Thumb carpometacarpal joint osteoarthritis current treatment practice and a cross-over pilot study

Peukalon tyvinivelen nivelrikko on yleisin käden alueen rappeumaperäinen sairaus. Esiintyvyys lisääntyy iän myötä ja peukalon tyvinivelen nivelrikko vaikuttaa laajalti käden käyttöön päivittäisissä toimissa. Tämän tutkielman tarkoituksena on tehdä systemaattinen kirjallisuushaku peukalo-ortoosin vai...

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Main Author: Jaatinen, Kati
Other Authors: Faculty of Sport and Health Sciences, Liikuntatieteellinen tiedekunta, Sport and Health Sciences, Liikunta- ja terveystieteet, University of Jyväskylä, Jyväskylän yliopisto
Format: Master's thesis
Language:eng
Published: 2024
Subjects:
Online Access: https://jyx.jyu.fi/handle/123456789/92978
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author Jaatinen, Kati
author2 Faculty of Sport and Health Sciences Liikuntatieteellinen tiedekunta Sport and Health Sciences Liikunta- ja terveystieteet University of Jyväskylä Jyväskylän yliopisto
author_facet Jaatinen, Kati Faculty of Sport and Health Sciences Liikuntatieteellinen tiedekunta Sport and Health Sciences Liikunta- ja terveystieteet University of Jyväskylä Jyväskylän yliopisto Jaatinen, Kati Faculty of Sport and Health Sciences Liikuntatieteellinen tiedekunta Sport and Health Sciences Liikunta- ja terveystieteet University of Jyväskylä Jyväskylän yliopisto
author_sort Jaatinen, Kati
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description Peukalon tyvinivelen nivelrikko on yleisin käden alueen rappeumaperäinen sairaus. Esiintyvyys lisääntyy iän myötä ja peukalon tyvinivelen nivelrikko vaikuttaa laajalti käden käyttöön päivittäisissä toimissa. Tämän tutkielman tarkoituksena on tehdä systemaattinen kirjallisuushaku peukalo-ortoosin vaikutuksesta käden toimintaan ja kipuun sekä pilottitutkimuksen avulla verrata peukalo-ortoosin ja ison monikulmaluun poiston välistä vaikutusta käden toimintaan ja kipuun ihmisillä, joilla on peukalon tyvinivelen nivelrikko. Kansainvälisen toimintakyvyn, toimintarajoitteiden ja terveyden luokituksen (ICF) viitekehyksessä tarkasteltuna nivelrikkomuutokset peukalon tyvinivelessä vaikuttavat peukalon liikkuvuuteen, käden voimantuottoon ja aiheuttavat kipua. Muutokset vaikeuttavat päivittäisiä toimia, joissa tartutaan, puristetaan tai käännetään esineitä. Yksilön osallistuminen työelämään ja harrastuksiin, sekä selviäminen kotona voivat hankaloitua. Ympäristöllä ja yksilöllisillä tekijöillä on merkitystä siinä, kuinka haittaavaksi käden toiminnan rajoitteet ja kipu koetaan. Kansainvälisten hoitosuositusten mukaisesti alkuvaiheen hoito on konservatiivinen. Jos lääkehoito, ohjaus ja neuvonta, kuntouttavat harjoitteet, tuet ja apuvälineet eivät tuo riittävää helpotusta oireisiin, on kirurgisella hoidolla mahdollista lievittää oireita. Tieteellinen näyttö sekä konservatiivisen että kirurgisen hoidon vaikuttavuudesta on kuitenkin puutteellista. Systemaattinen kirjallisuushaku toteutettiin kolmeen tietokantaan. Haussa löytyi seitsemän satunnaistettua ja kontrolloitua tutkimusta, joissa verrattiin peukalo-ortoosin vaikutusta kontrolliryhmään, joka ei saanut hoitoa tai sai muuta, normaalin hoitokäytännön mukaista vähäistä hoitoa. Tutkimusten metodologinen laatu arvioitiin Cochrane risk-of-bias 1 (RoB 1) työkalulla. Metodologinen laatu oli heikko ja tulokset olivat osin ristiriitaisia. Kirjallisuuden perusteella näyttää siltä, että peukalo-ortoosilla saattaa olla vaikutusta käden toimintaan ja kipuun alle kolmen kuukauden ja alle vuoden seurannassa. Vaikutus ei kuitenkaan ole kliinisesti merkittävä. Pilottitutkimuksessa osallistujat käyttivät peukalo-ortoosia kuusi viikkoa ennen kirurgista hoitoa, jonka jälkeen