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[{"key": "dc.contributor.advisor", "value": "Juutinen, Taija", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Rikkonen, Eero", "language": null, "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2017-12-19T20:42:06Z", "language": "", "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2017-12-19T20:42:06Z", "language": "", "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2017", "language": null, "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.other", "value": "oai:jykdok.linneanet.fi:1809985", "language": null, "element": "identifier", "qualifier": "other", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/56444", "language": "", "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Ik\u00e4\u00e4ntymisen my\u00f6t\u00e4 luustolihaksen toiminta muuttuu ja lihasmassa v\u00e4henee. Ik\u00e4\u00e4ntymisen vaikutukset eroavat naisten ja miesten v\u00e4lill\u00e4. Estrogeenituotannon v\u00e4henemist\u00e4 pidet\u00e4\u00e4n er\u00e4\u00e4n\u00e4 osatekij\u00e4n\u00e4 naisten suorituskyvyn laskun kiihtymiselle, joka ajoittuu vaihdevuosien yhteyteen. Vaikka estrogeenin vaikutusmekanismia lihasten toiminnassa ei tunnetakaan kovin hyvin, on viitteit\u00e4, ett\u00e4 estrogeenin vaikutus kohdistuu myosiinimolekyylin fosforylaatioon. Myosiinifosforylaatiolla on merkitt\u00e4v\u00e4 rooli lihasaktivaation j\u00e4lkeisess\u00e4 voimantuoton potentoitumisessa (PAP). PAP:lla tarkoitetaan ilmi\u00f6t\u00e4, jossa lihaksen aiempi supistus vaikuttaa lihaksen voimantuottoon. T\u00e4m\u00e4n tutkimuksen tarkoituksena oli selvitt\u00e4\u00e4, vaikuttaako estrogeenivaje lihasaktivaation j\u00e4lkeiseen voimantuoton potentoitumiseen.\r\nT\u00e4m\u00e4 tutkimus oli osa laajempaa ERMA-tutkimusprojektia. Tutkimukseen valikoitui 32 48-54-vuotiasta naista, jotka osallistuivat alkumittauksiin ennen vaihdevuosien alkua. Loppumittaukset suoritettiin, kun naisten vaihdevuosien todettiin p\u00e4\u00e4ttyneen sukupuolihormonitasojen perusteella. Tutkittavien lihasaktivaation j\u00e4lkeist\u00e4 potentoitumista mitattiin sek\u00e4 s\u00e4hk\u00f6isesti aiheutetun ett\u00e4 tahdonalaisen voimantuoton osalta nilkan ojennusteht\u00e4v\u00e4ss\u00e4. S\u00e4hk\u00f6isesti aiheutetun voimantuoton potentoitumista arvioitiin vertaamalla s\u00e4hk\u00f6stimulaatiolla aiheutetun yksitt\u00e4isen lihasnyk\u00e4yksen voimaa ennen ja j\u00e4lkeen maksimaalisen tahdonalaisen supistuksen. Tahdonalaista voimantuoton potentoitumista tutkittiin maksimaalisen voimantuoton ja voimantuottonopeuden avulla. Lis\u00e4ksi tutkittiin tahdonalaisen lihasaktivaation muutosta alku- ja loppumittausten v\u00e4lill\u00e4.\r\nTulokset antoivat viitteit\u00e4 estrogeenivajeen negatiivisesta vaikutuksesta voimantuoton potentoitumiseen, mutta muutokset eiv\u00e4t olleet tilastollisesti merkitsevi\u00e4. Ei-tahdonalaisen voimantuoton potentoituminen yksitt\u00e4isen tahdonalaisen supistuksen vaikutuksesta oli alkumittauksissa 4,5 % ja loppumittauksissa -1,0 %. Tahdonalaisen voimantuoton osalta potentoituminen oli alkumittauksissa 11 % ja loppumittauksissa 3,8 %. Tutkimuksen perusteella ei voitu varmuudella todeta yhteytt\u00e4 tutkittavien voimantuoton potentoitumisen ja estrogeenivajeen v\u00e4lill\u00e4 niin ei-tahdonalaisessa kuin tahdonalaisessa tilanteessa. Estrogeenivajeella ei havaittu yhteytt\u00e4 tahdonalaiseen aktivaatiotasoon. Sek\u00e4 alku- ett\u00e4 loppumittauksissa aktivaatiotaso oli 77 %. Mahdollisissa jatkotutkimuksissa tulisi kiinnitt\u00e4\u00e4 huomiota potentoivan lihassupistuksen riitt\u00e4v\u00e4\u00e4n intensiteettiin ja kestoon oletetun potentoitumisen maksimoimiseksi. My\u00f6s potentoitumisvaikutuksen aikaprofiilin muodostaminen olisi hy\u00f6dyllist\u00e4.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted using Plone Publishing form by Eero Rikkonen (eealrikk) on 2017-12-19 20:42:04.341203. Form: Pro gradu -lomake (https://kirjasto.jyu.fi/julkaisut/julkaisulomakkeet/pro-gradu-lomake). JyX data: [jyx_publishing-allowed (fi) =True]", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by jyx lomake-julkaisija (jyx-julkaisija.group@korppi.jyu.fi) on 2017-12-19T20:42:06Z\r\nNo. of bitstreams: 2\r\nURN:NBN:fi:jyu-201712194797.pdf: 745148 bytes, checksum: f559c0f9d7332342c3d3d5e128a3e937 (MD5)\r\nlicense.html: 4840 bytes, checksum: 680afb6d7148e03fc0e79cae6db816ed (MD5)", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2017-12-19T20:42:06Z (GMT). No. of bitstreams: 2\r\nURN:NBN:fi:jyu-201712194797.pdf: 745148 bytes, checksum: f559c0f9d7332342c3d3d5e128a3e937 (MD5)\r\nlicense.html: 4840 bytes, checksum: 680afb6d7148e03fc0e79cae6db816ed (MD5)\r\n Previous issue date: 2017", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "1 verkkoaineisto (52 sivua)", "language": null, "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.format.mimetype", "value": "application/pdf", "language": null, "element": "format", "qualifier": "mimetype", "schema": "dc"}, {"key": "dc.language.iso", "value": "fin", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.subject.other", "value": "biomekaniikka", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": 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