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[{"key": "dc.contributor.advisor", "value": "Parviainen, Tiina", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Siukkola, Anja", "language": "", "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Kirstin\u00e4, Linnea", "language": "", "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2020-01-08T11:42:05Z", "language": null, "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2020-01-08T11:42:05Z", "language": null, "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2019", "language": "", "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/67161", "language": null, "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Masennus on yksi suurimmista kansanterveyden ongelmista ja sill\u00e4 onkin merkitt\u00e4v\u00e4t inhimilliset ja taloudelliset vaikutukset. Masennus voi aiheuttaa monia psyykkisi\u00e4 ja kehollisia oireita. Interoseptio tarkoittaa kyky\u00e4 tunnistaa autonomisen hermoston signaaleja, kuten syd\u00e4men sykett\u00e4. T\u00e4m\u00e4 kehoaisti saattaa osallistua siihen, miten kehon tuntemukset pystyv\u00e4t vaikuttamaan mielen prosesseihin, esimerkiksi tunnekokemuksiin. Interoseptiivisella herkkyydell\u00e4 ja sen muutoksilla n\u00e4ytt\u00e4isikin olevan yhteys moniin psykiatrisiin h\u00e4iri\u00f6ihin, my\u00f6s masennukseen. Interoseptiiviset signaalit saavat aikaan mitattavia her\u00e4tevasteita aivoissa. N\u00e4it\u00e4 on tutkittu masentuneilla eritt\u00e4in v\u00e4h\u00e4n. Tutkimuksessamme tarkastelimme syd\u00e4men sykkeen havainnointiteht\u00e4v\u00e4n avulla eroavatko masentuneet ja terveet verrokkihenkil\u00f6t interoseptiivisess\u00e4 herkkyydess\u00e4. Osallistujat suorittivat syd\u00e4men syke- ja kuulohavainnon erotteluteht\u00e4v\u00e4n, jossa henkil\u00f6n tuli tarkastella, oliko \u00e4\u00e4ni\u00e4rsyke synkroniassa syd\u00e4men sykkeen kanssa. Lis\u00e4ksi tarkastelimme magnetoenkefalografialla (MEG), onko masentuneilla ja verrokeilla eroa interoseptio-teht\u00e4v\u00e4n aikaisissa aivojen her\u00e4tevasteissa temporaali- ja parietaalialueella sek\u00e4 p\u00e4\u00e4laen alueella. Ulkoisen \u00e4\u00e4ni\u00e4rsykkeen havainnointi toimi kontrollimittauksena. Masentuneiden ja verrokkien v\u00e4lill\u00e4 ei havaittu eroja interoseptiivisess\u00e4 herkkyydess\u00e4 eik\u00e4 interoseptio-teht\u00e4v\u00e4n aikaissa aivojen her\u00e4tevasteissa. Masentuneilla oli kuitenkin suuntaa-antavasti verrokkeja alhaisemmat her\u00e4tevasteet kaikilla aivoalueilla riippumatta tarkkaavuuden suuntaamisesta. T\u00e4m\u00e4 saattaisi antaa viitteit\u00e4 siit\u00e4, ett\u00e4 masentuneilla olisi yleisesti ottaen alhaisemmat sensorisen tiedon vasteet. Tulokset eiv\u00e4t kuitenkaan olleet merkitsevi\u00e4 eik\u00e4 niiden perusteella voida tehd\u00e4 liian suoria johtop\u00e4\u00e4t\u00f6ksi\u00e4. T\u00e4m\u00e4 kuitenkin vahvistaa sit\u00e4, ett\u00e4 tietoa tarvitaan yh\u00e4 lis\u00e4\u00e4 masennuksen ja interoseption yhteydest\u00e4, sek\u00e4 eksteroseption merkityksest\u00e4 masennuksessa. T\u00e4m\u00e4 voisi auttaa ymm\u00e4rt\u00e4m\u00e4\u00e4n paremmin masennuksen oireita sek\u00e4 on t\u00e4rke\u00e4\u00e4 masennuksen hoitomuotojen kehitt\u00e4misen kannalta.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Major depressive disorder (MDD) is one of the largest public health problems. It has major human and economic impacts. MDD can lead to a variety of mental and physical symptoms. Interoception refers to the sense of internal bodily stimuli, for instance heartbeat. The body sense may partly explain how the current body state can influence mental processes, such as subjective feelings. Many psychiatric disorders, including MDD, are considered to be associated with interoceptive sensitivity and its abnormalities. Interoceptive signals cause measurable brain responses. These have been studied very little in depressed individuals. In this study, we examined interoceptive sensitivity in depressed individuals and healthy control volunteers using the heartbeat perception task. The participants had to discriminate whether the sound was synchronous with their heart tone. Furthermore, we studied using magnetoencephalography (MEG), whether depressed and control individuals differ in heartbeat-evoked brain potentials in temporal lobes, parietal lobes and vertex during the