käden toimintakykyä ja kipuoireita seurattiin vuoden ajan. Pilottitutkimuksen tulos oli peukalo-ortoosin osalta samankaltainen kuin aiemmissa tutkimuksissa. Kuuden viikon seurannassa kolmasosa osallistujista koki toimintakykynsä tai peukalon kivun parantuneen. Vuoden seurannassa kirurgisen hoidon vaikutus oli moninkertainen, mutta paraneminen vei osallistujilta 3-6 kuukautta. Näyttö sekä konservatiivisen että kirurgisen hoidon vaikuttavuudesta on puutteellista ja kirjallisuuden perusteella näyttää siltä, että osa ihmisistä pärjää peukalon tyvinivelen nivelrikon oireiden kanssa ilman leikkaushoitoa. Tämän vuoksi tarvitaan lisää hyvälaatuisia satunnaistettuja tutkimuksia, joissa verrataan sekä konservatiivista että kirurgista hoitoa ryhmään, joka ei saa hoitoa. The thumb carpometacarpal joint osteoarthritis is the most prevalent degenerative disease affecting the hand region. Its prevalence increases with age, and the thumb carpometacarpal joint osteoarthritis significantly affects hand usage in daily activities. The purpose of this master’s thesis is to perform a systematic literature review of the effect of the thumb orthosis and compare the effect of thumb orthosis and trapeziectomy on hand function and pain in individuals with thumb carpometacarpal joint osteoarthritis in a pilot study. In the context of the International Classification of Functioning, Disability, and Health (ICF) framework, osteoarthritic changes in the basal joint of the thumb impact thumb mobility, hand strength, and induce pain. Daily activities involving grasping, gripping, and rotating objects may become challenging. An individual’s participation in hobbies or work, as well as managing tasks at home, may be compromised. The perceived impact of hand function limitations and pain is influenced by environmental and individual factors. In accordance with international treatment guidelines, initial management is conservative. If pharmacotherapy, patient education, rehabilitative exercises, orthosis, and assistive devices fail to provide sufficient relief from symptoms, surgical intervention may alleviate symptoms. However, there is a lack of scientific evidence regarding the efficacy of both conservative and surgical treatments. A systematic literature review was conducted in three databases. Seven randomized controlled trials comparing the effect of thumb orthosis to a control group with no intervention or usual care were identified. The methodological quality of the studies was evaluated with Cochrane risk-of-bias 1 (RoB 1) tool. The methodological quality was low, and the results were partially contradictory. Based on the literature, it appears that a thumb orthosis may have an effect on hand function and pain within a follow-up period of under three months to under one year. However, this effect is not clinically significant. In the pilot study, participants used a thumb orthosis for six weeks prior to undergoing surgical treatment. Hand's functional capacity and pain symptoms were monitored for one year after the surgical treatment. The result of the pilot study regarding the thumb orthosis is similar to previous literature. At a six-week follow-up, one third of participants reported improved function or reduced thumb pain. At the one-year follow-up, the effect of surgical intervention was manifold, but recovery took 3 to 6 months. Evidence regarding the effect of both conservative and surgical treatments is insufficient. Based on the literature, it seems that some individuals can manage symptoms of thumb carpometacarpal joint osteoarthritis without surgical intervention. Therefore, additional high-quality randomized trials comparing both conservative and surgical treatment to a no-treatment are needed.
