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[{"key": "dc.contributor.advisor", "value": "Hautala, Arto", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Ventovuori, Ville", "language": "", "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2023-06-06T04:50:18Z", "language": null, "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2023-06-06T04:50:18Z", "language": null, "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2023", "language": "", "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/87447", "language": null, "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "S\u00e4\u00e4nn\u00f6llinen tavoitteellinen harjoittelu voi aiheuttaa urheilijoille syd\u00e4nlihaksen adaptaatioita ja muutoksia, joita kuvataan termill\u00e4 \u201durheilijansyd\u00e4n\u201d. Jatkuva kovatehoinen harjoittelu voi aiheuttaa kohonneen kammioiden paineylikuormituksen johdosta syd\u00e4nlihaksen muutoksia. Syd\u00e4nlihakseen voi synty\u00e4 t\u00e4m\u00e4n johdosta mikroskooppisia vaurioita, jotka voivat johtaa syd\u00e4nlihaksen fibroosiin (SF). SF m\u00e4\u00e4ritell\u00e4\u00e4n kollageenisen arpikudoksen lis\u00e4\u00e4ntyneeksi m\u00e4\u00e4r\u00e4ksi syd\u00e4mess\u00e4 ja sen on osoitettu lis\u00e4\u00e4v\u00e4n riski\u00e4 haitallisiin syd\u00e4nper\u00e4isiin ongelmiin.\n\nSyd\u00e4ns\u00e4hk\u00f6k\u00e4yr\u00e4\u00e4 (elektrokardiografia, EKG) analysoimalla on tunnistettu muuttujia, joita on yhdistetty SF:n. Urheilijoita ei ole aikaisemmin tutkittu tai vertailtu n\u00e4iden SF:n EKG-muuttujien osalta. T\u00e4ss\u00e4 tutkimuksessa analysoimme aikuisyleisurheilijoiden (n=155) 12-kytkent\u00e4isi\u00e4 lepo-EKG:it\u00e4. Urheilijat olivat i\u00e4lt\u00e4\u00e4n keskim\u00e4\u00e4rin 61\u00b117\u2013vuotiaita ja heill\u00e4 oli taustalla noin 28\u00b118 vuotta harjoittelua yleisurheilulajeista. Analyysit toteutettiin kolmessa lajiryhm\u00e4ss\u00e4 (kest\u00e4vyysurheilijat n=51, 22 naista, lyhyen matkan juoksijat n=69, 25 naista ja heitt\u00e4j\u00e4t ja hypp\u00e4\u00e4j\u00e4t n=35, 18 naista) sek\u00e4 erikseen sukupuolen mukaan. Lepo-EKG:n perusmuuttujien lis\u00e4ksi analysoimme potentiaalisia SF:n EKG-muuttujia (T-aallon inversio, pirstoutunut QRS-kompleksi (fQRS), pidentynyt QRS-kompleksi sek\u00e4 patologinen Q-aalto).\n\nKest\u00e4vyysurheilijoilla oli matalampi leposyke (54\u00b18 ly\u00f6nti\u00e4 minuutissa, bpm) verrattuna lyhyen matkan juoksijoihin (63\u00b112 bpm) ja heitt\u00e4jiin ja hypp\u00e4\u00e4jiin (62\u00b112 bpm) (p<0.001). Leposyke jakautui samalla tavalla, kun miehi\u00e4 ja naisia verrattiin erikseen lajiryhmitt\u00e4in (miehet p<0.001, naiset p=0.017). Er\u00e4iss\u00e4 EKG-perusmuuttujissa havaittiin eroja lajiryhmien v\u00e4lill\u00e4. Esimerkiksi kest\u00e4vyysurheilijoilla oli keskiarvoltaan pidemm\u00e4t QT-ajat (448\u00b137 ms), kuin lyhyen matkan juoksijoilla (413\u00b133 ms) ja heitt\u00e4jill\u00e4 ja hypp\u00e4\u00e4jill\u00e4 (417\u00b139 ms) (p<0.001), mutta sykekorjattua Bazettin kaavaa k\u00e4ytt\u00e4en lajiryhm\u00e4t eiv\u00e4t poikenneet toisistaan (p=0.815). Kest\u00e4vyysurheilijoilla oli my\u00f6s pidempi PR-aika (176\u00b125 ms) verrattuna lyhyen matkan juoksijoihin (169\u00b134 ms) ja heitt\u00e4jiin ja hypp\u00e4\u00e4jiin (164\u00b121 ms) (p=0.046). SF:a kuvaavien EKG-muuttujien esiintyvyys vaihteli 3% (pidentynyt QRS-kompleksi) ja 32% (fQRS) v\u00e4lill\u00e4. Selvi\u00e4 eroja SF:n EKG-muuttujissa ei havaittu lajiryhmien tai sukupuolten v\u00e4lill\u00e4. Esimerkiksi fQRS:n esiintyvyys oli kest\u00e4vyysurheilijoilla 29% (n=15), lyhyen matkan juoksijoilla 34% (n=24) ja heitt\u00e4jill\u00e4 ja hypp\u00e4\u00e4jill\u00e4 29% (n=10). Samanlainen fQRS:n esiintyvyys havaittiin, kun lajiryhmi\u00e4 verrattiin sukupuolten kesken, jolloin fQRS:n esiintyvyys vaihteli 24% ja 38% v\u00e4lill\u00e4. \n\nSF:a kuvaavia EKG-muuttujia havaittiin aikuisyleisurheilijoilla urheilulajista ja sukupuolesta riippumatta. SF:n EKG-muuttujia voidaan mahdollisesti k\u00e4ytt\u00e4\u00e4 SF:n aikaiseen havaitsemiseen. SF:a kuvaavien EKG-muuttujien esiintyvyydest\u00e4 ja vaikutuksesta tarvitaan kuitenkin lis\u00e4\u00e4 tutkimuksia, sill\u00e4 niiden yhteydest\u00e4 urheilijan syd\u00e4nterveyteen ei ole riitt\u00e4v\u00e4sti tietoa.