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[{"key": "dc.contributor.advisor", "value": "Hielm-bj\u00f6rkman, Anna", "language": null, "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.advisor", "value": "Yl\u00e4nne, Jari", "language": null, "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Tukonen, Laura", "language": "", "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2024-06-14T11:03:17Z", "language": null, "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2024-06-14T11:03:17Z", "language": null, "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2024", "language": null, "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/95892", "language": null, "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Because incidence of diabetes mellitus in dog has increased, easy and efficient \nglucose monitoring techniques are needed. Saliva sampling offers a \nstraightforward and non-invasive method for measuring glucose levels in dogs, \nproviding a unique way to study disease markers. The low \u03b1-amylase levels in \ncanine saliva ensure stable glucose measurements without the need for invasive \nprocedures. This thesis aims to evaluate the effectiveness of the prototype 2 saliva \nglucose test for monitoring glucose levels in dogs. We compared the saliva test \nresults to simultaneous traditional blood and urine glucose tests and to continue \nmonitoring of interstitial glucose level with a skin-attached electronic device. \nAdditionally, the owners of the dogs gave feedback on the tests\u2019 usability. The \nPrototype 2 saliva glucose test showed a 71.3% accuracy in a study of 164 samples,\nwith 80.5% sensitivity and 66.6% specificity. Moreover, the saliva test \ndemonstrated moderate discriminative ability, with an Area Under Curve (AUC) \nvalue of 0.708. The dogs\u2019 owners feedback revealed high satisfaction with the \ntests\u2019 non-invasive nature and easy use. The Prototype 2 saliva glucose test has the \npotential to significantly improve canine diabetes management by offering a less \nstressful and more accessible monitoring option for pet owners. But this test still \nneeds further development.", "language": "en", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Koska diabeteksen esiintyvyys koirilla on kasvanut, tarvitaan helppoja ja\ntehokkaita glukoosin seurantamenetelmi\u00e4. Sylkin\u00e4ytteiden ottaminen tarjoaa\nsuoran ja ei-invasiivisen menetelm\u00e4n glukoosipitoisuuksien mittaamiseen\nkoirilla, mahdollistaen taudin merkkiaineiden tutkimisen. Koiran syljen matalat\n\u03b1-amylaasipitoisuudet takaavat stabiilit glukoosimittaukset ilman invasiivisia\ntoimenpiteit\u00e4. T\u00e4ss\u00e4 tutkielmassa arvioitiin prototyypin 2 sylkiglukoositestin\ntehokkuutta koirien glukoosipitoisuuksien seurannassa. Vertasimme sylkitestin\ntuloksia samanaikaisiin perinteisiin veren ja virtsan glukoositesteihin sek\u00e4\njatkuvaa solunesteen glukoosipitoisuuden seurantaa ihoon kiinnitetyll\u00e4\nelektronisella laitteella. Lis\u00e4ksi koirien omistajilta ker\u00e4ttiin palautetta testin\nk\u00e4ytett\u00e4vyydest\u00e4. Prototyypin 2 sylkiglukoositesti osoitti 71,3 % tarkkuuden\ntutkimuksessa, jossa otettiin 164 testi\u00e4. Testill\u00e4 oli 80,5 % herkkyys ja 66,6 %\nspesifisyys 10 koiran otoksessa (viisi diabeetikkoa ja viisi tervett\u00e4 koiraa). Vaikka\ntestin diskriminointikyky oli kohtalainen (AUC 0,708), koirien omistajien antama\npalaute korostaa sen potentiaalia helpottaa koirien diabeteksen hallintaa. On\nkuitenkin selv\u00e4\u00e4, ett\u00e4 testi tarvitsee viel\u00e4 lis\u00e4kehityst\u00e4.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by Miia Hakanen (mihakane@jyu.fi) on 2024-06-14T11:03:17Z\nNo. of bitstreams: 0", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2024-06-14T11:03:17Z (GMT). No. of bitstreams: 0\n Previous issue date: 2024", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "47", "language": "", "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.language.iso", "value": "eng", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.title", "value": "Saliva glucose test in canine diabetes monitoring", "language": "", "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", "value": "master thesis", "language": null, "element": "type", "qualifier": null, "schema": "dc"}, {"key": "dc.identifier.urn", "value": "URN:NBN:fi:jyu-202406144658", "language": null, "element": "identifier", "qualifier": "urn", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Master\u2019s thesis", "language": "en", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Pro gradu -tutkielma", "language": "fi", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Faculty of Sciences", "language": "en", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Matemaattis-luonnontieteellinen tiedekunta", "language": "fi", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Department of Biological and Environmental Science", "language": "en", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Bio- ja ymp\u00e4rist\u00f6tieteiden laitos", "language": "fi", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "University of Jyv\u00e4skyl\u00e4", "language": "en", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "Jyv\u00e4skyl\u00e4n yliopisto", "language": "fi", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Cell and molecular biology", "language": "en", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Solu- ja molekyylibiologia", "language": "fi", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "yvv.contractresearch.funding", "value": "0", "language": "", "element": "contractresearch", "qualifier": "funding", "schema": "yvv"}, {"key": "yvv.contractresearch.initiative", "value": "business", "language": "", "element": "contractresearch", "qualifier": "initiative", "schema": "yvv"}, {"key": "dc.type.coar", "value": "http://purl.org/coar/resource_type/c_bdcc", "language": null, "element": "type", "qualifier": "coar", "schema": "dc"}, {"key": "dc.rights.accesslevel", "value": "openAccess", "language": null, "element": "rights", "qualifier": "accesslevel", "schema": "dc"}, {"key": "dc.type.publication", "value": "masterThesis", "language": null, "element": "type", "qualifier": "publication", "schema": "dc"}, {"key": "dc.subject.oppiainekoodi", "value": "4013", "language": null, "element": "subject", "qualifier": "oppiainekoodi", "schema": "dc"}, {"key": "dc.subject.yso", "value": "glukoosi", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "koira", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "diabetes", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "sylki", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "mittaus", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "testaus", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "mittausmenetelm\u00e4t", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "diagnostiikka", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "glucose", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "dog", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "diabetes", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "saliva", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "measurement", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "testing", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "measuring methods", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "diagnostics", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.rights.url", "value": "https://rightsstatements.org/page/InC/1.0/", "language": null, "element": "rights", "qualifier": "url", "schema": "dc"}]
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