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[{"key": "dc.contributor.advisor", "value": "Pekkala, Satu", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Karppinen, Miira", "language": "", "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2024-09-25T06:19:15Z", "language": null, "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2024-09-25T06:19:15Z", "language": null, "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2024", "language": "", "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/97199", "language": null, "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Ei-alkoholiper\u00e4inen rasvamaksa (engl. non-alcoholic fatty liver disease, NAFLD) on nykyisin yleisin maksasairaus l\u00e4nsimaissa. Fyysinen aktiivisuus ja V\u00e4limeren ruokavalio ovat NAFLD:lt\u00e4 suojaavia tekij\u00f6it\u00e4, kun taas liiallinen paikallaanolo, insuliiniresistenssi ja ep\u00e4terveellinen ruokavalio, sis\u00e4lt\u00e4en liiallisen energiansaannin, tyydyttyneiden rasvojen ja sokerin korkean kulutuksen, lis\u00e4\u00e4v\u00e4t NAFLD:n riski\u00e4. V\u00e4hemm\u00e4n tutkimusta on saatavilla korkean glykeemisen indeksin (GI) hiilihydraattien saannin ja NAFLD:n v\u00e4lisest\u00e4 yhteydest\u00e4. T\u00e4m\u00e4n tutkimuksen tarkoituksena oli selvitt\u00e4\u00e4 fyysisen aktiivisuuden, kokonaisenergiansaannin, korkean GI hiilihydraattien saannin ja insuliinisensitiivisyyden/resistenssin sek\u00e4 NAFLD:n v\u00e4lisi\u00e4 yhteyksi\u00e4. Tutkimus toteutettiin poikkileikkaustutkimuksena. Koehenkil\u00f6t olivat 57-78-vuotiaita miehi\u00e4 ja naisia (n=1410) DR\u2019s Extra-tutkimuksesta. Rasvamaksaindeksi\u00e4 (FLI) k\u00e4ytettiin kuvaamaan maksan rasvoittumista. Henkil\u00f6t, joilla oli (aiempi tai nykyinen) hepatiitti tai liiallinen alkoholin k\u00e4ytt\u00f6 (miehet \u226530 g/pv ja naiset \u226520 g/pv, n=577) poissuljettiin analyysista. Fyysist\u00e4 aktiivisuutta mitattiin edellisen 12 kk:n ajalta k\u00e4ytt\u00e4en muokattua versiota Minnesota Leisure Time Physical Activity Questionnaire -kyselylomakkeesta ja ruokavaliota arvioitiin 4 p\u00e4iv\u00e4n ruokap\u00e4iv\u00e4kirjalla. Insuliinisensitiivisyytt\u00e4 mitattiin Matsuda Index of Insulin Sensitivity -indeksill\u00e4 (Matsuda ISI), joka laskettiin sokerirasituskokeen perusteella. Insuliiniresistenssi\u00e4 arvioitiin Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) -menetelm\u00e4ll\u00e4. Tilastolliset analyysit suoritettiin SPSS-ohjelmistolla. Tutkimuksen tulokset ovat saatavilla my\u00f6hemmin julkaistavassa tutkimusartikkelissa.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Non-alcoholic fatty liver disease (NAFLD) is currently the most prevalent liver disease in Western countries. Physical activity (PA) and Mediterranean diet are recognized as protective factors against NAFLD, whereas sedentary behavior, insulin resistance, and poor diet, characterized by an excessive energy intake, high consumption of saturated fats and sugars, increase the risk of NAFLD. However, lesser studies have focused on the association between high glycemic index (GI) carbohydrates and NAFLD. The present study aims to investigate the association between PA, total energy intake, high glycemic index (GI) carbohydrate intake, and insulin sensitivity/resistance with NAFLD. The study was a cross-sectional analysis of 57-78-year-old men and women (n=1410) from DR\u2019s Extra Study. Fatty liver Index (FLI) was used to describe hepatic steatosis. Individuals with (prior or current) hepatitis or excessive alcohol consumption (men\u226530 g/d and women \u226520 g/d, n=577) were excluded from the analysis. PA from previous 12 months was assessed by using modified version of Minnesota Leisure Time Physical Activity Questionnaire and dietary factors were assessed by using a 4-day food diary. Insulin sensitivity was assessed by Matsuda Index of Insulin Sensitivity (Matsuda ISI) that was derived from oral glucose tolerance test (OGTT) with a 75 g of glucose drink. Insulin resistance was assessed by Homeostasis Model Assessment of Insulin Resistance (HOMA-IR). Statistical analyses were performed using the SPSS software. The results of this study will be available later in the forthcoming research article.", "language": "en", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by Paivi Vuorio (paelvuor@jyu.fi) on 2024-09-25T06:19:15Z\nNo. of bitstreams: 0", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2024-09-25T06:19:15Z (GMT). No. of bitstreams: 0\n Previous