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[{"key": "dc.contributor.advisor", "value": "Laukkanen, Jari", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.advisor", "value": "Kujala, Urho", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Rajavaara, Johanna", "language": "", "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2021-06-11T12:11:22Z", "language": null, "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2021-06-11T12:11:22Z", "language": null, "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2021", "language": "", "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/76467", "language": null, "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Lihavuuden ja liikkumattomuuden lis\u00e4\u00e4ntymisen my\u00f6t\u00e4 metabolisesta oireyhtym\u00e4st\u00e4 (MBO) on muodostunut maailmanlaajuinen kansanterveydellinen ongelma. Kardiorespiratorista kuntoa kuvaavan VO2max:n on painoon suhteutettuna todettu olevan yhteydess\u00e4 MBO:\u00e4n. Eripainoisten ihmisten vertailussa olisi kuitenkin parempi k\u00e4ytt\u00e4\u00e4 rasvattomaan painoon suhteutettuja arvoja. VO2max:n lis\u00e4ksi syd\u00e4men iskutilavuutta kuvaava happipulssi on mielenkiintoinen kardiorespiratorisen kunnon muuttuja, jonka yhteytt\u00e4 MBO:\u00e4n ei ole viel\u00e4 tutkittu. T\u00e4m\u00e4n tutkimuksen tarkoituksena oli selvitt\u00e4\u00e4, ovatko VO2max ja maksimaalinen happipulssi sek\u00e4 painoon ett\u00e4 rasvattomaan painoon suhteutettuina yhteydess\u00e4 MBO:n esiintyvyyteen ja sen riskitekij\u00f6iden kasautuvuuteen henkil\u00f6ill\u00e4, joilla on syd\u00e4n- ja verisuonitautien riskitekij\u00f6it\u00e4. Tutkimusaineisto oli osa laajempaa HealthBeat-tutkimusta. Tutkittavilla oli todettu verenpainetauti ja/tai tyypin 2 diabetes tai sen esiaste. VO2max ja maksimaalinen happipulssi mitattiin suoralla menetelm\u00e4ll\u00e4 maksimaalisessa rasituskokeessa ja arvot suhteutettiin kehon painoon ja rasvattomaan painoon. Plasman rasva-arvoista ja verensokeriarvoista, diagnosoidusta tyypin 2 diabeteksesta, mitatusta verenpaineesta ja vy\u00f6t\u00e4r\u00f6nymp\u00e4ryksen pituudesta muodostettiin summamuuttuja MBO:n diagnosoimiseen. Tilastolliset analyysit toteutettiin SPSS Statistics 26 -ohjelmalla hy\u00f6dynt\u00e4en ristiintaulukointia ja sen suhteellisten riskien laskentaa ja \u03c7\u00b2-testi\u00e4, yksisuuntaista varianssianalyysi\u00e4 (ANOVA) ja riippumattomien otosten t-testi\u00e4. MBO:n esiintyvyys tutkimusjoukossa (n=65) oli korkea (80 %). Sek\u00e4 VO2max ett\u00e4 maksimaalinen happipulssi olivat yhteydess\u00e4 MBO:n esiintyvyyteen ja riskitekij\u00f6iden kasautuvuuteen. Painoon suhteutetuilta VO2max- ja happipulssiarvoiltaan parhaissa kuntoryhmiss\u00e4 MBO:n esiintyvyys ja riskitekij\u00e4m\u00e4\u00e4r\u00e4 olivat huomattavasti matalampia verrattuna keskivertoon ja heikoimpaan kuntoryhm\u00e4\u00e4n. Rasvattomaan painoon suhteutetuilta arvoiltaan parhaat kuntoryhm\u00e4t erosivat tilastollisesti merkitsev\u00e4sti vain heikoimmista kuntoryhmist\u00e4 MBO:n ja riskitekij\u00e4m\u00e4\u00e4r\u00e4n osalta. Painoon suhteutetuilta VO2max- ja happipulssiarvoiltaan heikoimmissa kuntoryhmiss\u00e4 riskit korkeammalle MBO:n riskitekij\u00e4m\u00e4\u00e4r\u00e4lle olivat 5,7- ja 8,1-kertaiset verrattuna parhaaseen kuntoryhm\u00e4\u00e4n. Rasvattomaan painoon suhteuttaessa riskit olivat 2,8- ja 2,4-kertaiset. Tulokset vahvistivat aiempaa tutkimustietoa VO2max:n yhteydest\u00e4 MBO:\u00e4n ja sen riskitekij\u00e4m\u00e4\u00e4r\u00e4\u00e4n. Happipulssin yhteytt\u00e4 MBO:\u00e4n ei ollut aiemmin tutkittu, mutta se ei tuonut merkitt\u00e4v\u00e4\u00e4 lis\u00e4arvoa kardiorespiratorisen kunnon mittarina. VO2max ja maksimaalinen happipulssi olivat n\u00e4enn\u00e4isesti hyvin samalla tavalla yhteydess\u00e4 MBO:\u00e4n ja riskitekij\u00e4m\u00e4\u00e4r\u00e4\u00e4n. Kuntoryhmiin sijoittumisessa oli kuitenkin vaihtelua yksil\u00f6tasolla riippuen siit\u00e4, kumpaa muuttuja oli mittarina ja suhteutettiinko arvot painoon vai rasvattomaan painoon. Lis\u00e4tutkimusta tarvitaan suuremmilla otoksilla seurantatutkimuksien muodossa niin, ett\u00e4 muuttujat on suhteutettu rasvattomaan painoon. Tutkimustulokset korostavat hyv\u00e4n kardiorespiratorisen kunnon merkityst\u00e4 MBO:lt\u00e4 suojaavana tekij\u00e4n\u00e4 syd\u00e4n- ja verisuonitautien riskitekij\u00f6it\u00e4 omaavilla ty\u00f6ik\u00e4isill\u00e4.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Due to increased levels of obesity and physical inactivity, metabolic syndrome (MBO) has become a worldwide public health problem. VO2max, which indicates cardiorespiratory fitness (CRF), has been found to be associated with MBO when relative to body mass. However, for comparison of VO2max across people with different body mass, it is better to use values relative to fat free mass. In addition to VO2max, oxygen pulse (surrogate to stroke volume) is an interesting parameter of CRF and its relation to MBO has not been studied yet. The aim of this study was to explore the association of VO2max and maximal oxygen pulse, both relative to body mass and fat free mass, with the prevalence of MBO and clustering of its risk factors in adults who already have some risk factors for cardiovascular diseases (CVD). The research data was part of broader HealthBeat study sample. Subjects had been diagnosed with hypertension and/or type 2 diabetes or pre-diabetes. VO2max and maximal oxygen pulse were measured directly by respiratory gas analysis during maximum exercise testing and the values were expressed relative to body mass and fat free mass. A sum variable for MBO diagnosis was created based on plasma lipid profile and blood glucose, diagnosed type 2 diabetes, blood pressure and