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[{"key": "dc.contributor.advisor", "value": "Valkonen, Arto", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Peltonen, Risto", "language": "", "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2023-04-26T07:18:11Z", "language": null, "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2023-04-26T07:18:11Z", "language": null, "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2023", "language": "", "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/86607", "language": null, "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Ty\u00f6n kirjallisuuskatsauksessa tutkittiin N,N\u2019-substituoitujen imidatsoli-2-tionien synteesi\u00e4 ja\nniihin liittyv\u00e4\u00e4 teoriaa. N,N\u2019-Substituoituja imidatsoli-2-tioneita voidaan syntetisoida k\u00e4ytt\u00e4m\u00e4ll\u00e4\nmonia eri l\u00e4ht\u00f6aineita ja katalyyttej\u00e4. Lopputuloksena on iso skaala tuotteita. N\u00e4m\u00e4\nimidatsolijohdannaiset ovat bioaktiivisia, aivan kuten muutkin atsolit. T\u00e4st\u00e4 syyst\u00e4 imidatsoli-2-\ntionien k\u00e4yt\u00e4nn\u00f6n sovellutukset ovat bio-, maanviljely- ja l\u00e4\u00e4kekemian parissa. My\u00f6s\nkoordinaatiokemiasta l\u00f6ytyy sovellutuksia imidatsoli-2-tioneille.\nK\u00e4yt\u00e4nn\u00f6n osuudessa syntetisoitiin N,N\u2019-substituoituja imidatsoli-2-tioneita erilaisista\nbromimetyylibentseeneist\u00e4 ja imidatsolijohdannaisista. Kyseisess\u00e4 reaktiossa hy\u00f6dynnett\u00e4vi\u00e4\nimidatsolijohdannaisia tunnetaan paljon. Kaikki tehdyt reaktiot tuottivat raakatuotetta hyv\u00e4ll\u00e4\nsaannolla, mutta monet tuotteista olivat puhdistusta kaipaavia seoksia. Osa tuotteista ei\npuhdistunut yrityksist\u00e4 huolimatta tai ne menetettiin puhdistusprosessissa. Tuotteista mitattiin 1H-\n, 13C-, 1H, 13C HMBC- ja 1H, 15N korrelaatio NMR ja ESI-MS spektrit. My\u00f6s sulamispiste\nmitattiin puhtaista tuotteista. Kymmenen kiderakennetta saatiin m\u00e4\u00e4ritetty\u00e4 syntetisoiduista\ntuotteista ja nelj\u00e4 niiden komplekseista halogeenisidosdonorien kanssa\nyksikider\u00f6ntgendiffraktiomenetelm\u00e4ll\u00e4.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.abstract", "value": "The literature review of this thesis was done by reviewing articles considering synthesis of N,N\u2019-\nsubstituted imidazole-2-thiones and theory regarding them. N,N\u2019-Substituted imidazole-2-thiones\ncan be synthesized with many different starting materials and catalysts, resulting in various\ndifferent sized molecules. As all azoles, these imidazole derivates are bioactive. This is the reason\nwhy many of the practical applications of imidazole-2-thiones are in the fields of bio-, agriculturaland pharmaceutical chemistry, although there are some other applications in coordination\nchemistry as well.\nThe experimental section of this thesis is about synthesizing N,N\u2019-substituted imidazole-2-thiones\nfrom different bromomethylbenzenes and imidazole derivatives. Many imidazole derivatives are\nknown, and they can be used as reagent in this synthesis. All the experiments made worked out to\nsome degree, giving raw product in good yields. Products were dirty or mixtures and needed\npurification. Purification made yields drop and some products could not be purified or were lost\nduring purification. Standard 1H-,\n13C-,\n1H, 13C HMBC- and 1H, 15N correlation NMR and ESIMS spectra were measured from every purified sample and some of the raw products. Also melting\npoints of the pure products were measured. Ten crystal structures from the synthetic products and\nfour of their complexes with halogen bonding donors were determined with single crystal X-ray\ndiffraction method.", "language": "en", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by Paivi Vuorio (paelvuor@jyu.fi) on 2023-04-26T07:18:11Z\nNo. of bitstreams: 0", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2023-04-26T07:18:11Z (GMT). No. of bitstreams: 0\n Previous issue date: 2023", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "126", "language": "", "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.language.iso", "value": "eng", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": null, "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.title", "value": "Synthesis of N,N\u2019-substituted imidazole-2-thiones from N-substituted imidazoles", "language": "", "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", "value": "master thesis", "language": null, "element": "type", "qualifier": null, "schema": "dc"}, {"key": "dc.identifier.urn", "value": "URN:NBN:fi:jyu-202304262714", "language": "", "element": "identifier", "qualifier": "urn", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Master\u2019s thesis", "language": "en", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Pro gradu -tutkielma", "language": "fi", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Matemaattis-luonnontieteellinen tiedekunta", "language": "fi", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Faculty of Sciences", "language": "en", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Kemian laitos", "language": "fi", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Department of Chemistry", "language": "en", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "Jyv\u00e4skyl\u00e4n yliopisto", "language": "fi", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "University of Jyv\u00e4skyl\u00e4", "language": "en", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Orgaaninen kemia", "language": "fi", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Organic Chemistry", "language": "en", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "yvv.contractresearch.funding", "value": "0", "language": "", "element": "contractresearch", "qualifier": "funding", "schema": "yvv"}, {"key": "dc.type.coar", "value": "http://purl.org/coar/resource_type/c_bdcc", "language": null, "element": "type", "qualifier": "coar", "schema": "dc"}, {"key": "dc.rights.copyright", "value": "\u00a9 The Author(s)", "language": null, "element": "rights", "qualifier": "copyright", "schema": "dc"}, {"key": "dc.rights.accesslevel", "value": "openAccess", "language": null, "element": "rights", "qualifier": "accesslevel", "schema": "dc"}, {"key": "dc.type.publication", "value": "masterThesis", "language": null, "element": "type", "qualifier": "publication", "schema": "dc"}, {"key": "dc.subject.oppiainekoodi", "value": "4035", "language": "", "element": "subject", "qualifier": "oppiainekoodi", "schema": "dc"}, {"key": "dc.subject.yso", "value": "orgaaninen kemia", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "kemia", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "atsolit", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "synteesi", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "reaktiot", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "organic chemistry", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "chemistry", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "azoles", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "synthesis", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "reactions", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.rights.url", "value": "https://rightsstatements.org/page/InC/1.0/", "language": null, "element": "rights", "qualifier": "url", "schema": "dc"}]
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