Corticospinal Contributions to Neuromuscular Fatigue Following Exausthive Stretch-Shortening Cycle Actions

Neuromuscular fatigue refers to any exercise-induced decline in force generation capacity. It may stem from disturbances in processes at or distal to the neuromuscular junction, referred to as peripheral fatigue, as well as proximal to it, referred to as central fatigue. Central fatigue can be fu...

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Päätekijä: Bascherini, Jacopo
Muut tekijät: Liikuntatieteellinen tiedekunta, Faculty of Sport and Health Sciences, Liikunta- ja terveystieteet, Sport and Health Sciences, Jyväskylän yliopisto, University of Jyväskylä
Aineistotyyppi: Pro gradu
Kieli:eng
Julkaistu: 2024
Aiheet:
Linkit: https://jyx.jyu.fi/handle/123456789/96287
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author Bascherini, Jacopo
author2 Liikuntatieteellinen tiedekunta Faculty of Sport and Health Sciences Liikunta- ja terveystieteet Sport and Health Sciences Jyväskylän yliopisto University of Jyväskylä
author_facet Bascherini, Jacopo Liikuntatieteellinen tiedekunta Faculty of Sport and Health Sciences Liikunta- ja terveystieteet Sport and Health Sciences Jyväskylän yliopisto University of Jyväskylä Bascherini, Jacopo Liikuntatieteellinen tiedekunta Faculty of Sport and Health Sciences Liikunta- ja terveystieteet Sport and Health Sciences Jyväskylän yliopisto University of Jyväskylä
author_sort Bascherini, Jacopo
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description Neuromuscular fatigue refers to any exercise-induced decline in force generation capacity. It may stem from disturbances in processes at or distal to the neuromuscular junction, referred to as peripheral fatigue, as well as proximal to it, referred to as central fatigue. Central fatigue can be further distinguished into spinal or supraspinal fatigue. No studies have assessed central fatigue or the degree of supraspinal fatigue after exhaustive stretch-shortening cycle (SSC) exercise. Therefore, the purpose of the present study was to investigate the acute corticospinal contribution to neuromuscular fatigue following exhaustive SSC exercise. Ten healthy active individuals were assigned to the fatigue group (FAT) and completed the SSC fatigue protocol. Ten different individuals did not engage in any exercise, serving as control group (CON). Maximal voluntary contraction (MVC) and tibial nerve electrical, as well as primary motor cortex magnetic stimulation evoked force and surface EMG (M-wave and MEP) responses, were recorded before and immediately after SSC exercise to assess voluntary activation ratio and corticospinal excitability. To assess the magnitude of acute exercise-induced fatigue, assessments of neuromuscular and corticospinal functions were completed within 3.5 minutes after exercise cessation. Ankle plantar flexor MVC for FAT decreased by ~18.12% (p < 0.001; d = 0.89) after exhaustive SSC exercise. Cortical voluntary activation ratio for FAT declined from 90.3 ± 10.1% at baseline to 77.4 ± 15.4% after SSC exercise (p = 0.001, r = 0.79). Voluntary activation ratio measured via motor nerve stimulation declined from 92.7 ± 6.8% at baseline to 82.3 ± 12.9% after SSC exercise (p = 0.037; r = 0.66). Resting twitch amplitude declined by ~ 9.2% (p = 0.03; d = 0.34). Silent period duration lengthened by ~13.5% (p = 0.01; d = 1.38), while MEPs remained unchanged. Thus, exhaustive SSC exercise induced considerable central fatigue and caused an impairment in the capacity of the motor cortex to drive the ankle plantar flexors along with increased level of intracortical inhibition. As a result, maximum force-generation capacity was significantly reduced by central fatigue as well as by peripheral mechanisms following SSC exercise.
