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[{"key": "dc.contributor.advisor", "value": "Parkkari, Jari", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.advisor", "value": "Sj\u00f6ros, Tanja", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.advisor", "value": "Heinonen, Ilkka", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Ylinen, Venla", "language": "", "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2022-05-09T05:28:11Z", "language": null, "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2022-05-09T05:28:11Z", "language": null, "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2022", "language": "", "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/80924", "language": null, "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "T\u00e4m\u00e4n tutkimuksen tarkoituksena oli selvitt\u00e4\u00e4, onko paikallaanolon v\u00e4hent\u00e4misell\u00e4 vaikutusta veren paastolipidiprofiiliin henkil\u00f6ill\u00e4, jotka t\u00e4ytt\u00e4v\u00e4t metabolisen oireyhtym\u00e4n kriteerit. Lis\u00e4ksi tarkasteltiin lipidien pitoisuuksien muutosten yhteytt\u00e4 liikkumisen, kehonkoostumuksen sek\u00e4 makroravintoaineiden saannin muutoksiin. Paikallaanolon on todettu lis\u00e4\u00e4v\u00e4n riski\u00e4 sairastua syd\u00e4n- ja verenkiertoelimist\u00f6 sairauksiin, tyypin kaksi diabetekseen sek\u00e4 sy\u00f6p\u00e4\u00e4n. Lis\u00e4ksi runsas paikallaanolo nostaa kuolleisuusriski\u00e4. Metabolinen oireyhtym\u00e4 on oirekasauma, johon liittyy ylipainon lis\u00e4ksi muun muassa h\u00e4iriintyneit\u00e4 lipidiarvoja eli dyslipidemiaa. Dyslipidemia on paikallaanolon tavoin yhteydess\u00e4 muun muassa syd\u00e4n- ja verisuonitauteihin sek\u00e4 kohonneeseen kuolleisuusriskiin.\n\n64 henkil\u00f6\u00e4 satunnaistettiin interventio- ja kontrolliryhmiin. Interventioryhm\u00e4\u00e4n kuuluvia (n=33) ohjeistettiin v\u00e4hent\u00e4m\u00e4\u00e4n paikallaanoloa liikuskelua lis\u00e4\u00e4m\u00e4ll\u00e4. T\u00e4m\u00e4 toteutettiin esimerkiksi tauottamalla pitk\u00e4kestoista istumista ilman merkitt\u00e4v\u00e4\u00e4 reippaan ja rasittavan liikunnan lis\u00e4\u00e4mist\u00e4. Kontrolliryhm\u00e4\u00e4 (n=31) ohjeistettiin s\u00e4ilytt\u00e4m\u00e4\u00e4n tavanomainen aktiivisuustaso. Lipidiarvot mitattiin veren plasmasta molemmilta ryhmilt\u00e4 ennen ja j\u00e4lkeen intervention. Paikallaanoloa mitattiin vy\u00f6t\u00e4r\u00f6lle asetettavalla kiihtyvyysmittarilla. \n\nPaikallaanolon v\u00e4hent\u00e4misell\u00e4 noin tunnilla p\u00e4iv\u00e4ss\u00e4 ei havaittu olevan tilastollisesti merkitsev\u00e4\u00e4 vaikutusta veren lipidiarvoihin (HDL- ja LDL-kolesteroli, kokonaiskolesteroli, HDL-kolesterolin prosentuaalinen osuus, triglyseridit sek\u00e4 vapaat rasvahapot). Ajan my\u00f6t\u00e4 heikkenemist\u00e4 tapahtui molemmissa ryhmiss\u00e4 HDL%:n osalta (p=0,047). LDL-kolesterolipitoisuuden muutos oli positiivisesti yhteydess\u00e4 liikkumisen muutoksen kanssa (r=0,35 p=0,02). T\u00e4m\u00e4n lis\u00e4ksi triglyseridien muutos korreloi positiivisesti rasvattoman massan muutoksen kanssa (r=0,31, p = 0,019). Muutokset muissa lipideiss\u00e4 eiv\u00e4t korreloineet liikkumisen tai ravintoaineiden saannin kanssa.\n\nT\u00e4m\u00e4n tutkielman tulosten perusteella noin tunti v\u00e4hemm\u00e4n paikallaanoloa ei riit\u00e4 tuomaan suotuisia muutoksia lipidiprofiiliin henkil\u00f6ill\u00e4, joilla on metabolinen oireyhtym\u00e4. Annos-vaste-suhdetta ei voida t\u00e4m\u00e4n tutkielman perusteella sanoa. Liikuntasuosituksia noudattamalla on mahdollista pienent\u00e4\u00e4 paikallaanolosta aiheutuvia riskej\u00e4.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.abstract", "value": "The purpose of this study was whether sedentary behavior (SB) (e.g., sitting) reduction for one hour per day improves blood lipid profile, including HDL- and LDL-cholesterol, total cholesterol, triglycerides (TG) and free fatty acids (FFA). It is hypothesized that reduced sitting improves concentrations of these markers without formal physical activity. To date only few long-term interventional studies have investigated the relation between device-based SB and blood lipids. \n\nSixty-four subjects with Metabolic Syndrome (MetS) were randomly assigned to intervention (n=33) and control group (n=31). The intervention group were encouraged to reduce their daily sitting without formal PA while the control group were advised to maintain their usual SB levels. Venous blood samples were drawn before and after the intervention to determine the fasting lipid profile. SB and physical activity (PA) data were collected during waking hours with hip-worn tri-axial accelerometer throughout the intervention. Body composition was measured by air displacement plethysmography before and after the trial and nutritional intake by 4-day food diaries before and at the end of the intervention. Linear mixed models were used to determine the mean change differences between groups\n\nThe HDL percentage of total plasma cholesterol decreased during the intervention (p=0.047), but there were no significant differences between groups in any of the measured blood lipids. The changes in LDL cholesterol and PA had significant positive correlation (r=0.35, p=0.02). Changes in triglycerides and changes in fat free mass were positively associated (r=0.31, p = 0.019). The changes in other plasma lipids were not significantly associated with body composition, nutrition, or PA markers. \n\n\nAiming at a one-hour reduction