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[{"key": "dc.contributor.advisor", "value": "Karvanen, Juha", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Pasanen, Tiia-Maria", "language": "", "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2020-03-16T07:03:56Z", "language": null, "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2020-03-16T07:03:56Z", "language": null, "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2020", "language": "", "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/68159", "language": null, "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Tyypin 2 diabetes on Suomessa kansantaudiksi luokiteltava glukoosiaineenvaihdunnan h\u00e4iri\u00f6, joka aiheuttaa yhteiskunnalle jatkuvasti kasvavia kustannuksia ja heikent\u00e4\u00e4 sairastuneen el\u00e4m\u00e4nlaatua. Tauti todetaan tyypillisesti vasta vuosien sairastamisen j\u00e4lkeen, jolloin erilaisia oheissairauksia on jo ehtinyt synty\u00e4. Tyypin 2 diabetes esiintyy usein metabolisesta oireyhtym\u00e4st\u00e4 k\u00e4rsivill\u00e4, ja sairastumiseen on mahdollista toisinaan vaikuttaa omilla el\u00e4m\u00e4ntavoilla. Esivaiheen diabetekseen eli prediabetekseen ja piilev\u00e4n\u00e4 sairastettavaan tyypin 2 diabetekseen sairastumisen riskin arvioimista asianmukaisten taustatekij\u00f6iden perusteella voitaisiin hy\u00f6dynt\u00e4\u00e4 sek\u00e4 yksil\u00f6n ett\u00e4 yhteiskunnan hyv\u00e4ksi.\n\nT\u00e4ss\u00e4 tutkielmassa sovitetaan suomalaisia, vuosina 1884-1949 syntyneit\u00e4 entisi\u00e4 huippu-urheilijamiehi\u00e4 ja heid\u00e4n verrokkejaan kuvaavaan aineistoon tyypin 2 diabeteksen etenemist\u00e4 kuvaava tilasiirtym\u00e4malli. T\u00e4m\u00e4n mallin avulla estimoidaan siirtym\u00e4todenn\u00e4k\u00f6isyyksi\u00e4 sek\u00e4 tiettyjen taustamuuttujien vaikutusta niihin. Tilasiirtym\u00e4mallin ajatuksena nimens\u00e4 mukaisesti on, ett\u00e4 on vaihtoehtoisia tiloja, joiden v\u00e4lill\u00e4 voidaan siirty\u00e4 tietyn ajan kuluessa. Analysoitavan aineiston tulee sis\u00e4lt\u00e4\u00e4 tieto tilasta, jossa ollaan kullakin hetkell\u00e4. T\u00e4m\u00e4n tutkielman malli on hierarkkinen, ja se sovitetaan k\u00e4ytt\u00e4en R- ja JAGS-ohjelmistoja. Tilasiirtym\u00e4todenn\u00e4k\u00f6isyyksi\u00e4 ja taustamuuttujien vaikutusta estimoidaan multinomiaalisella logistisella regressiolla.\n\nSovitettava malli on yksinkertaistus laajemmasta tilasiirtym\u00e4mallista, joka ottaa huomioon piilev\u00e4n tyypin 2 diabeteksen tai prediabeteksen. Vaikka laajemman mallin teoriaa esitell\u00e4\u00e4n, sovitetaan aineistoon yksinkertaisempi malli, jonka avulla siirtym\u00e4todenn\u00e4k\u00f6isyyksien ja kovariaattien vaikutuksen estimointi n\u00e4ytt\u00e4\u00e4 onnistuvan hyvin. Tilasiirtym\u00e4todenn\u00e4k\u00f6isyyksien lis\u00e4ksi aineistosta estimoidaan prediabeteksen tai piilev\u00e4n tyypin 2 diabeteksen sairastamisen todenn\u00e4k\u00f6isyytt\u00e4 vuonna 2008.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by Miia Hakanen (mihakane@jyu.fi) on 2020-03-16T07:03:56Z\nNo. of bitstreams: 0", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2020-03-16T07:03:56Z (GMT). No. of bitstreams: 0\n Previous issue date: 2020", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "50", "language": "", "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.format.mimetype", "value": "application/pdf", "language": null, "element": "format", "qualifier": "mimetype", "schema": "dc"}, {"key": "dc.language.iso", "value": "fin", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.subject.other", "value": "Bayes-tilastotiede", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "multinomiaalinen logistinen regressio", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "prediabetes", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "tilasiirtym\u00e4", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.title", "value": "Bayes-malli tyypin 2 diabetekseen liittyville tilasiirtymille", "language": "", "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", "value": "master thesis", "language": null, "element": "type", "qualifier": null, "schema": "dc"}, {"key": "dc.identifier.urn", "value": "URN:NBN:fi:jyu-202003162406", "language": "", "element": "identifier", "qualifier": "urn", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Pro gradu -tutkielma", "language": "fi", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Master\u2019s thesis", "language": "en", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Matemaattis-luonnontieteellinen tiedekunta", "language": "fi", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Faculty of Sciences", "language": "en", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Matematiikan ja tilastotieteen laitos", "language": "fi", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Department of Mathematics and Statistics", "language": "en", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "Jyv\u00e4skyl\u00e4n yliopisto", "language": "fi", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "University of Jyv\u00e4skyl\u00e4", "language": "en", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Tilastotiede", "language": "fi", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Statistics", "language": "en", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "yvv.contractresearch.funding", "value": "0", "language": "", "element": "contractresearch", "qualifier": "funding", "schema": "yvv"}, {"key": "dc.type.coar", "value": "http://purl.org/coar/resource_type/c_bdcc", "language": null, "element": "type", "qualifier": "coar", "schema": "dc"}, {"key": "dc.rights.accesslevel", "value": "openAccess", "language": null, "element": "rights", "qualifier": "accesslevel", "schema": "dc"}, {"key": "dc.type.publication", "value": "masterThesis", "language": null, "element": "type", "qualifier": "publication", "schema": "dc"}, {"key": "dc.subject.oppiainekoodi", "value": "4043", "language": "", "element": "subject", "qualifier": "oppiainekoodi", "schema": "dc"}, {"key": "dc.subject.yso", "value": "huippu-urheilijat", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "diabetes", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "aikuistyypin diabetes", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "sairastuminen", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "tilastotiede", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "terveys", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "liikunta", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.format.content", "value": "fulltext", "language": null, "element": "format", "qualifier": "content", "schema": "dc"}, {"key": "dc.rights.url", 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