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[{"key": "dc.contributor.advisor", "value": "Laukkanen, Jari", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.advisor", "value": "Pekkala, Satu", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.advisor", "value": "Ahtiainen, Juha", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Salmi, Vera", "language": "", "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2021-05-28T09:47:21Z", "language": null, "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2021-05-28T09:47:21Z", "language": null, "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2021", "language": "", "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/76026", "language": null, "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Kehonkoostumuksen muutosten on todettu olevan yhteydess\u00e4 suolistomikrobiston koostumuksen muutoksiin. Urheilijoiden painonpudotuksen vaikutuksia suolistomikrobistoon ei kuitenkaan ole aiemmin tutkittu. Fitness- ja kehonrakennuslajien kilpailijat valmistautuvat kilpailuun keskim\u00e4\u00e4rin 20 viikon ajan v\u00e4hent\u00e4m\u00e4ll\u00e4 kehon rasvamassaa. T\u00e4m\u00e4n tutkimuksen tarkoituksena oli selvitt\u00e4\u00e4, muuttuuko fitness- ja kehonrakennuslajien kilpailijoiden suolistomikrobisto kilpailukauden aikana ja onko mahdollisilla suolistomikrobiston muutoksilla yhteytt\u00e4 rasvamassan sek\u00e4 rasvattoman massan muutoksiin.\nKehonkoostumus mitattiin (DXA, kaksienergisen r\u00f6ntgens\u00e4teen absorptiometria) ja ulosten\u00e4ytteet ker\u00e4ttiin kahdeksalta naisurheilijalta (ik\u00e4 28 \u00b1 4) ja kahdeltatoista miesurheilijalta (ik\u00e4 28 \u00b1 5) noin 23 viikkoa ennen kilpailua (PRE) ja viikko ennen kilpailua (POST). Energian- ja ravintoaineiden saanti analysoitiin AivoDiet-ohjelman avulla. Ulosten\u00e4ytteiden mikrobiston koostumus analysoitiin 16S rRNA geenin tunnistukseen perustuvalla sekvensoinnilla (Ion Torrent) ja CLC Microbial Genomics Package -ohjelmiston avulla. Aineiston analysointimenetelmin\u00e4 k\u00e4ytettiin Wilcoxonin merkittyjen sijaintilukujen testi\u00e4, Spearmanin j\u00e4rjestyskorrelaatiokerrointa ja Spearmanin osittaiskorrelaatiokerrointa.\nTutkimusjakson aikana tutkittavien paino ja rasvamassa v\u00e4heniv\u00e4t (p < 0,001) sek\u00e4 suolistomikrobiston beetadiversiteetti muuttui Bray-Curtis dissimilariteetti-indeksin (PERMANOVA) perusteella (p = 0,038). Ravinnon energian-, hiilihydraatin, proteiinin (p < 0,001), rasvan (p = 0,001) ja kuidun saanti (p = 0,002) laskivat. Firmikuuttien (p = 0,022), Lachnospiraceae-bakteeriheimon (p = 0,007) sek\u00e4 siihen kuuluvan tuntemattoman bakteerisuvun (p = 0,007) runsaus laski. Bakteroidien (p = 0,022), Rikenellaceae-bakteeriheimon (p = 0,007) ja Alistipes-bakteerisuvun (p = 0,007) runsaus lis\u00e4\u00e4ntyi. Burkholderiaceae-bakteeriheimon (r = 0,500, p = 0,025) sek\u00e4 Sutterella-bakteerisuvun (r = 0,515, p = 0,020) runsauden muutoksien ja rasvamassan muutoksien v\u00e4lill\u00e4 havaittiin positiivista riippuvuutta energian-, hiilihydraatin, proteiinin, rasvan, kuidun ja sakkaroosin saannista riippumatta.\nTutkimuksen tulokset osoittivat, ett\u00e4 kilpailijoiden suolistomikrobiston beetadiversiteetti ja tiettyjen mikrobien runsaus muuttuvat kilpailukaudella. Tulokset antavat viitteit\u00e4 siit\u00e4, ett\u00e4 Burkholderiaceae-heimo ja Sutterella-suku saattavat olla osallisina ruokavaliolla ja liikunnalla aikaansaatuihin kehon rasvamassan muutoksiin, vaikkakin suolistomikrobiston ja kehonkoostumuksen muutoksien v\u00e4list\u00e4 yhteytt\u00e4 selitt\u00e4v\u00e4t mekanismit vaativat lis\u00e4\u00e4 tutkimusta.