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[{"key": "dc.contributor.advisor", "value": "Laukkanen, Jari", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Haapakangas, Suvi", "language": "", "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2020-06-08T09:41:27Z", "language": null, "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2020-06-08T09:41:27Z", "language": null, "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2020", "language": "", "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/69764", "language": null, "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Korkea verenpaine ja tyypin 2 diabetes ovat riskitekij\u00f6it\u00e4 lukuisille sairauksille sek\u00e4 kuolleisuudelle ja ovat yhteydess\u00e4 autonomisen hermoston toiminnan h\u00e4iri\u00f6ihin. Liikunnanaikainen liiallinen verenpaineen kohoaminen, hidas palautuminen liikunnan j\u00e4lkeen ja sykkeen ep\u00e4tavallinen k\u00e4ytt\u00e4ytyminen ovat merkkej\u00e4 autonomisen hermoston toiminnan h\u00e4iri\u00f6ist\u00e4. Sykev\u00e4livaihtelua (HRV) k\u00e4ytet\u00e4\u00e4n yleisesti kuvaamaan autonomisen hermoston tilaa. T\u00e4m\u00e4n tutkimuksen tarkoitus oli tutkia yhteyksi\u00e4 autonomisen hermoston toiminnan ja liikunnanaikaisen liiallisen verenpaineen nousun sek\u00e4 sykek\u00e4ytt\u00e4ytymisen v\u00e4lill\u00e4.\n\nT\u00e4m\u00e4 tutkimus tehtiin osana Healthbeat-tutkimusta (\u201dKunto, uni ja stressi diabetes- ja verenpainetautipotilailla\u201d), joka toteutettiin vuosina 2019-2020. Tutkimuspopulaatio koostui 18-64-vuotiaista, joilla oli todettu diabeteksen esiaste ja/tai diagnosoitu tyypin 2 diabetes viimeisen 5 vuoden sis\u00e4ll\u00e4 ja/tai verenpainetauti. T\u00e4m\u00e4n tutkimuksen otanta oli 28 henkil\u00f6\u00e4 keski-i\u00e4lt\u00e4\u00e4n 54,4 vuotta. Korkea verenpaine oli diagnosoitu 23 (82,1 %), tyypin 2 diabetes 4 (14,3%) ja esidiabetes 10 henkil\u00f6ll\u00e4 (35,7%) osallistujista. Tutkimuksen data analysoitiin IBM SPSS Statistics (26.0) \u2013 ohjelmistolla. Analysointimenetelmin\u00e4 k\u00e4ytettiin t-testi\u00e4, ristiintaulukointia, Khiin neli\u00f6 \u2013 testi\u00e4 ja Mann Whitneyn U-testi\u00e4. Autonomisen hermoston toimintaa analysoitiin nousujohteisen maksimaalisen rasitustestin yhteydess\u00e4 ryhmien v\u00e4lill\u00e4, jotka oli jaettu liikunnan aikaisen maksimaalisen systolisen verenpaineen (SBP) ja ik\u00e4vakioidun maksimaalisen sykkeen mukaan. Lis\u00e4ksi 72-tunnin HRV mittausta vertailtiin samoissa ryhmiss\u00e4.\n\nParasympaattisen hermoston aktivaatio liikunnan j\u00e4lkeen (5 min palautusjakson HF-arvo) oli ei-merkitsev\u00e4sti nopeampaa ryhm\u00e4ss\u00e4, jossa liikunnan aikainen systolinen verenpaine oli matalampi (p=0,125). Korkeamman verenpaineen ryhm\u00e4ss\u00e4 esiintyi enemm\u00e4n diabeteksen esiasteita (p=0,036), liikunnan j\u00e4lkeinen verenpaine oli korkeampi (1 min p=0,001, 3 min p=0,041) ja syke palautui liikunnasta ei-merkitsev\u00e4sti hitaammin (1 min p=0,130, 3 min p=0,113). Korkeampi ik\u00e4vakioitu syke liikunnan aikana oli yhteydess\u00e4 alhaisempaan painoon (p=0,007), pienemp\u00e4\u00e4n kehon painoindeksiin (BMI) (p=0,007), korkeampaan HDL-kolesterolipitoisuuteen (p=0,039) ja suurempaan sykereserviin (p=0,044).\n\nYhteenvetona alhaisemmat liikunnan aikaiset systolisen verenpaineen arvot voivat merkit\u00e4 korkeampaa parasympaattisen hermoston toimintaa, kun indikaattoreina k\u00e4ytet\u00e4\u00e4n HRV:t\u00e4, liikunnan j\u00e4lkeisi\u00e4 SBP-arvoja ja sykevasteita. Korkeampi liikunnan aikainen ik\u00e4vakioitu syke oli yhteydess\u00e4 positiivisiin terveysmarkkereihin.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Hypertension and type 2 diabetes are risk factors for morbidities and mortality and are associated with the autonomic nervous system (ANS) dysfunction. Dysfunction of the ANS represents itself as an exaggerated blood pressure response during and after exercise. Abnormal heart rate responses during and after exercise are a sign of imbalanced ANS as well. Heart rate variability (HRV) is commonly used to evaluate the state of the ANS. The aim of this study was to evaluate the associations of autonomic nervous system with blood pressure and heart rate responses during exercise.