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[{"key": "dc.contributor.advisor", "value": "Tarkka, Ina", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.advisor", "value": "Pitk\u00e4niemi, Janne", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Yl\u00f6stalo, Tiina", "language": "", "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2019-12-12T08:10:01Z", "language": null, "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2019-12-12T08:10:01Z", "language": null, "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2019", "language": "", "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/66762", "language": null, "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Liikunnalla tiedet\u00e4\u00e4n olevan positiivisia vaikutuksia v\u00e4est\u00f6n terveydelle. Monet tutkimukset ovat osoittaneet liikunnan v\u00e4hent\u00e4v\u00e4n sy\u00f6v\u00e4n sairastumisriski\u00e4. Vahvaa tieteellist\u00e4 n\u00e4ytt\u00f6\u00e4 on liikunnan ennaltaehk\u00e4isev\u00e4st\u00e4 vaikutuksesta rinta-, paksusuoli- ja kohdunrunkosy\u00f6pien riskiin. Vain harvoissa tutkimuksissa on kuitenkin selvitetty, kuinka elinik\u00e4inen fyysinen aktiivisuus on yhteydess\u00e4 sy\u00f6p\u00e4riskiin. T\u00e4m\u00e4n tutkimuksen tarkoituksena on tutkia miten elinik\u00e4inen vapaa-ajan liikunta on yhteydess\u00e4 sy\u00f6p\u00e4riskiin. \nTutkimusaineistona k\u00e4ytettiin Kainuun elintavat ja terveystutkimuksen aineistoa, joka on k\u00e4ynnistetty UKK-instituutissa vuonna 1980. Aineisto koostuu vuosina 1961\u201360 syntyneiden kyselytutkimuksen tiedoista, joille l\u00e4hetettiin ensimm\u00e4inen postikysely vuonna 1980 (n=5259). Tutkimushenkil\u00f6iden elintapoja sek\u00e4 terveydentilaa on seurattu seurantakyselyin vuosina 1981 (n=4602), 1985 (n=4333), 1990 (n=4267) ja 2002 (n=2920). Tutkimushenkil\u00f6i-den sy\u00f6p\u00e4tiedot haettiin Suomen Sy\u00f6p\u00e4rekisterist\u00e4. Tutkimuskohorttia seurattiin vuoden 2017 loppuun saakka. Elinik\u00e4isen vapaa-ajan liikunnan vaikutusta sy\u00f6p\u00e4riskiin analysoitiin Coxin regressiomallia aikariippuvia kovariaatteja k\u00e4ytt\u00e4en. \nEniten vapaa-ajalla liikkuvilla havaittiin olevan 27 % pienentynyt riski sairastua sy\u00f6p\u00e4\u00e4n verrattuna v\u00e4hiten liikkuviin. Kun otettiin huomioon sekoittavat tekij\u00e4t, laski suojaava vaikutus 15 prosenttiin (HR: 0,85, 95% CI: 0,70\u20131,03). Vapaa-ajalla paljon liikkuvilla oli pienempi riski sairastua hengitysteiden sy\u00f6piin (HR: 0,12, 95% CI: 0,05\u20130,39), eturauhassy\u00f6p\u00e4\u00e4n (HR: 0,55 , 95% CI: 0,35\u20130,87) ja naisten rintasy\u00f6p\u00e4\u00e4n, joka on diagnosoitu 60 ik\u00e4vuoden j\u00e4lkeen (HR: 0,45, 95% CI: 0,22\u20130,92). Mallin adjustoimisen j\u00e4lkeen vapaa-ajan liikunnan suojavaikutus oli havaittavissa en\u00e4\u00e4 vain hengityselinten sy\u00f6viss\u00e4 (HR: 0,23, 95% CI: 0,08\u20130,65). Painoindeksin ja vapaa-ajan liikunnan yhdysvaikutus havaittiin v\u00e4hent\u00e4v\u00e4n naisten sukupuolielinten sy\u00f6p\u00e4riski\u00e4 ja naisten rintasy\u00f6p\u00e4riski\u00e4, joka oli diagnosoitu 60 ik\u00e4vuoden j\u00e4lkeen. N\u00e4m\u00e4 yhteydet olivat tilastollisesti merkitsevi\u00e4 sekoittavien tekij\u00f6iden huomion ottamisen j\u00e4lkeenkin. \nSuurempi vapaa-ajan liikunnan m\u00e4\u00e4r\u00e4 v\u00e4hent\u00e4\u00e4 sy\u00f6p\u00e4riski\u00e4, etenkin hengityselinten sy\u00f6p\u00e4riski\u00e4. Painoindeksin ja vapaa-ajan liikunnan yhdysvaikutus on yhteydess\u00e4 naisten sukupuolielinten sy\u00f6p\u00e4riskiin sek\u00e4 rintasy\u00f6p\u00e4riskiin, joka on diagnosoitu 60 ik\u00e4vuoden j\u00e4lkeen.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Physical activity is known to have a positive effect on the population health. Many studies have shown that physical activity reduces the risk of cancer. There are strong evidence of the preventive effect of physical activity on the risk of breast, colon and endometrial cancers. However, only a few studies have explored how lifelong physical activity affects cancer risk. The aim of this study is to assess the effect of lifelong exposure and changes in leisure-time physical activity (LTPA) with respect to the risk of any primary cancer.\nThe study material is based on a systematic representative sample from the Kainuu Study of living Habits and Health (KETTU-study) which began in 1980. A self-administered questionnaire included questions about health behavior, living habits and socioeconomic background factors. In 1980 surveys were send to 6787 northeastern Finns between ages 19 and 63. There were 5259 respondents to the surveys baseline questionnaires. Follow-up questionnaires were sent in 1981 (n=4 602), 1985 (n=4 333), 1996 (n=4 267) and 2001 (n=2 920). The study cohort was followed until the end of 2017. Cancer cases were identified from the Finnish Cancer Registry and mortality data was obtained from Statistics Finland. The Cox proportional-hazards regression model for time-dependent covariates was used to estimate how lifelong physical activity is associated with cancer. \nAfter comparing higher level of LTPA to lower level of LTPA the impact of physical activity showed 27 % reduced risk for overall cancer. The respective adjusted HR indicated a 15 % reduction (HR: 0.85, 95 % CI: 0.70-1.03). Higher level of leisure-time physical activity was associated with a lower risk for respiratory organs cancer (low PA vs high PA, HR: 0.12, 95 % CI: 0.05-0.39), prostate (low PA vs high PA, HR: 0.55, 95 % CI: 0.35-0.87) and female breast cancer diagnosed post-age-60 (low PA vs middle PA, HR: 0.45, 95 % CI: 0.22-0.92). After adjusting the model the protective effect of LTPA was statistically significant only for respiratory organs cancer (HR: 0.23, 95 % CI: 0.08-0.65). Interaction between BMI and LTPA was found to reduce the risk for female genital organs cancer and female breast cancer diagnosed post-age-60. These associations were statistically significant after the adjustment.