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[{"key": "dc.contributor.advisor", "value": "Sipil\u00e4, Sarianna", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Vidgren, Arto", "language": "", "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2020-08-28T10:09:59Z", "language": null, "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2020-08-28T10:09:59Z", "language": null, "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2020", "language": "", "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/71542", "language": null, "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Ik\u00e4\u00e4ntymiseen liittyy v\u00e4hentynyt fyysinen aktiivisuus ja lis\u00e4\u00e4ntynyt monil\u00e4\u00e4kitys. Yhdess\u00e4 n\u00e4m\u00e4 lis\u00e4\u00e4v\u00e4t huomattavasti\nfyysisen toimintakyvyn heikentymisen riski\u00e4. Monil\u00e4\u00e4kitykseksi katsotaan tilanne, jolloin henkil\u00f6ll\u00e4 on l\u00e4\u00e4k\u00e4rin\nm\u00e4\u00e4r\u00e4\u00e4m\u00e4n\u00e4 s\u00e4\u00e4nn\u00f6llisess\u00e4 k\u00e4yt\u00f6ss\u00e4 v\u00e4hint\u00e4\u00e4n viisi eri l\u00e4\u00e4kett\u00e4. T\u00e4m\u00e4n pro gradu tutkielman tarkoituksena oli\nselvitt\u00e4\u00e4, onko monil\u00e4\u00e4kityksell\u00e4 yhteys ik\u00e4\u00e4ntyneiden henkil\u00f6iden fyysiseen aktiivisuuteen ja k\u00e4velykykyyn sek\u00e4\nennustaako monil\u00e4\u00e4kitys fyysisen aktiivisuuden ja k\u00e4velykyvyn muutosta kuuden kuukauden liikuntaharjoittelun\nsek\u00e4 yhdistetyn liikunta- ja kognitiivisen harjoittelun aikana.\nTutkielman aineistona k\u00e4ytettiin Jyv\u00e4skyl\u00e4n yliopiston liikuntatieteellisen tiedekunnan ja Gerontologian\ntutkimuskeskuksen Promoting safe walking among older people (PASSWORD) -tutkimuksen alku- ja v\u00e4limittausten (6\nkk) aineistoja. Tutkittavat (n=314) olivat 70-85-vuotiaita kotona asuvia jyv\u00e4skyl\u00e4l\u00e4isi\u00e4, joilla ei ollut vakavia sairauksia\ntai kognition heikentym\u00e4\u00e4. Reseptil\u00e4\u00e4kkeiden k\u00e4ytt\u00f6\u00e4 selvitettiin kyselylomakkeen avulla ja Efficapotilastietoj\u00e4rjestelm\u00e4st\u00e4 saatujen tietojen avulla. Tutkittavat satunnaistettiin kahteen tutkimusryhm\u00e4\u00e4n;\nliikuntainterventio (LIIKU) tai liikunta- ja kognitiivinen (LIIKUKO) interventio. Liikuntainterventio sis\u00e4lsi viikoittain\nyhden ohjatun kuntosaliharjoituksen ja yhden ohjatun k\u00e4velyharjoituksen. N\u00e4iden lis\u00e4ksi tutkittaville annettiin\nkotiharjoitusohjelma, joka keskittyi alaraajojen lihasvoiman, tasapainon sek\u00e4 liikkuvuuden kehitt\u00e4miseen. Kognitiivinen\ninterventio sis\u00e4lsi toiminnanohjauksen kolmen osa-alueen, inhibition, ty\u00f6muistin ja kognitiivisen joustavuuden\nharjoittamisen. Tietokonepohjainen harjoittelu koostui nelj\u00e4st\u00e4 teht\u00e4v\u00e4st\u00e4 ja intervention edetess\u00e4 onnistumisten my\u00f6t\u00e4\ntestin suorittaminen nopeutui. T\u00e4ss\u00e4 tutkielmassa n\u00e4iden tutkimusryhmien tutkittavat jaettiin edelleen alaryhmiin\nmonil\u00e4\u00e4kityksen perusteella; monil\u00e4\u00e4kitty tai ei-monil\u00e4\u00e4kitty. Ryhmien v\u00e4lisi\u00e4 eroja fyysisen aktiivisuuden ja\nk\u00e4velykyvyn suhteen tarkasteltiin riippumattomien otosten t-testill\u00e4, \u03c72-testill\u00e4 ja Fisherin tarkalla testill\u00e4. Ryhmien\nv\u00e4lisi\u00e4 eroja liikunta-aktiivisuuden muutoksessa tarkasteltiin toistettujen mittausten varianssianalyysill\u00e4 ja siihen\nliittyv\u00e4ll\u00e4 parivertailu (post hoc) testill\u00e4.