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[{"key": "dc.contributor.advisor", "value": "Sillanp\u00e4\u00e4, Elina", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.advisor", "value": "Karavirta, Laura", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Tolonen, Petri", "language": "", "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2021-04-01T05:42:54Z", "language": null, "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2021-04-01T05:42:54Z", "language": null, "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2021", "language": "", "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/74924", "language": null, "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Ortostaattisella hypotensiolla (OH) tarkoitetaan asennon muutoksessa, yleens\u00e4 seisomaan noustessa, tapahtuvaa poikkeavan suurta verenpaineen laskua. OH:n esiintyvyyden arvioidaan olevan 5\u201330 % riippuen p\u00e4\u00e4asiassa i\u00e4st\u00e4, sairauksista ja l\u00e4\u00e4kkeiden k\u00e4yt\u00f6st\u00e4. OH on vakava autonomisen hermoston h\u00e4iri\u00f6, jolla arvioidaan olevan yhteyk\u00acsi\u00e4 muun muassa syd\u00e4n- ja verisuonisairauksiin, kaatumisiin ja dementiaan. Poikkeuksellisen suuri verenpaineen lasku voi aiheuttaa huimausta, v\u00e4symist\u00e4, lihastonuksen katoamista, syd\u00e4men tykytyst\u00e4, n\u00e4k\u00f6h\u00e4iri\u00f6it\u00e4, kuuloh\u00e4iri\u00f6it\u00e4 tai tajunnan menetyst\u00e4. Tajunnan menetyksist\u00e4 15 % arvioidaan johtuvan OH:sta. OH:n oireet heikent\u00e4v\u00e4t ik\u00e4\u00e4ntyneiden henkil\u00f6iden toimintakyky\u00e4 ja el\u00e4m\u00e4nlaatua sek\u00e4 voivat lis\u00e4t\u00e4 kaatumisen pelkoa.\nT\u00e4m\u00e4 pro gradu -tutkielma tarkasteli OH:n esiintyvyytt\u00e4 tuoreessa suomalaisessa v\u00e4est\u00f6kohortissa ja OH:n yhteytt\u00e4 verenpainetautiin sek\u00e4 fyysiseen aktiivisuuteen ja toimintakykyyn. Tutkimusaineistona k\u00e4ytettiin Keski-Suomessa tuotettua AGNES-aineistoa. OH:n tutkimusjoukkoon kuului 873 75-, 80- ja 85-vuotiasta henkil\u00f6\u00e4. Tietojen ker\u00e4ys tapahtui puhelin- ja kotihaastattelujen sek\u00e4 postikyselyjen ja tutkimuskeskuksessa tapahtuneiden mittausten avulla. Fyysisen aktiivisuuden arvioinnissa hy\u00f6dynnettiin UKK RM42 kiihtyvyysanturilla mitattua kiihtyvyysanturidataa sek\u00e4 reipasta liikkumista, k\u00e4vely\u00e4, seisomista ja istumista koskevaa validoitua kysely\u00e4. OH:n ja fyysi\u00acsen toimintakyvyn yhteytt\u00e4 tutkittiin analysoimalla kuuden minuutin k\u00e4velytestin tuloksia sek\u00e4 raskaista taloust\u00f6ist\u00e4 selvi\u00e4misen kyselyn tuloksia. Analyysimenetelmin\u00e4 k\u00e4ytettiin riippumattomien otosten t-testi\u00e4, varianssianalyysia (ANOVA), ristiintaulukointia ja khiin neli\u00f6testi\u00e4.\nOH:ta esiintyi 9.7 %:lla koko aineistosta. OH:n esiintyvyys oli hiukan yleisemp\u00e4\u00e4 miehill\u00e4 (10.5 %) kuin naisilla (9.2 %). Sukupuolten v\u00e4linen ero ei ollut tilastollisesti merkitsev\u00e4. OH:n esiintyvyys oli samanlaista kaikissa kolmessa ik\u00e4ryhm\u00e4ss\u00e4. Verenpainetauti oli yht\u00e4 yleist\u00e4 OH:ta sairastavilla ja terveill\u00e4. OH:ta sairastavat 75-vuotiaat naiset olivat terveit\u00e4 aktiivisempia (p = 0.015). Muilla naisryhmill\u00e4 ja miehill\u00e4 vastaavaa eroa ei havaittu. Koko aineistoa tutkittaessa OH:n ja kiihtyvyysanturin avulla ker\u00e4tyn aktiivisuustiedon v\u00e4lilt\u00e4 ei l\u00f6ytynyt tilastollisesti merkitsev\u00e4\u00e4 yhteytt\u00e4. OH:n ja fyysisen toimintakyvyn yhteyden analyysiss\u00e4 75-vuotiaiden miesten kuuden minuutin k\u00e4velytestin tuloksien mukaan OH:ta sairastavien k\u00e4velytulokset olivat terveit\u00e4 heikommat (p = 0.049). Muita miesryhmi\u00e4, naisryhmi\u00e4 ja koko aineistoa tutkittaessa, OH- ja ei-OH-ryhmien v\u00e4lill\u00e4 ei ollut eroa kuuden minuutin k\u00e4velytestiss\u00e4, eik\u00e4 raskaista taloust\u00f6ist\u00e4 selvi\u00e4misess\u00e4.\nT\u00e4m\u00e4 tutkielma vahvistaa aiempia havaintoja OH:n esiintyvyydest\u00e4 ik\u00e4\u00e4ntyneess\u00e4 v\u00e4est\u00f6ss\u00e4. Nyt tutkitussa v\u00e4est\u00f6kohortissa OH:n esiintyvyys ei kuitenkaan ollut suurempaa vanhemmissa ik\u00e4ryhmiss\u00e4. OH:n ja fyysisen aktiivisuuden v\u00e4lilt\u00e4 ei l\u00f6ytynyt koko aineistoa tarkasteltaessa tilastollisesti merkitsev\u00e4\u00e4 eroa OH:ta sairastavien ja terveiden v\u00e4lilt\u00e4. T\u00e4m\u00e4 tulos vahvistaa aiempia havaintoja. OH:ta sairastavien 75-vuotiaiden miesten heikommat k\u00e4velytestitulokset vahvistavat k\u00e4sityst\u00e4 OH:n ja fyysisen toimintakyvyn v\u00e4lisest\u00e4 yhteydest\u00e4. Muiden ik\u00e4ryhmien tai naisten tuloksissa ei eroja havaittu. Tutkimustulokset olivat samansuuntaisia aiempien tutkimustulosten kanssa, vaikka OH:n ja fyysisen toimintakyvyn yhteys ei ollut t\u00e4ss\u00e4 tutkimuksessa yht\u00e4 vahva. Aiemmat OH-tutkimukset ovat tehty palvelukotiasukkaille tai laitoshoidossa asuville. N\u00e4in ollen, t\u00e4m\u00e4 laajalla v\u00e4est\u00f6otoksella suoritettu tutkimus tuo uutta tietoa erityisesti itsen\u00e4isesti kotiolosuhteissa asuvien i\u00e4kk\u00e4iden OH:n yleisyydest\u00e4 ja yhteydest\u00e4 fyysiseen aktiivisuuteen ja toimintakykyyn.