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It \nmay stem from disturbances in processes at or distal to the neuromuscular junction, referred to \nas peripheral fatigue, as well as proximal to it, referred to as central fatigue. Central fatigue can \nbe further distinguished into spinal or supraspinal fatigue. No studies have assessed central \nfatigue or the degree of supraspinal fatigue after exhaustive stretch-shortening cycle (SSC) \nexercise. Therefore, the purpose of the present study was to investigate the acute corticospinal \ncontribution to neuromuscular fatigue following exhaustive SSC exercise. Ten healthy active \nindividuals were assigned to the fatigue group (FAT) and completed the SSC fatigue protocol. \nTen different individuals did not engage in any exercise, serving as control group (CON). \nMaximal voluntary contraction (MVC) and tibial nerve electrical, as well as primary motor \ncortex magnetic stimulation evoked force and surface EMG (M-wave and MEP) responses, \nwere recorded before and immediately after SSC exercise to assess voluntary activation ratio \nand corticospinal excitability. To assess the magnitude of acute exercise-induced fatigue, \nassessments of neuromuscular and corticospinal functions were completed within 3.5 minutes \nafter exercise cessation. Ankle plantar flexor MVC for FAT decreased by ~18.12% (p < 0.001; \nd = 0.89) after exhaustive SSC exercise. Cortical voluntary activation ratio for FAT declined \nfrom 90.3 \u00b1 10.1% at baseline to 77.4 \u00b1 15.4% after SSC exercise (p = 0.001, r = 0.79). \nVoluntary activation ratio measured via motor nerve stimulation declined from 92.7 \u00b1 6.8% at \nbaseline to 82.3 \u00b1 12.9% after SSC exercise (p = 0.037; r = 0.66). Resting twitch amplitude \ndeclined by ~ 9.2% (p = 0.03; d = 0.34). Silent period duration lengthened by ~13.5% (p = 0.01; \nd = 1.38), while MEPs remained unchanged. Thus, exhaustive SSC exercise induced \nconsiderable central fatigue and caused an impairment in the capacity of the motor cortex to \ndrive the ankle plantar flexors along with increased level of intracortical inhibition. 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spellingShingle Bascherini, Jacopo Corticospinal Contributions to Neuromuscular Fatigue Following Exausthive Stretch-Shortening Cycle Actions Neuromuscular Fatigue Central Fatigue Voluntary Activation Stretch-Shortening Cycle Ankle Plantar Flexors Biomekaniikka Biomechanics 5012 lihakset motoriikka väsymys muscles motor functions fatigue (biological phenomena)
title Corticospinal Contributions to Neuromuscular Fatigue Following Exausthive Stretch-Shortening Cycle Actions
title_full Corticospinal Contributions to Neuromuscular Fatigue Following Exausthive Stretch-Shortening Cycle Actions
title_fullStr Corticospinal Contributions to Neuromuscular Fatigue Following Exausthive Stretch-Shortening Cycle Actions Corticospinal Contributions to Neuromuscular Fatigue Following Exausthive Stretch-Shortening Cycle Actions
title_full_unstemmed Corticospinal Contributions to Neuromuscular Fatigue Following Exausthive Stretch-Shortening Cycle Actions Corticospinal Contributions to Neuromuscular Fatigue Following Exausthive Stretch-Shortening Cycle Actions
title_short Corticospinal Contributions to Neuromuscular Fatigue Following Exausthive Stretch-Shortening Cycle Actions
title_sort corticospinal contributions to neuromuscular fatigue following exausthive stretch shortening cycle actions
title_txtP Corticospinal Contributions to Neuromuscular Fatigue Following Exausthive Stretch-Shortening Cycle Actions
topic Neuromuscular Fatigue Central Fatigue Voluntary Activation Stretch-Shortening Cycle Ankle Plantar Flexors Biomekaniikka Biomechanics 5012 lihakset motoriikka väsymys muscles motor functions fatigue (biological phenomena)
topic_facet 5012 Ankle Plantar Flexors Biomechanics Biomekaniikka Central Fatigue Neuromuscular Fatigue Stretch-Shortening Cycle Voluntary Activation fatigue (biological phenomena) lihakset motor functions motoriikka muscles väsymys
url https://jyx.jyu.fi/handle/123456789/96287 http://www.urn.fi/URN:NBN:fi:jyu-202407035115
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