\n\nThis thesis was a part of the Healthbeat study (\u201cKunto, uni ja stressi diabetes- ja verenpainetautipotilailla\u201d) conducted in 2019-2020. Study population consisted of 18- to 64-year-old individuals with prediabetes and/or type 2 diabetes diagnosed during last five years and/or diagnosed hypertension. This study included 28 participants with a mean age of 54.4. High blood pressure was diagnosed with 23 (82.1%) of the participants, type 2 diabetes with 4 (14.3%) and prediabetes with 10 (35.7%) of the participants. The data were analyzed with the IBM SPSS Statistics (26.0) \u2013 software. T-test, crosstabs, Chi square (\u03c72) \u2013 test and Mann-Whitney-test were used as the analyzing methods. The participants were divided to groups according to the highest exercise-induced systolic blood pressure (SBP) response as well as the highest age-adjusted heart rate (HR) response during the maximal graded exercise test. The ANS function during the graded maximal exercise test was analyzed between groups. 72-hour recording of HRV values were compared within the groups.\n\nActivation of the parasympathetic nervous system after exercise (5 min post exercise HF value) was non-significantly higher in the group with lower SBP values during exercise (p=0.125). Higher SBP group had a higher prevalence of prediabetes (p=0.036), higher post-exercise SBP (1 min p=0.001, 3 min p=0.041) and non-significantly slower heart rate recovery (1 min p=0.130, 3 min p=0.113) than lower SBP group. Higher age-adjusted HR was associated with lower body weight (p=0.007), lower body mass index (BMI) (p=0.007), higher serum HDL-cholesterol value (p=0.039) and higher HR reserve (p=0.044).\n\nIn summary, lower SBP values during maximal exercise may indicate higher parasympathetic domination when measured with HRV, post-exercise SBP and HR responses. Higher age-adjusted HR was associated with positive health indicators.", "language": "en", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by Paivi Vuorio (paelvuor@jyu.fi) on 2020-06-08T09:41:27Z\nNo. of bitstreams: 0", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2020-06-08T09:41:27Z (GMT). No. of bitstreams: 0\n Previous issue date: 2020", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "75", "language": "", "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.format.mimetype", "value": "application/pdf", "language": null, "element": "format", "qualifier": "mimetype", "schema": "dc"}, {"key": "dc.language.iso", "value": "eng", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.subject.other", "value": "syd\u00e4men syke", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "sykev\u00e4livaihtelu", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.title", "value": "Associations of autonomic nervous system with blood pressure and heart rate responses during exercise", "language": "", "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", "value": "master thesis", "language": null, "element": "type", "qualifier": null, "schema": "dc"}, {"key": "dc.identifier.urn", "value": "URN:NBN:fi:jyu-202006084021", "language": "", "element": "identifier", "qualifier": "urn", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Pro gradu -tutkielma", "language": "fi", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Master\u2019s thesis", "language": "en", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Liikuntatieteellinen tiedekunta", "language": "fi", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Faculty of Sport and Health Sciences", "language": "en", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, 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