interoceptive task. Focusing attention on an auditory sound stimulus was used as a control condition. Depressed individuals did not differ significantly from the control group either in interoceptive sensitivity or heartbeat-evoked brain potentials. Depressed participants had, however, directionally lower brain responses than controls in all the brain areas regardless of the attentional focus. This could possibly refer to the generally lower level of sensory responses in depressed individuals. Nevertheless, the results were not significant and thus, has to be interpreted carefully. This confirms that more information is needed about interoception in depression and also the significance of exteroception in depression. It could help understand better the symptoms and would be important when developing treatment for MDD.", "language": "en", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by Paivi Vuorio (paelvuor@jyu.fi) on 2020-01-08T11:42:04Z\nNo. of bitstreams: 0", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2020-01-08T11:42:05Z (GMT). No. of bitstreams: 0\n Previous issue date: 2019", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "39", "language": "", "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.format.mimetype", "value": "application/pdf", "language": null, "element": "format", "qualifier": "mimetype", "schema": "dc"}, {"key": "dc.language.iso", "value": "fin", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.title", "value": "Masennuksen yhteys syd\u00e4men sykkeen tunnistamiseen ja sen vaikutus aivojen her\u00e4tevasteisiin", "language": "", "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", "value": "master thesis", "language": null, "element": "type", "qualifier": null, "schema": "dc"}, {"key": "dc.identifier.urn", "value": "URN:NBN:fi:jyu-202001081088", "language": "", "element": "identifier", "qualifier": "urn", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Pro gradu -tutkielma", "language": "fi", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Master\u2019s thesis", "language": "en", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Kasvatustieteiden ja psykologian tiedekunta", "language": "fi", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Faculty of Education and Psychology", "language": "en", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Psykologian laitos", "language": "fi", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Department of Psychology", "language": "en", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "Jyv\u00e4skyl\u00e4n yliopisto", "language": "fi", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "University of Jyv\u00e4skyl\u00e4", "language": "en", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Psykologia", "language": "fi", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Psychology", "language": "en", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "yvv.contractresearch.funding", "value": "0", "language": "", "element": "contractresearch", "qualifier": "funding", "schema": "yvv"}, {"key": "dc.type.coar", "value": "http://purl.org/coar/resource_type/c_bdcc", "language": null, "element": "type", "qualifier": "coar", "schema": "dc"}, {"key": "dc.rights.accesslevel", "value": "openAccess", "language": null, "element": "rights", "qualifier": "accesslevel", "schema": "dc"}, {"key": "dc.type.publication", "value": "masterThesis", "language": null, "element": "type", "qualifier": "publication", "schema": "dc"}, {"key": "dc.subject.oppiainekoodi", "value": "202", "language": "", "element": "subject", "qualifier": "oppiainekoodi", "schema": "dc"}, {"key": "dc.subject.yso", "value": "masennus", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "sensitiivisyys", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "signaalit", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "MEG", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.format.content", "value": "fulltext", "language": null, "element": "format", "qualifier": "content", "schema": "dc"}, {"key": "dc.rights.url", "value": "https://rightsstatements.org/page/InC/1.0/", "language": null, "element": "rights", "qualifier": "url", "schema": "dc"}, {"key": "dc.type.okm", "value": "G2", "language": null, "element": "type", "qualifier": "okm", "schema": "dc"}]
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