\nHigher leisure-time physical activity reduces the risk of some cancer types especially for respiratory organs cancer. Interaction between BMI and leisure-time physical activity is association with female cancer risk; female genital organs cancer and breast cancer diagnosed after age 60.", "language": "en", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by Paivi Vuorio (paelvuor@jyu.fi) on 2019-12-12T08:10:01Z\nNo. of bitstreams: 0", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2019-12-12T08:10:01Z (GMT). No. of bitstreams: 0\n Previous issue date: 2019", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "41", "language": "", "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.format.mimetype", "value": "application/pdf", "language": null, "element": "format", "qualifier": "mimetype", "schema": "dc"}, {"key": "dc.language.iso", "value": "fin", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.subject.other", "value": "aikariippuva kovariaatti", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.title", "value": "Elinik\u00e4isen vapaa-ajan liikunnan yhteys sy\u00f6p\u00e4riskiin", "language": "", "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", "value": "master thesis", "language": null, "element": "type", "qualifier": null, "schema": "dc"}, {"key": "dc.identifier.urn", "value": "URN:NBN:fi:jyu-201912125224", "language": "", "element": "identifier", "qualifier": "urn", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Pro gradu -tutkielma", "language": "fi", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Master\u2019s thesis", "language": "en", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Liikuntatieteellinen tiedekunta", "language": "fi", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Faculty of Sport and Health Sciences", "language": "en", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Liikunta- ja terveystieteet", "language": "fi", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Sport and Health Sciences", "language": "en", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "Jyv\u00e4skyl\u00e4n yliopisto", "language": "fi", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "University of Jyv\u00e4skyl\u00e4", "language": "en", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Liikuntal\u00e4\u00e4ketiede", "language": "fi", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Sport Medicine", "language": "en", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "yvv.contractresearch.funding", "value": "0", "language": "", "element": "contractresearch", "qualifier": "funding", "schema": "yvv"}, {"key": "dc.type.coar", "value": "http://purl.org/coar/resource_type/c_bdcc", "language": null, "element": "type", "qualifier": "coar", "schema": "dc"}, {"key": "dc.rights.accesslevel", "value": "restrictedAccess", "language": null, "element": "rights", "qualifier": "accesslevel", "schema": "dc"}, {"key": "dc.type.publication", "value": "masterThesis", "language": null, "element": "type", "qualifier": "publication", "schema": "dc"}, {"key": "dc.subject.oppiainekoodi", "value": "5042", "language": "", "element": "subject", "qualifier": "oppiainekoodi", "schema": "dc"}, {"key": "dc.subject.yso", "value": "elintavat", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "painoindeksi", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "sy\u00f6p\u00e4taudit", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "fyysinen aktiivisuus", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "breast cancer", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "activity", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.format.content", "value": "fulltext", "language": null, "element": "format", "qualifier": "content", "schema": "dc"}, {"key": "dc.rights.url", "value": "https://rightsstatements.org/page/InC/1.0/", "language": null, "element": "rights", "qualifier": "url", "schema": "dc"}, {"key": "dc.rights.accessrights", "value": "The author has not given permission to make the work publicly available electronically. Therefore the material can be read only at the archival workstation at Jyv\u00e4skyl\u00e4 University Library (https://kirjasto.jyu.fi/en/workspaces/facilities).", "language": "en", "element": "rights", "qualifier": "accessrights", "schema": "dc"}, {"key": "dc.rights.accessrights", "value": "Tekij\u00e4 ei ole antanut lupaa avoimeen julkaisuun, joten aineisto on luettavissa vain Jyv\u00e4skyl\u00e4n yliopiston kirjaston arkistoty\u00f6semalta. Ks. https://kirjasto.jyu.fi/fi/tyoskentelytilat/laitteet-ja-tilat..", "language": "fi", "element": "rights", "qualifier": "accessrights", "schema": "dc"}, {"key": "dc.type.okm", "value": "G2", "language": null, "element": "type", "qualifier": "okm", "schema": "dc"}]
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