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Orthostatic hypotension (OH) refers to an abnormally large drop in blood pressure that occurs with a change in posture, usually when standing up. The prevalence of OH is estimated to be 5\u201330%, depending mainly on age, disease and medication use. OH is a serious disorder of the autonomic nervous system that is assumed to associate with cardiovascular disease, falls and dementia among other age-related disorders. An exceptionally large drop in blood pressure can cause dizziness, fatigue, loss of muscle tone, palpitations, impaired vision, hearing loss, or temporary syncope. 15% of the syncope cases are is estimated to be due to OH. Symptoms of OH impair the functioning and quality of life of older people and may increase the fear of falling.\nThis master's thesis examines the prevalence of OH in a recently studied Finnish population-based cohort study AGNES. In addition, associations between OH and hypertension, physical activity and functional capacity were investigated. The study group of OH included 873 participants, who were 75, 80 or 85 years-old. Data were collected through telephone and home interviews as well as postal surveys and measurements at the research center. Physical activity was assessed using the accelerometer data measured with the UKK RM42 accelerometer as well as the results of validated surveys on vigorous physical activity, walking, standing, and sitting. The relationship between OH and functional capacity was examined by analyzing the results of a 6-minute walk test as well as the results of a questionnaire for Activities of Daily Living concerning heavier housekeeping tasks. Independent sample t-tests analysis of variance (ANOVA) and chi-square tests were used as analytical methods.\nPrevalence of OH was 9.7 % in the total group of participants. The prevalence of OH was slightly higher among men (10.5%) compared to women (9.2 %). However, the difference between the sexes was not significant. Prevalence of OH did not differ among 75-, 80- and 85-years-old participants. OH was not associated with the incidence of hypertension. Self-reported physical activity was higher among 75-years-old women with OH compared to those without OH (p = 0.015). This difference was not observed in men or the other groups of women. In addition, any associations between OH and physical activity were not observed with accelerometer-based physical activity. In the analysis of the association between OH and functional capacity, the 6-minute walk test result for 75-year-old men was better in the non-OH group than in the OH group (p = 0.049), but no statistically significant differences were observed in the other groups. Examining the entire data, there was no difference between the OH and non-OH groups in the 6-minute walk test, nor in coping with heavier housekeeping.\nThis Master\u2019s thesis confirms the findings on the prevalence of OH in the elderly population. In the present cohort, the prevalence of OH did not increase over age. Associations between OH and physical activity was not found. This result confirms previous observations. Weaker walking test result in 75-year-old men with OH confirm the perception of a link between OH and physical capacity. No differences were observed in the outcomes of other age groups or women. The study results were in line with previous study results, although the relationship between OH and physical capacity was not as strong in this study. Previous OH studies have been conducted on service home residents or those living in institutional care. This study, which was collected from a large population sample, therefore provides new insights, especially on the prevalence and association of OH in physical activity and functional capacity in elderly people living independently at home.", "language": "en", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by Miia Hakanen (mihakane@jyu.fi) on 2021-04-01T05:42:54Z\nNo. of bitstreams: 0", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2021-04-01T05:42:54Z (GMT). No. of bitstreams: 0\n Previous issue date: 2021", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "65", "language": "", "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.format.mimetype", "value": "application/pdf", "language": null, "element": "format", "qualifier": "mimetype", "schema": "dc"}, {"key": "dc.language.iso", "value": "fin", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.subject.other", "value": "ortostaattinen hypotensio", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "ik\u00e4\u00e4ntyneet ihmiset", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.title", "value": "Ortostaattinen hypotensio ja sen yhteys fyysiseen aktiivisuuteen ja toimintakykyyn ik\u00e4\u00e4ntyneill\u00e4 ihmisill\u00e4", "language": "", "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", "value": "master thesis", "language": null, "element": "type", "qualifier": null, "schema": "dc"}, {"key": "dc.identifier.urn", "value": "URN:NBN:fi:jyu-202104012254", "language": "", "element": "identifier", "qualifier": "urn", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Pro gradu -tutkielma", "language": "fi", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Master\u2019s thesis", "language": "en", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Liikuntatieteellinen tiedekunta", "language": "fi", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Faculty of Sport and Health Sciences", "language": "en", "element": "contributor", 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