4myyr\u00e4populaatiota seurattiin kes\u00e4n 2011 aikana Lammin biologisen aseman l\u00e4heisyydess\u00e4 olevalla mets\u00e4alueella merkint\u00e4-takaisinpyyntimenetelm\u00e4ll\u00e4. Mets\u00e4myyrien lepo- ja rasitusmetaboliamittaukset suoritettiin laboratoriossa respirometrin avulla, joka analysoi myyrien uloshengitysilman CO2-pitoisuuden. Myyrien rasitusmetabolia mitattiin sek\u00e4 juosten ett\u00e4 uiden ja lepometabolia ennen ja j\u00e4lkeen juoksusuorituksen. Myyrilt\u00e4 otettiin verin\u00e4ytteet, mist\u00e4 analysoitiin Puumala-virus- ja lehm\u00e4rokkovirusinfektiot. Puumala-virusinfektoituneita myyri\u00e4 oli 24 kpl ja lehm\u00e4rokkovirusinfektoituneita 21 kpl, kun yhteens\u00e4 62 myyr\u00e4n lepo- ja rasitusmetaboliamittausten tulokset analysoitiin. Puumala-viruksella eik\u00e4 lehm\u00e4rokkoviruksella ollut vaikutusta lepo- ja rasitusmetaboliaan. Koiraiden rasitusmetaboliataso juosten mitattuna oli korkeampi kuin naaraiden ja samansuuntainen trendi oli havaittavissa uiden mitatussa rasitusmetaboliassa. N\u00e4in ollen t\u00e4m\u00e4n tutkimuksen perusteella ei voida sanoa, ett\u00e4 Puumala- tai lehm\u00e4rokkovirusinfektoituneiden korkeampi metaboliataso olisi syyn\u00e4 heikompaan lis\u00e4\u00e4ntymiseen tai selviytymiseen mets\u00e4myyrill\u00e4.", "language": null, "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted using Plone Publishing form by Kirsi Per\u00e4l\u00e4 (kijopera) on 2012-04-17 04:45:34.585409. Form: Pro gradu -lomake (1 tekij\u00e4) (https://kirjasto.jyu.fi/julkaisut/julkaisulomakkeet/pro-gradu-lomake-1-tekijae). JyX data:", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by jyx lomake-julkaisija (jyx-julkaisija@noreply.fi) on 2012-04-17T04:45:34Z\nNo. of bitstreams: 2\nURN:NBN:fi:jyu-201204171541.pdf: 500371 bytes, checksum: 4536f46486facf9533fab40fca27f63c (MD5)\nlicense.html: 5022 bytes, checksum: 31be4e7d91c64c2abd8e8714336f2793 (MD5)", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2012-04-17T04:45:35Z (GMT). No. of bitstreams: 2\nURN:NBN:fi:jyu-201204171541.pdf: 500371 bytes, checksum: 4536f46486facf9533fab40fca27f63c (MD5)\nlicense.html: 5022 bytes, checksum: 31be4e7d91c64c2abd8e8714336f2793 (MD5)\n Previous issue date: 2012", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "22 sivua", "language": null, "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.format.mimetype", "value": "application/pdf", "language": null, "element": "format", "qualifier": "mimetype", "schema": "dc"}, {"key": "dc.language.iso", "value": "fin", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.subject.other", "value": "Lehm\u00e4rokko", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "metaboliataso", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "mets\u00e4myyr\u00e4", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "Puumala-virus", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.title", "value": "Puumala- ja lehm\u00e4rokkoviruksen vaikutus mets\u00e4myyr\u00e4n (Myodes glareolus) metaboliaan", "language": null, "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", "value": "master thesis", "language": null, "element": "type", "qualifier": null, "schema": "dc"}, {"key": "dc.identifier.urn", "value": "URN:NBN:fi:jyu-201204171541", "language": null, "element": "identifier", "qualifier": "urn", "schema": "dc"}, {"key": "dc.type.dcmitype", "value": "Text", "language": "en", "element": "type", "qualifier": "dcmitype", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Pro 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Jyv\u00e4skyl\u00e4", "language": "en", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "Jyv\u00e4skyl\u00e4n yliopisto", "language": "fi", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Ekologia ja evoluutiobiologia", "language": "fi", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Ecology and evolutionary biology", "language": "en", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.date.updated", "value": "2012-04-17T04:45:35Z", "language": null, "element": "date", "qualifier": "updated", "schema": "dc"}, {"key": "dc.type.coar", "value": "http://purl.org/coar/resource_type/c_bdcc", "language": null, "element": "type", "qualifier": "coar", "schema": "dc"}, {"key": "dc.rights.accesslevel", "value": "openAccess", "language": "fi", "element": "rights", 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