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Regular exercise training produces cardiovascular adaptations and cardiac remodeling for athletes. These changes are referred with the term \u201cathlete\u2019s heart\u201d. The high amount of training in frequency and intensity may lead to pressure and volume overload changes in ventricles and myocardium. The pressure overload can in time cause slow and adaptative damage in myocardial tissue, which can lead to myocardial fibrosis (MF). MF is usually defined as an increased quantity of collagenous scar tissue in the heart which has been shown to be associated with adverse cardiac events.\nCertain markers of electrocardiography (ECG) have shown to be associated with the presence of MF. Since athletes have not been studied with these markers, we analyzed the 12-lead resting ECG\u2019s from 155 track-and-field masters athletes (61\u00b117 years old) with 28\u00b118 years of training background, in three sports specific groups (endurance athletes n=51, 22 females, sprinters n=69, 25 females and throwers & jumpers \u201cT&J\u201d n=35, 18 females) and in biological sex. In addition to analysis of main components of the 12-lead resting ECG, we conducted analysis for potential MF related ECG markers such as T wave inversion (TWI), fragmented QRS complex (fQRS), prolonged QRS complex and pathological Q waves.\nEndurance athletes had lower resting heart rates (54\u00b18 bpm) compared to sprinters (63\u00b112 bpm) and T&J athletes (62\u00b112 bpm) (p<0.001). Similar findings were seen when males (p<0.001) and females (p=0.017) were analyzed separately in sport specific groups. Some differences were observed in ECG parameters such as longer QT interval durations (ms) for endurance athletes (448\u00b137 ms) compared to sprinters (413\u00b133 ms) and T&J group (417\u00b139 ms) (p<0.001), but not after Bazett\u2019s corrected QT interval (p=0.815). Endurance athletes showed also longer PR intervals (176\u00b125 ms) compared to sprinters (169\u00b134 ms) and T&J athletes (164\u00b121 ms) (p=0.046). The prevalence of potential MF connected ECG markers varied between 3% (prolonged QRS) to 32% (fQRS) without no clear difference between sport groups and genders. For example, the prevalence of fQRS for endurance athletes was 29% (n=15), 34% for sprinters (n=24) and 29% for T&J (n=10). Similar prevalence of fQRS was seen when the athlete groups were compared between genders varying from 24% to 38%\nPotential MF related ECG markers were recognized among masters athletes independent of sports specificity and gender. The results may provide a potentially useful non-invasive method for early recognition of MF in athletes hearts. More research is needed to substantiate our findings and corroborate them statistically, and also to elucidate the relevance of MF related ECG markers for athletes\u2019 cardiac health.", "language": "en", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by Miia Hakanen (mihakane@jyu.fi) on 2023-06-06T04:50:18Z\nNo. of bitstreams: 0", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2023-06-06T04:50:18Z (GMT). No. of bitstreams: 0\n Previous issue date: 2023", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "66", "language": "", "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.language.iso", "value": "eng", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": null, "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.subject.other", "value": "electrocardiography", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "myocardial fibrosis", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "masters athlete", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.title", "value": "Resting electrocardiography for analysis of potential myocardial fibrosis markers : evidence from the 2022 World Masters Athletics