waistline measurement. The statistical analysis of the data was carried out by SPSS Statistics 26 software, using cross tabulation and its relative risk calculation and \u03c7\u00b2-test, one-way analysis of variance (ANOVA) and independent samples t-test. The prevalence of MBO in the study sample (n=65) was high (80 %). Both VO2max and maximal oxygen pulse were associated with the prevalence of MBO and the clustering of its risk factors. The prevalence of MBO and the amount of risk factors were considerably lower in the groups with the highest values of VO2max and maximal oxygen pulse relative to body mass when compared to the average and the weakest fitness group. When the values were relative to fat free mass, there was a statistically significant difference only between the highest and the weakest fitness group regarding MBO and the amount of risk factors. Based on VO2max and oxygen pulse values relative to body mass, the weakest fitness groups had 5.7-fold and 8.1-fold risks for the higher amount of MBO risk factors compared to the best fitness group. The risks were 2.8- and 2.4-fold when the values were relative to fat free mass. The results supported previous studies regarding the association of VO2max with MBO and the clustering of risk factors. The association between maximal oxygen pulse and MBO had not been studied yet, but it did not give added value alongside VO2max. VO2max and maximal oxygen pulse were seemingly similarly associated with MBO and the amount of risk factors. However, there were variation in the fitness group placement at individual level depending on the used parameter and value proportionately. Further study is needed with larger study samples in follow-up design, where parameters are relative to fat free mass. Results highlight the importance of good CRF as a protective factor against MBO in adults with risk factors for CVD.", "language": "en", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by Miia Hakanen (mihakane@jyu.fi) on 2021-06-11T12:11:22Z\nNo. of bitstreams: 0", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2021-06-11T12:11:22Z (GMT). No. of bitstreams: 0\n Previous issue date: 2021", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "62", "language": "", "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.format.mimetype", "value": "application/pdf", "language": null, "element": "format", "qualifier": "mimetype", "schema": "dc"}, {"key": "dc.language.iso", "value": "fin", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.subject.other", "value": "kardiorespiratorinen kunto", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "VO2max", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "maksimaalinen hapenottokyky", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "happipulssi", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.title", "value": "Kardiorespiratorisen kunnon yhteys metaboliseen oireyhtym\u00e4\u00e4n verenpainetautia ja/tai tyypin 2 diabetesta sairastavilla", "language": "", "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", "value": "master thesis", "language": null, "element": "type", "qualifier": null, "schema": "dc"}, {"key": "dc.identifier.urn", "value": "URN:NBN:fi:jyu-202106113673", "language": "", "element": "identifier", "qualifier": "urn", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Pro gradu -tutkielma", "language": "fi", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Master\u2019s thesis", "language": "en", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Liikuntatieteellinen tiedekunta", "language": "fi", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Faculty of Sport and Health Sciences", "language": "en", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Liikunta- ja terveystieteet", "language": "fi", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Sport and Health Sciences", "language": "en", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "Jyv\u00e4skyl\u00e4n yliopisto", "language": "fi", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "University of Jyv\u00e4skyl\u00e4", "language": "en", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Liikuntal\u00e4\u00e4ketiede", "language": "fi", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Sport Medicine", "language": "en", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "yvv.contractresearch.funding", "value": "0", "language": "", "element": "contractresearch", "qualifier": "funding", "schema": "yvv"}, {"key": "dc.type.coar", "value": "http://purl.org/coar/resource_type/c_bdcc", "language": null, "element": "type", "qualifier": "coar", "schema": "dc"}, {"key": "dc.rights.accesslevel", "value": "openAccess", "language": null, "element": "rights", "qualifier": "accesslevel", "schema": "dc"}, {"key": "dc.type.publication", "value": "masterThesis", "language": null, "element": "type", "qualifier": "publication", "schema": "dc"}, {"key": "dc.subject.oppiainekoodi", "value": "5042", "language": "", "element": "subject", "qualifier": "oppiainekoodi", "schema": "dc"}, {"key": "dc.subject.yso", "value": "liikunta", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "riskitekij\u00e4t", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "metabolinen oireyhtym\u00e4", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.format.content", "value": "fulltext", "language": null, "element": "format", "qualifier": "content", "schema": "dc"}, {"key": "dc.rights.url", "value": "https://rightsstatements.org/page/InC/1.0/", "language": null, "element": "rights", "qualifier": "url", "schema": "dc"}, {"key": "dc.type.okm", "value": "G2", "language": null, "element": "type", "qualifier": "okm", "schema": "dc"}]
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