first_indexed 2024-01-23T21:00:57Z
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Esiintyvyys lis\u00e4\u00e4ntyy i\u00e4n my\u00f6t\u00e4 ja peukalon tyvinivelen nivelrikko vaikuttaa laajalti k\u00e4den k\u00e4ytt\u00f6\u00f6n p\u00e4ivitt\u00e4isiss\u00e4 toimissa. T\u00e4m\u00e4n tutkielman tarkoituksena on tehd\u00e4 systemaattinen kirjallisuushaku peukalo-ortoosin vaikutuksesta k\u00e4den toimintaan ja kipuun sek\u00e4 pilottitutkimuksen avulla verrata peukalo-ortoosin ja ison monikulmaluun poiston v\u00e4list\u00e4 vaikutusta k\u00e4den toimintaan ja kipuun ihmisill\u00e4, joilla on peukalon tyvinivelen nivelrikko.\n\nKansainv\u00e4lisen toimintakyvyn, toimintarajoitteiden ja terveyden luokituksen (ICF) viitekehyksess\u00e4 tarkasteltuna nivelrikkomuutokset peukalon tyviniveless\u00e4 vaikuttavat peukalon liikkuvuuteen, k\u00e4den voimantuottoon ja aiheuttavat kipua. Muutokset vaikeuttavat p\u00e4ivitt\u00e4isi\u00e4 toimia, joissa tartutaan, puristetaan tai k\u00e4\u00e4nnet\u00e4\u00e4n esineit\u00e4. Yksil\u00f6n osallistuminen ty\u00f6el\u00e4m\u00e4\u00e4n ja harrastuksiin, sek\u00e4 selvi\u00e4minen kotona voivat hankaloitua. Ymp\u00e4rist\u00f6ll\u00e4 ja yksil\u00f6llisill\u00e4 tekij\u00f6ill\u00e4 on merkityst\u00e4 siin\u00e4, kuinka haittaavaksi k\u00e4den toiminnan rajoitteet ja kipu koetaan. Kansainv\u00e4listen hoitosuositusten mukaisesti alkuvaiheen hoito on konservatiivinen. Jos l\u00e4\u00e4kehoito, ohjaus ja neuvonta, kuntouttavat harjoitteet, tuet ja apuv\u00e4lineet eiv\u00e4t tuo riitt\u00e4v\u00e4\u00e4 helpotusta oireisiin, on kirurgisella hoidolla mahdollista lievitt\u00e4\u00e4 oireita. Tieteellinen n\u00e4ytt\u00f6 sek\u00e4 konservatiivisen ett\u00e4 kirurgisen hoidon vaikuttavuudesta on kuitenkin puutteellista.\n\nSystemaattinen kirjallisuushaku toteutettiin kolmeen tietokantaan. Haussa l\u00f6ytyi seitsem\u00e4n satunnaistettua ja kontrolloitua tutkimusta, joissa verrattiin peukalo-ortoosin vaikutusta kontrolliryhm\u00e4\u00e4n, joka ei saanut hoitoa tai sai muuta, normaalin hoitok\u00e4yt\u00e4nn\u00f6n mukaista v\u00e4h\u00e4ist\u00e4 hoitoa. Tutkimusten metodologinen laatu arvioitiin Cochrane risk-of-bias 1 (RoB 1) ty\u00f6kalulla. Metodologinen laatu oli heikko ja tulokset olivat osin ristiriitaisia. Kirjallisuuden perusteella n\u00e4ytt\u00e4\u00e4 silt\u00e4, ett\u00e4 peukalo-ortoosilla saattaa olla vaikutusta k\u00e4den toimintaan ja kipuun alle kolmen kuukauden ja alle vuoden seurannassa. Vaikutus ei kuitenkaan ole kliinisesti merkitt\u00e4v\u00e4.\n\nPilottitutkimuksessa osallistujat k\u00e4yttiv\u00e4t peukalo-ortoosia kuusi viikkoa ennen kirurgista hoitoa, jonka j\u00e4lkeen k\u00e4den toimintakyky\u00e4 ja kipuoireita seurattiin vuoden ajan. Pilottitutkimuksen tulos oli peukalo-ortoosin osalta samankaltainen kuin aiemmissa tutkimuksissa. Kuuden viikon seurannassa kolmasosa osallistujista koki toimintakykyns\u00e4 tai peukalon kivun parantuneen. Vuoden seurannassa kirurgisen hoidon vaikutus oli moninkertainen, mutta paraneminen vei osallistujilta 3-6 kuukautta. N\u00e4ytt\u00f6 sek\u00e4 konservatiivisen ett\u00e4 kirurgisen hoidon vaikuttavuudesta on puutteellista ja kirjallisuuden perusteella n\u00e4ytt\u00e4\u00e4 silt\u00e4, ett\u00e4 osa ihmisist\u00e4 p\u00e4rj\u00e4\u00e4 peukalon tyvinivelen nivelrikon oireiden kanssa ilman leikkaushoitoa. T\u00e4m\u00e4n vuoksi tarvitaan lis\u00e4\u00e4 hyv\u00e4laatuisia satunnaistettuja tutkimuksia, joissa verrataan sek\u00e4 konservatiivista ett\u00e4 kirurgista hoitoa ryhm\u00e4\u00e4n, joka ei saa hoitoa.