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[{"key": "dc.contributor.advisor", "value": "Sipil\u00e4, Sarianna", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Korhonen, Jesperi", "language": "", "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2020-11-19T07:58:56Z", "language": null, "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2020-11-19T07:58:56Z", "language": null, "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2020", "language": "", "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/72673", "language": null, "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Lonkkamurtuma on vakava i\u00e4kk\u00e4iden ihmisten tapaturma, joka johtuu yleisemmin kaatumisesta sek\u00e4 osteoporoosista. D-vitamiinin puute on kaatumisten sek\u00e4 osteoporoosin riskitekij\u00e4. D-vitamiinin p\u00e4\u00e4asiallinen tarkoitus on s\u00e4\u00e4dell\u00e4 elimist\u00f6n kalsiumin aineenvaihduntaa, mutta sill\u00e4 on lukuisia muita terveysvaikutuksia. D-vitamiinin puute on yhdistetty moniin eri sairauksiin ja kognitiivisen toimintakyvyn heikkenemiseen. Kognitiivisen toimintakyvyn h\u00e4iri\u00f6t vaikeuttavat selviytymist\u00e4 arkiel\u00e4m\u00e4ss\u00e4. T\u00e4ss\u00e4 tutkielmassa selvitet\u00e4\u00e4n, onko seerumin D-vitamiini pitoisuus yhteydess\u00e4 lonkkamurtumasta toipuvien i\u00e4kk\u00e4iden naisten kognitiiviseen toimintakykyyn.\nTutkielman aineistona toimii Promotion of mobility after hip fracture (Promo) -tutkimushankkeen alkumittausaineisto. Promo tutkimuksessa tutkittiin vuoden kest\u00e4v\u00e4n yksil\u00f6llisesti suunnitellun, tehostetun kotikuntoutuksen vaikutusta yli 60-vuotiaiden lonkkamurtumapotilaiden liikkumis- ja toimintakykyyn. T\u00e4m\u00e4n tutkielman aineiston muodostavat tutkimukseen osallistuneet naiset (n=57), joiden seerumin D-vitamiinipitoisuus oli mitattu alkumittausten yhteydess\u00e4 laskimoverin\u00e4ytteist\u00e4 elektrokemiluminesenssi menetelm\u00e4ll\u00e4. T\u00e4ss\u00e4 tutkielmassa riitt\u00e4v\u00e4n D-vitamiinin raja-arvoksi m\u00e4\u00e4ritettiin 50 nmol/l, sill\u00e4 tutkimusten mukaan se on riitt\u00e4v\u00e4 m\u00e4\u00e4r\u00e4 luuston ja lihaksiston hyvinvoinnin turvaamiseksi. Tutkittavien kognitiivista toimintakyky\u00e4 mitattiin MMSE-testin avulla alkumittausten yhteydess\u00e4. \nTutkittavien D-vitamiinipitoisuus ei ollut yhteydess\u00e4 MMSE-pistem\u00e4\u00e4riin (p=0.814). Korkea ik\u00e4 oli odotetusti yhteydess\u00e4 MMSE-pisteisiin (p=0.004). MMSE-pistem\u00e4\u00e4rien keskiarvot eiv\u00e4t eronneet (p=0.604), kun tutkittavat jaettiin kahteen eri ryhm\u00e4\u00e4n seerumin D-vitamiinipitoisuuden perusteella (< 50 nmol/l ja \u2265 50 nmol/l).\nSeerumin D-vitamiinitasolla ei ollut t\u00e4ss\u00e4 tutkimuksessa yhteytt\u00e4 tutkittavien kognitiiviseen toimintakykyyn. Tutkimustulokset ovat t\u00e4st\u00e4 aiheesta edelleen ristiriitaisia, mink\u00e4 vuoksi jatkotutkimuksia tarvitaan, jotta voidaan selvitt\u00e4\u00e4, onko seerumin D-vitamiinipitoisuuden ja kognitiivisen toimintakyvyn v\u00e4lill\u00e4 kausaalinen suhde.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.abstract", "value": "A hip fracture is a serious injury usually caused by fall accidents and osteoporosis. Vitamin D defiency is a risk factor falls and osteoporosis. The major function of Vitamin D is to regulate the mebolism of calcium but it also has many other beneficial health benefits. Vitamin D defiency is associated with many diseases and cognitive decline. Impairments in cognitive function lead to difficulties in daily living. The aim of this study was to examine the association between serum Vitamin D-concentration and the cognitive function of elderly women recovering from a hip fracture.\nThis study was based on baseline data of research project called \u201dPromotion of mobility after hip fracture\u201d (Promo). The aim of this research project was to investigate the effect of individually targeted, enchanced home rehabilitation program on mobility of participants over the age of 60 recovering from a hip fracture. The data of this thesis is based on women (n=57) of Promo research program whose serum vitamin D-concentration was measured at baseline. Vitamin D-concentration was analyzed from venous blood samples using Electrochemiluminescence method. Value for sufficient vitamin D level in this research is 50 nmol/ l. It is considered that 50 nmol/l is the optimal value for muscoskeletal health. Cognitive function was measured by the MMSE test at baseline. \nThere were no associations between serum Vitamin D-concentration and MMSE test scores (p=0.814). As expected, older age was associated with lower scores on MMSE test (p=0.004). There was no statistically significant difference (p=0.604) in distribution of MMSE test scores when the participants were divided in two groups based on serum vitamin D-concentration (<50 nmol/l ja \u2265 50 nmol/l).