Championships", "language": "", "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", "value": "master thesis", "language": null, "element": "type", "qualifier": null, "schema": "dc"}, {"key": "dc.identifier.urn", "value": "URN:NBN:fi:jyu-202306063518", "language": "", "element": "identifier", "qualifier": "urn", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Master\u2019s thesis", "language": "en", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Pro gradu -tutkielma", "language": "fi", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Liikuntatieteellinen tiedekunta", "language": "fi", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Faculty of Sport and Health Sciences", "language": "en", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Liikunta- ja terveystieteet", "language": "fi", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Sport and Health Sciences", "language": "en", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "Jyv\u00e4skyl\u00e4n yliopisto", "language": "fi", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "University of Jyv\u00e4skyl\u00e4", "language": "en", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Fysioterapia", "language": "fi", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Physiotherapy", "language": "en", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "yvv.contractresearch.collaborator", "value": "business", "language": "", "element": "contractresearch", "qualifier": "collaborator", "schema": "yvv"}, {"key": "yvv.contractresearch.funding", "value": "0", "language": "", "element": "contractresearch", "qualifier": "funding", "schema": "yvv"}, {"key": "yvv.contractresearch.initiative", "value": "student", "language": "", "element": "contractresearch", "qualifier": "initiative", "schema": "yvv"}, {"key": "dc.type.coar", "value": "http://purl.org/coar/resource_type/c_bdcc", "language": null, "element": "type", "qualifier": "coar", "schema": "dc"}, {"key": "dc.rights.copyright", "value": "\u00a9 The Author(s)", "language": null, "element": "rights", "qualifier": "copyright", "schema": "dc"}, {"key": "dc.rights.accesslevel", "value": "restrictedAccess", "language": null, "element": "rights", "qualifier": "accesslevel", "schema": "dc"}, {"key": "dc.type.publication", "value": "masterThesis", "language": null, "element": "type", "qualifier": "publication", "schema": "dc"}, {"key": "dc.subject.oppiainekoodi", "value": "50422", "language": "", "element": "subject", "qualifier": "oppiainekoodi", "schema": "dc"}, {"key": "dc.subject.yso", "value": "urheilijat", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "syd\u00e4n", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "EKG", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "fibroosi", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "syd\u00e4n", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "athletes", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "heart", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "ECG", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "fibrosis", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "heart", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.rights.url", "value": "https://rightsstatements.org/page/InC/1.0/", "language": null, "element": "rights", "qualifier": "url", "schema": "dc"}, {"key": "dc.rights.accessrights", "value": "The author has not given permission to make the work publicly available electronically. Therefore the material can be read only at the archival workstation at Jyv\u00e4skyl\u00e4 University Library (https://kirjasto.jyu.fi/collections/archival-workstation).", "language": "en", "element": "rights", "qualifier": "accessrights", "schema": "dc"}, {"key": "dc.rights.accessrights", "value": "Tekij\u00e4 ei ole antanut lupaa avoimeen julkaisuun, joten aineisto on luettavissa vain Jyv\u00e4skyl\u00e4n yliopiston kirjaston arkistoty\u00f6semalta. Ks. https://kirjasto.jyu.fi/kokoelmat/arkistotyoasema..", "language": "fi", "element": "rights", "qualifier": "accessrights", "schema": "dc"}]
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