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.abstract", "value": "The thumb carpometacarpal joint osteoarthritis is the most prevalent degenerative disease affecting the hand region. Its prevalence increases with age, and the thumb carpometacarpal joint osteoarthritis significantly affects hand usage in daily activities. The purpose of this master\u2019s thesis is to perform a systematic literature review of the effect of the thumb orthosis and compare the effect of thumb orthosis and trapeziectomy on hand function and pain in individuals with thumb carpometacarpal joint osteoarthritis in a pilot study.\n\nIn the context of the International Classification of Functioning, Disability, and Health (ICF) framework, osteoarthritic changes in the basal joint of the thumb impact thumb mobility, hand strength, and induce pain. Daily activities involving grasping, gripping, and rotating objects may become challenging. An individual\u2019s participation in hobbies or work, as well as managing tasks at home, may be compromised. The perceived impact of hand function limitations and pain is influenced by environmental and individual factors. 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spellingShingle Jaatinen, Kati Thumb carpometacarpal joint osteoarthritis : current treatment practice and a cross-over pilot study thumb basal joint carpometacarpal joint orthosis conservative treatment surgical treatment effectiveness Physiotherapy Fysioterapia 50422 nivelrikko leikkaushoito fysioterapia kipu interventiohoito vaikutukset arthrosis physiotherapy pain intervention (treatment methods) effects (results)
title Thumb carpometacarpal joint osteoarthritis : current treatment practice and a cross-over pilot study
title_full Thumb carpometacarpal joint osteoarthritis : current treatment practice and a cross-over pilot study
title_fullStr Thumb carpometacarpal joint osteoarthritis : current treatment practice and a cross-over pilot study Thumb carpometacarpal joint osteoarthritis : current treatment practice and a cross-over pilot study
title_full_unstemmed Thumb carpometacarpal joint osteoarthritis : current treatment practice and a cross-over pilot study Thumb carpometacarpal joint osteoarthritis : current treatment practice and a cross-over pilot study
title_short Thumb carpometacarpal joint osteoarthritis
title_sort thumb carpometacarpal joint osteoarthritis current treatment practice and a cross over pilot study
title_sub current treatment practice and a cross-over pilot study
title_txtP Thumb carpometacarpal joint osteoarthritis : current treatment practice and a cross-over pilot study
topic thumb basal joint carpometacarpal joint orthosis conservative treatment surgical treatment effectiveness Physiotherapy Fysioterapia 50422 nivelrikko leikkaushoito fysioterapia kipu interventiohoito vaikutukset arthrosis physiotherapy pain intervention (treatment methods) effects (results)
topic_facet 50422 Fysioterapia Physiotherapy arthrosis basal joint carpometacarpal joint conservative treatment effectiveness effects (results) fysioterapia interventiohoito intervention (treatment methods) kipu leikkaushoito nivelrikko orthosis pain physiotherapy surgical treatment thumb vaikutukset
url https://jyx.jyu.fi/handle/123456789/92978 http://www.urn.fi/URN:NBN:fi:jyu-202401231469
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