in SB seems not to be effective to improve blood lipid profile during six months in adults with MetS. Therefore, improving plasma lipid profile and thus diminishing the risk of cardiometabolic diseases and premature death might require interventions that aim to increase PA. To maintain a healthy plasma lipid profile, it is essential to follow the PA and SB guidelines, limit the time spent in SB, and follow a healthy diet.", "language": "en", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by Paivi Vuorio (paelvuor@jyu.fi) on 2022-05-09T05:28:11Z\nNo. of bitstreams: 0", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2022-05-09T05:28:11Z (GMT). No. of bitstreams: 0\n Previous issue date: 2022", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "68", "language": "", "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.format.mimetype", "value": "application/pdf", "language": null, "element": "format", "qualifier": "mimetype", "schema": "dc"}, {"key": "dc.language.iso", "value": "fin", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.subject.other", "value": "vapaat rasvahapot", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "paikallaanolo", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "sedentary behavior", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "free fatty acids", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.title", "value": "Paikallaanolon v\u00e4hent\u00e4misen vaikutus lipidiarvoihin henkil\u00f6ill\u00e4, joilla on metabolinen oireyhtym\u00e4", "language": "", "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", "value": "master thesis", "language": null, "element": "type", "qualifier": null, "schema": "dc"}, {"key": "dc.identifier.urn", "value": "URN:NBN:fi:jyu-202205092577", "language": "", "element": "identifier", "qualifier": "urn", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Pro gradu -tutkielma", "language": "fi", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Master\u2019s thesis", "language": "en", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Liikuntatieteellinen tiedekunta", "language": "fi", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Faculty of Sport and Health Sciences", "language": "en", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Liikunta- ja terveystieteet", "language": "fi", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Sport and Health Sciences", "language": "en", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "Jyv\u00e4skyl\u00e4n yliopisto", "language": "fi", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "University of Jyv\u00e4skyl\u00e4", "language": "en", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Liikuntal\u00e4\u00e4ketiede", "language": "fi", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Sport Medicine", "language": "en", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "yvv.contractresearch.funding", "value": "0", "language": "", "element": "contractresearch", "qualifier": "funding", "schema": "yvv"}, {"key": "dc.type.coar", "value": "http://purl.org/coar/resource_type/c_bdcc", "language": null, "element": "type", "qualifier": "coar", "schema": "dc"}, {"key": "dc.rights.accesslevel", "value": "restrictedAccess", "language": null, "element": "rights", "qualifier": "accesslevel", "schema": "dc"}, {"key": "dc.type.publication", "value": "masterThesis", "language": null, "element": "type", "qualifier": "publication", "schema": "dc"}, {"key": "dc.subject.oppiainekoodi", "value": "5042", "language": "", "element": "subject", "qualifier": "oppiainekoodi", "schema": "dc"}, {"key": "dc.subject.yso", "value": "istuminen", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "metabolinen oireyhtym\u00e4", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "dyslipidemia", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "cholesterol", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "lipids", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "LDL cholesterol", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "HDL cholesterol", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "cardiovascular diseases", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "overweight", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "triglycerides", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.format.content", "value": "fulltext", "language": null, "element": "format", "qualifier": "content", "schema": "dc"}, {"key": "dc.rights.url", "value": "https://rightsstatements.org/page/InC/1.0/", "language": null, "element": "rights", "qualifier": "url", "schema": "dc"}, {"key": "dc.rights.accessrights", "value": "The author has not given permission to make the work publicly available electronically. Therefore the material can be read only at the archival workstation at Jyv\u00e4skyl\u00e4 University Library (https://kirjasto.jyu.fi/collections/archival-workstation).", "language": "en", "element": "rights", "qualifier": "accessrights", "schema": "dc"}, {"key": "dc.rights.accessrights", "value": "Tekij\u00e4 ei ole antanut lupaa avoimeen julkaisuun, joten aineisto on luettavissa vain Jyv\u00e4skyl\u00e4n yliopiston kirjaston arkistoty\u00f6semalta. Ks. https://kirjasto.jyu.fi/kokoelmat/arkistotyoasema..", "language": "fi", "element": "rights", "qualifier": "accessrights", "schema": "dc"}, {"key": "dc.type.okm", "value": "G2", "language": null, "element": "type", "qualifier": "okm", "schema": "dc"}]
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