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by Paivi Vuorio (paelvuor@jyu.fi) on 2021-05-28T09:47:21Z\nNo. of bitstreams: 0", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2021-05-28T09:47:21Z (GMT). No. of bitstreams: 0\n Previous issue date: 2021", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "84", "language": "", "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.format.mimetype", "value": "application/pdf", "language": null, "element": "format", "qualifier": "mimetype", "schema": "dc"}, {"key": "dc.language.iso", "value": "fin", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.title", "value": "Kehonkoostumuksen ja suolistomikrobiston muutokset fitness- ja kehonrakennuslajien kilpailijoilla kilpailukauden aikana", "language": "", "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", "value": "master thesis", "language": null, "element": "type", "qualifier": null, "schema": "dc"}, {"key": "dc.identifier.urn", "value": "URN:NBN:fi:jyu-202105283271", "language": "", "element": "identifier", "qualifier": "urn", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Pro gradu -tutkielma", "language": "fi", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Master\u2019s thesis", "language": "en", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Liikuntatieteellinen tiedekunta", "language": "fi", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Faculty of Sport and Health Sciences", "language": "en", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Liikunta- ja terveystieteet", "language": "fi", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Sport and Health Sciences", "language": "en", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "Jyv\u00e4skyl\u00e4n yliopisto", "language": "fi", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "University of Jyv\u00e4skyl\u00e4", "language": "en", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Liikuntal\u00e4\u00e4ketiede", "language": "fi", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Sport Medicine", "language": "en", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "yvv.contractresearch.funding", "value": "0", "language": "", "element": "contractresearch", "qualifier": "funding", "schema": "yvv"}, {"key": "dc.type.coar", "value": "http://purl.org/coar/resource_type/c_bdcc", "language": null, "element": "type", "qualifier": "coar", "schema": "dc"}, {"key": "dc.rights.accesslevel", "value": "restrictedAccess", "language": null, "element": "rights", "qualifier": "accesslevel", "schema": "dc"}, {"key": "dc.type.publication", "value": "masterThesis", "language": null, "element": "type", "qualifier": "publication", "schema": "dc"}, {"key": "dc.subject.oppiainekoodi", "value": "5042", "language": "", "element": "subject", "qualifier": "oppiainekoodi", "schema": "dc"}, {"key": "dc.subject.yso", "value": "kehonkoostumus", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "fitness-urheilu", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "kehonrakennus", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "urheilijat", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "suolistomikrobisto", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.format.content", "value": "fulltext", "language": null, "element": "format", "qualifier": "content", "schema": "dc"}, {"key": "dc.rights.url", "value": "https://rightsstatements.org/page/InC/1.0/", "language": null, "element": "rights", "qualifier": "url", "schema": "dc"}, {"key": "dc.rights.accessrights", "value": "The author has not given permission to make the work publicly available electronically. Therefore the material can be read only at the archival workstation at Jyv\u00e4skyl\u00e4 University Library (https://kirjasto.jyu.fi/collections/archival-workstation).", "language": "en", "element": "rights", "qualifier": "accessrights", "schema": "dc"}, {"key": "dc.rights.accessrights", "value": "Tekij\u00e4 ei ole antanut lupaa avoimeen julkaisuun, joten aineisto on luettavissa vain Jyv\u00e4skyl\u00e4n yliopiston kirjaston arkistoty\u00f6semalta. Ks. https://kirjasto.jyu.fi/kokoelmat/arkistotyoasema..", "language": "fi", "element": "rights", "qualifier": "accessrights", "schema": "dc"}, {"key": "dc.type.okm", "value": "G2", "language": null, "element": "type", "qualifier": "okm", "schema": "dc"}]
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