\nIn this study no association was found between serum Vitamin D-concentration and cognitive function. The findings in this research area are still contradictory which means that further exploration of causal relationship between Vitamin D-concentration and cognitive function in needed.", "language": "en", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by Paivi Vuorio (paelvuor@jyu.fi) on 2020-11-19T07:58:56Z\nNo. of bitstreams: 0", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2020-11-19T07:58:56Z (GMT). No. of bitstreams: 0\n Previous issue date: 2020", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "55", "language": "", "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.format.mimetype", "value": "application/pdf", "language": null, "element": "format", "qualifier": "mimetype", "schema": "dc"}, {"key": "dc.language.iso", "value": "fin", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.subject.other", "value": "kognitiivinen toimintakyky", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "lonkkamurtuma", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.title", "value": "Seerumin D-vitamiinipitoisuuden yhteys lonkkamurtumasta toipuvien i\u00e4kk\u00e4iden naisten kognitiiviseen toimintakykyyn", "language": "", "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", "value": "master thesis", "language": null, "element": "type", "qualifier": null, "schema": "dc"}, {"key": "dc.identifier.urn", "value": "URN:NBN:fi:jyu-202011196688", "language": "", "element": "identifier", "qualifier": "urn", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Pro gradu -tutkielma", "language": "fi", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Master\u2019s thesis", "language": "en", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Liikuntatieteellinen tiedekunta", "language": "fi", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Faculty of Sport and Health Sciences", "language": "en", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Liikunta- ja terveystieteet", "language": "fi", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Sport and Health Sciences", "language": "en", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "Jyv\u00e4skyl\u00e4n yliopisto", "language": "fi", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "University of Jyv\u00e4skyl\u00e4", "language": "en", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Gerontologia ja kansanterveys", "language": "fi", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Gerontology and Public Health", "language": "en", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "yvv.contractresearch.funding", "value": "0", "language": "", "element": "contractresearch", "qualifier": "funding", "schema": "yvv"}, {"key": "dc.type.coar", "value": "http://purl.org/coar/resource_type/c_bdcc", "language": null, "element": "type", "qualifier": "coar", "schema": "dc"}, {"key": "dc.rights.accesslevel", "value": "openAccess", "language": null, "element": "rights", "qualifier": "accesslevel", "schema": "dc"}, {"key": "dc.type.publication", "value": "masterThesis", "language": null, "element": "type", "qualifier": "publication", "schema": "dc"}, {"key": "dc.subject.oppiainekoodi", "value": "50423", "language": "", "element": "subject", "qualifier": "oppiainekoodi", "schema": "dc"}, {"key": "dc.subject.yso", "value": "D-vitamiini", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "ik\u00e4\u00e4ntyneet", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "vanhukset", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "kognitio", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.format.content", "value": "fulltext", "language": null, "element": "format", "qualifier": "content", "schema": "dc"}, {"key": "dc.rights.url", "value": "https://rightsstatements.org/page/InC/1.0/", "language": null, "element": "rights", "qualifier": "url", "schema": "dc"}, {"key": "dc.type.okm", "value": "G2", "language": null, "element": "type", "qualifier": "okm", "schema": "dc"}]
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