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[{"key": "dc.contributor.advisor", "value": "Valkonen, Arto", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.advisor", "value": "Happonen, Lauri", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Mattila, Milla", "language": "", "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2022-04-21T06:34:56Z", "language": null, "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2022-04-21T06:34:56Z", "language": null, "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2022", "language": "", "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/80661", "language": null, "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Halogeenisidos on elektronik\u00f6yh\u00e4n halogeenin positiivisen osittaisvarauksen ja elektronirikkaan akseptorin muodostama heikko vuorovaikutus, joka perustuu elektronitiheyden jakamiseen. Tutkimuskohteena halogeenisidos on varsin uusi, ja suurin osa tutkimuksesta on kohdistunut typen ominaisuuksiin. Rikki on kuitenkin lupaava halogeenisidosakseptori ja useita rikki\u00e4 sis\u00e4lt\u00e4vi\u00e4 akseptorimolekyylej\u00e4 on raportoitu viime vuosien aikana.\nRikki\u00e4 hy\u00f6dynt\u00e4viin akseptoreihin kuuluu tioneja, organosulfideja ja tiosyanaatti-anioneja. Rikin ominaisuudet tekev\u00e4t siit\u00e4 monipuoliset akseptorin: sen vapaat elektroniparit mahdollistavat sitoutumisen monen donorin kanssa ja tekev\u00e4t sidoskulmista joustavampia. Donori-akseptori-systeemeiss\u00e4 rikkiyhdisteet halogeenisitoutuvat erityisesti organohalidien ja jodimolekyylin kanssa muodostaen tyypillisesti pitki\u00e4 ketjurakenteita. Monissa yhdisteiss\u00e4 on my\u00f6s muihin heikkoihin vuorovaikutuksiin mahdollistavia kohtia.\nTutkimusprojektissa valmistettiin joukko tiourea-yksik\u00f6it\u00e4 sis\u00e4lt\u00e4vi\u00e4 yhdisteit\u00e4, jotka mahdollisesti pystyv\u00e4t toimimaan halogeenisidosakseptoreina. Valmiista yhdisteist\u00e4 kasvatettiin kiteit\u00e4 halogeenisidosdonorien kanssa, jotta niiden kiderakenteesta pystytt\u00e4isiin havaitsemaan rikin ja jodin v\u00e4lille syntyvi\u00e4 halogeenisidoksia.\nSynteesikohteet olivat bentseenipohjaisia kolmi-, neli- ja kuusihaaraisia yhdisteit\u00e4 ja resorsinareenipohjaisia kavitandeja. Kolmihaaraisten reseptorien valmistaminen onnistui hyvin, l\u00e4hes kaikki synteesit tuottivat puhdasta tuotetta hyvin saannoin. Nelihaaraisten reseptorien valmistamista vaikeutti tiosyanaatin liittyminen rakenteeseen v\u00e4\u00e4r\u00e4st\u00e4 p\u00e4\u00e4st\u00e4, jolloin jatkoreaktioon tarvittavaa muotoa syntyi vain v\u00e4h\u00e4n. Kuusihaarainen l\u00e4ht\u00f6aine ei tuottanut lainkaan tuotetta. Resorsinareenikavitandit onnistuttiin valmistamaan, mutta pitk\u00e4 synteesireitti toistuvine puhdistuksineen pienensi lopputuotteen saantoa. Suurin haaste oli kuitenkin yhdisteiden kiteytt\u00e4minen halogeenisidosdonorien kanssa akseptorien huonon liukoisuuden takia. Useasta kymmenest\u00e4 kiteytyksest\u00e4 vain yksi tuotti mittauskelpoisia kiteit\u00e4 ty\u00f6n aikarajan puitteissa. 1,1',1''-((2,4,6-Trietyylibentseeni-1,3,5-triyyli)tris(metyleeni))tris(3-butyylitiourea):n rikkiatomien havaittiin muodostaneen yhteens\u00e4 nelj\u00e4 itsen\u00e4ist\u00e4, vahvaa halogeenisidosta 1:2 1,3-dijoditetrafluoribentseenin kanssa.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by Paivi Vuorio (paelvuor@jyu.fi) on 2022-04-21T06:34:56Z\nNo. of bitstreams: 0", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2022-04-21T06:34:56Z (GMT). No. of bitstreams: 0\n Previous issue date: 2022", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "177", "language": "", "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.format.mimetype", "value": "application/pdf", "language": null, "element": "format", "qualifier": "mimetype", "schema": "dc"}, {"key": "dc.language.iso", "value": "fin", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.subject.other", "value": "halogeenisidos", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "heikot vuorovaikutukset", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.title", "value": "Rikki halogeenisidosakseptorina", "language": "", "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", "value": "master thesis", "language": null, "element": "type", "qualifier": null, "schema": "dc"}, {"key": "dc.identifier.urn", "value": "URN:NBN:fi:jyu-202204212343", "language": "", "element": "identifier", "qualifier": "urn", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Pro gradu -tutkielma", "language": "fi", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Master\u2019s thesis", "language": "en", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Matemaattis-luonnontieteellinen tiedekunta", "language": "fi", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Faculty of Sciences", "language": "en", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Kemian laitos", "language": "fi", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Department of Chemistry", "language": "en", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "Jyv\u00e4skyl\u00e4n yliopisto", "language": "fi", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "University of Jyv\u00e4skyl\u00e4", "language": "en", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Orgaaninen kemia", "language": "fi", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Organic Chemistry", "language": "en", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "yvv.contractresearch.funding", "value": "0", "language": "", "element": "contractresearch", "qualifier": "funding", "schema": "yvv"}, {"key": "dc.type.coar", "value": "http://purl.org/coar/resource_type/c_bdcc", "language": null, "element": "type", "qualifier": "coar", "schema": "dc"}, {"key": "dc.rights.accesslevel", "value": "openAccess", "language": null, "element": "rights", "qualifier": "accesslevel", "schema": "dc"}, {"key": "dc.type.publication", "value": "masterThesis", "language": null, "element": "type", "qualifier": "publication", "schema": "dc"}, {"key": "dc.subject.oppiainekoodi", "value": "4035", "language": "", "element": "subject", "qualifier": "oppiainekoodi", "schema": "dc"}, {"key": "dc.subject.yso", "value": "rikki", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "kemia", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "halogeenit", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "orgaaninen kemia", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.format.content", "value": "fulltext", "language": null, "element": "format", "qualifier": "content", "schema": "dc"}, {"key": "dc.rights.url", "value": "https://rightsstatements.org/page/InC/1.0/", "language": null, "element": "rights", "qualifier": "url", "schema": "dc"}, {"key": "dc.type.okm", "value": "G2", "language": null, "element": "type", "qualifier": "okm", "schema": "dc"}]
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