\nL\u00e4ht\u00f6tilanteessa monil\u00e4\u00e4kittyjen ja ei-monil\u00e4\u00e4kittyjen tutkittavien v\u00e4lill\u00e4 oli tilastollisesti merkitsevi\u00e4 eroja 6-minuutin\nk\u00e4velymatkan (p=0.022) ja kohtalaisen- tai reippaan aktiviteetin v\u00e4lill\u00e4 (p=0.005). Ei-monil\u00e4\u00e4kittyjen 6-minuutin\nk\u00e4velymatkan tulos oli 21.4 metri\u00e4 pidempi kuin monil\u00e4\u00e4kittyjen ja kohtalaisen- tai reippaan aktiviteetin m\u00e4\u00e4r\u00e4 p\u00e4iv\u00e4ss\u00e4\n6.8 minuuttia enemm\u00e4n kuin monil\u00e4\u00e4kityill\u00e4. Kohtalainen ja reipas aktiviteetti lis\u00e4\u00e4ntyi kaikissa tutkituissa ryhmiss\u00e4\ntilastollisesti merkitsev\u00e4sti (p<0.001) kuuden kuukauden intervention aikana. Ajan ja ryhm\u00e4n yhdysvaikutus ei ollut\ntilastollisesti merkitsev\u00e4 (p=0.966). L\u00e4\u00e4kitysryhm\u00e4t erosivat tilastollisesti merkitsev\u00e4sti (p=0.011) toisistaan\nkohtalaisen ja reippaan fyysisen aktiivisuuden suhteen yli aikapisteiden: ei-monil\u00e4\u00e4kityill\u00e4 LIIKUKO ryhm\u00e4l\u00e4isill\u00e4\np\u00e4ivitt\u00e4inen kohtalainen ja reipas fyysinen aktiivisuus oli suurempaa kuin monil\u00e4\u00e4kityill\u00e4 LIIKUKO ryhm\u00e4l\u00e4isill\u00e4.\nJohtop\u00e4\u00e4t\u00f6ksen\u00e4 todetaan, ett\u00e4 monil\u00e4\u00e4kityksell\u00e4 on yhteys ik\u00e4\u00e4ntyneiden henkil\u00f6iden fyysiseen aktiivisuuteen ja\nk\u00e4velykykyyn, mutta se ei vaikuta liikuntaintervention aiheuttamaan fyysisen aktiivisuuden muutokseen. Lis\u00e4\u00e4\ntutkimusta tarvitaan selvitt\u00e4m\u00e4\u00e4n, mitk\u00e4 l\u00e4\u00e4keaineet erityisesti yhdess\u00e4 k\u00e4ytettyn\u00e4 aiheuttavat muutoksia fyysisess\u00e4\naktiivisuudessa. Lis\u00e4ksi kognitiivisen harjoittelun mahdollisia positiivisia vaikutuksia monil\u00e4\u00e4kittyjen henkil\u00f6iden\ntoimintakykyyn tulisi tutkia tarkemmin.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Aging is associated with decreased physical activity and increased amount of polypharmacy. Together, these\nsignificantly increase the risk of physical impairment. Polypharmacy is a situation in which a person has at least five\ndifferent medications for regular use prescribed by a doctor. The purpose of this master\u2019s thesis was to find out whether\npolypharmacy has association with physical activity and walking ability among 70\u221285-years old community-dwelling\npeople and whether plolypharmacy predicts changes in physical activity and walking ability during six months of\nexercise and combined exercise and cognitive training.\nThe data of the thesis was based on the data of the baseline and 6- months follow- up measurements of the Promoting\nsafe walking among older people (PASSWORD) study of the Faculty of Sports Science of the University of Jyv\u00e4skyl\u00e4\nand the Gerontology Research Center. The subjects (n = 314) were 70-85-years old community-dwelling citizens of\nJyv\u00e4skyl\u00e4 who did not have serious illnesses or cognitive impairment. The use of prescription drugs was analyzed by\nusing a questionnaire and comparing the data from the Effica patient information system. Subjects were randomized\ninto two study groups; exercise intervention (LIIKU) or exercise and cognitive (LIIKUKO) intervention. The exercise\nintervention included one guided gym workout and one guided walking workout each week. In addition to these,\nsubjects were given a home exercise program that focused on improving lower limb muscle strength, balance, and\nmobility. Cognitive intervention included the exercise of three components of executive functions, namely inhibition,\nworking memory, and cognitive flexibility. The computer-based training consisted of four tasks, and as the intervention\nprogressed, the completion of the test accelerated with success. In this study, subjects in these study groups were further\nsubdivided into subgroups based on drug therapy; polypharmacy or non-polypharmacy. Differences between groups in\nterms of physical activity and walking ability were examined by independent sample t-test, \u03c72-test, and Fisher's exact\ntest. Differences between groups in the change in exercise activity were examined by analysis of variance of repeated\nmeasures and the associated pairwise comparision (post hoc) test.