issue date: 2024", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "82", "language": "", "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.language.iso", "value": "eng", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.subject.other", "value": "ei-alkoholiper\u00e4inen rasvamaksa", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "insuliinisensitiivisyys", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "non-alcoholic fatty liver disease", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "insulin sensitivity", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.title", "value": "The association of physical activity, insulin sensitivity, and dietary factors with hepatic steatosis : a cross-sectional analysis from DR\u2019s EXTRA Study", "language": "", "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", "value": "master thesis", "language": null, "element": "type", "qualifier": null, "schema": "dc"}, {"key": "dc.identifier.urn", "value": "URN:NBN:fi:jyu-202409256075", "language": null, "element": "identifier", "qualifier": "urn", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Master\u2019s thesis", "language": "en", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Pro gradu -tutkielma", "language": "fi", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Liikuntatieteellinen tiedekunta", "language": "fi", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Faculty of Sport and Health Sciences", "language": "en", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Liikunta- ja terveystieteet", "language": "fi", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Sport and Health Sciences", "language": "en", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "Jyv\u00e4skyl\u00e4n yliopisto", "language": "fi", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "University of Jyv\u00e4skyl\u00e4", "language": "en", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Liikuntal\u00e4\u00e4ketiede", "language": "fi", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Sport Medicine", "language": "en", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "yvv.contractresearch.funding", "value": "0", "language": "", "element": "contractresearch", "qualifier": "funding", "schema": "yvv"}, {"key": "dc.type.coar", "value": "http://purl.org/coar/resource_type/c_bdcc", "language": null, "element": "type", "qualifier": "coar", "schema": "dc"}, {"key": "dc.rights.accesslevel", "value": "restrictedAccess", "language": null, "element": "rights", "qualifier": "accesslevel", "schema": "dc"}, {"key": "dc.type.publication", "value": "masterThesis", "language": null, "element": "type", "qualifier": "publication", "schema": "dc"}, {"key": "dc.subject.oppiainekoodi", "value": "5042", "language": "", "element": "subject", "qualifier": "oppiainekoodi", "schema": "dc"}, {"key": "dc.subject.yso", "value": "glykeeminen indeksi", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "energiansaanti", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "rasvamaksa", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "insuliiniresistenssi", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "fyysinen aktiivisuus", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "glycemic index", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "energy intake", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "fatty liver", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "insulin resistance", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "physical activity", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.rights.url", "value": "https://rightsstatements.org/page/InC/1.0/", "language": null, "element": "rights", "qualifier": "url", "schema": "dc"}, {"key": "dc.rights.accessrights", "value": "The author has not given permission to make the work publicly available electronically. Therefore the material can be read only at the archival workstation at Jyv\u00e4skyl\u00e4 University Library (https://kirjasto.jyu.fi/collections/archival-workstation).", "language": "en", "element": "rights", "qualifier": "accessrights", "schema": "dc"}, {"key": "dc.rights.accessrights", "value": "Tekij\u00e4 ei ole antanut lupaa avoimeen julkaisuun, joten aineisto on luettavissa vain Jyv\u00e4skyl\u00e4n yliopiston kirjaston arkistoty\u00f6semalta. Ks. https://kirjasto.jyu.fi/kokoelmat/arkistotyoasema..", "language": "fi", "element": "rights", "qualifier": "accessrights", "schema": "dc"}]
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