\nAt baseline, there were statistically significant differences between 6-minute walk (p = 0.022) and moderate or vigorous\nactivity (p = 0.005) between polypharmacy and non-polypharmacy groups. Subjects in the non-polypharmacy group\nwalked for 21.4 meters more in the 6-minute walking test and engaged in moderate to vigorous activity for 6.8\nminutes more per day than subjects with polypharmacy.Moderate and vigorous activity improved statistically\nsignificantly (p <0.001) in all groups studied over the six-month intervention. The interaction between time and group\nwas not statistically significant (p = 0.966). The medication groups differed statistically significantly (p=0.011) in terms\nof moderate and vigorous physical activity over time points: non-polypharmacy group with cognitive training had\nhigher daily moderate and vigorous physical activity than polypharmacy group without cognitive training.\nIn conclusion, polypharmacy is associated with physical activity and walking in older people, but does not affect the\nchange in physical activity caused by exercise intervention. More research is needed to find out which drugs, especially\nwhen used together, cause changes in physical activity. In addition, the potential positive effects of cognitive training on\nthe functional capacity of multidrug-treated individuals should be further investigated.", "language": "en", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by Paivi Vuorio (paelvuor@jyu.fi) on 2020-08-28T10:09:59Z\nNo. of bitstreams: 0", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2020-08-28T10:09:59Z (GMT). No. of bitstreams: 0\n Previous issue date: 2020", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "56", "language": "", "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.format.mimetype", "value": "application/pdf", "language": null, "element": "format", "qualifier": "mimetype", "schema": "dc"}, {"key": "dc.language.iso", "value": "fin", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.subject.other", "value": "kognitiivinen harjoittelu", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.title", "value": "Monil\u00e4\u00e4kityksen yhteys kotona asuvien 70-85 -vuotiaiden henkil\u00f6iden fyysiseen aktiivisuuteen", "language": "", "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", "value": "master thesis", "language": null, "element": "type", "qualifier": null, "schema": "dc"}, {"key": "dc.identifier.urn", "value": "URN:NBN:fi:jyu-202008285672", "language": "", "element": "identifier", "qualifier": "urn", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Pro gradu -tutkielma", "language": "fi", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Master\u2019s thesis", "language": "en", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Liikuntatieteellinen tiedekunta", "language": "fi", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Faculty of Sport and Health Sciences", "language": "en", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Liikunta- ja terveystieteet", "language": "fi", "element": "contributor", 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