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[{"key": "dc.contributor.advisor", "value": "Astikainen, Piia", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Heikura, Emma", "language": null, "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Lilja, Margareetta", "language": null, "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2017-08-16T19:13:41Z", "language": "", "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2017-08-16T19:13:41Z", "language": "", "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2017", "language": null, "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.other", "value": "oai:jykdok.linneanet.fi:1719651", "language": null, "element": "identifier", "qualifier": "other", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/55126", "language": "", "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Nuorten (n=17, i\u00e4n vaihteluv\u00e4li 20-27) ja ik\u00e4\u00e4ntyvien (n=15, i\u00e4n vaihteluv\u00e4li 65-75) aivovasteita s\u00e4hk\u00f6isten \u00e4rsykkeiden sijaintimuutoksiin mitattiin aivomagneettik\u00e4yr\u00e4ll\u00e4 (MEG) aktiivisessa ja passiivisessa tutkimusasetelmassa. My\u00f6hemmin osallistujat suorittivat sarjan neurokognitiivisia testej\u00e4. Aikaisen latenssin aisti\u00e4rsykkeiden suodattamiseen liittyvien aivovasteiden amplitudeja (M50 ja M100) ja eroavuuden havaitsemiseen, \u00e4rsykkeisiin orientoitumiseen ja kohteiden tunnistamiseen liittyvi\u00e4 my\u00f6hempi\u00e4 aivovasteita (MMR, M200 ja M300) analysoitiin ja vertailtiin ik\u00e4ryhmien v\u00e4lill\u00e4.\r\n M100 amplitudissa oli havaittavissa merkitt\u00e4v\u00e4\u00e4 vaimentumista standardi\u00e4rsykkeiden kohdalla nuorten aikuisten ryhm\u00e4ss\u00e4. Ik\u00e4\u00e4ntyvien aikuisten ryhm\u00e4ss\u00e4 vaimentumista ei tapahtunut aisti\u00e4rsykkeiden suodattamisen kapasiteetissa tapahtuvien ik\u00e4\u00e4ntymismuutosten vuoksi. Neurokognitiivisissa testeiss\u00e4 suoriutumisen riippuvuutta M50 ja M100 vasteiden amplitudeista ja latensseista tarkasteltiin Pearsonin korrelaatiokertoimella. Merkitsev\u00e4t korrelaatiot antavat tentatiivista tukea prosessointinopeuden ja eksekutiivisen kontrollin sek\u00e4 M100 amplitudin ja ty\u00f6muistikapasiteetin v\u00e4lisest\u00e4 yhteydest\u00e4 nuorilla aikuisilla.\r\n MMR ja M300 komponenttien amplitudit olivat pienempi\u00e4 ik\u00e4\u00e4ntyvill\u00e4 aikuisilla passiivisessa tutkimusasetelmassa, mik\u00e4 vahvistaa k\u00e4sityst\u00e4 eroavuuden havaitsemisessa tapahtuvasta ik\u00e4\u00e4ntymiseen liittyv\u00e4st\u00e4 heikentymisest\u00e4. Merkitt\u00e4vi\u00e4 eroja aktiivisen tutkimusasetelman M200 tai M300 vasteissa ei ollut havaittavissa ryhmien v\u00e4lill\u00e4. Mahdollinen selitys havainnoille on, ett\u00e4 aktiivinen tarkkaavuus voi kompensoida ik\u00e4\u00e4ntymismuutoksia kognitiivisissa kyvyiss\u00e4. Korrelaatiot MMR, M200 ja M300 vasteiden ja kognitiivisten testien v\u00e4lill\u00e4 osoittivat yhteyden eroavuuden havaitsemisen ja ty\u00f6muistikapasiteetin sek\u00e4 eroavuuden havaitsemisen ja eksekutiivisen kontrollin v\u00e4lill\u00e4 nuorten aikuisten ryhm\u00e4ss\u00e4.\r\n Heikentyv\u00e4 aisti\u00e4rsykkeiden suodattamisen ja muutoksenhavaitsemisen kyky kuuluu terveeseen ik\u00e4\u00e4ntymiseen ja on havaittavissa somatosensoristen \u00e4rsykkeiden aikaansaamissa aivovasteissa ennen kuin ik\u00e4\u00e4ntymismuutokset ovat havaittavissa k\u00e4yt\u00f6ksen tasolla. Aktiivinen tarkkaavuus kompensoi ik\u00e4\u00e4ntymiseen liittyv\u00e4\u00e4 heikentymist\u00e4 kognitiivisissa toiminnoissa.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.abstract", "value": "The present study recorded somatosensory evoked fields (SEFs) with magnetoencephalography (MEG) to changes in location of electrical pulses of young (n=17, age range 20-27) and older (n=15, age range 65-75) adults. The participants were presented with rapid changes in stimulus location to which they were instructed to either attend or not attend to. They subsequently completed a series of cognitive tests. SEF components associated with sensory gating (M50 and M100) and change detection, stimulus orientation and target recognition (MMR, M200, M300) were analyzed and compared between groups. \r\n A significant attenuation in M100 amplitude was observed in response to the standard stimulus for young adults but not for older adults owing to age-related weakening of sensory gating. Pearson\u2019s correlation coefficient was used to measure the correlation between the amplitudes and latencies of M50 and M100 and performance in neuropsychological tests in both groups. A correlation between early measures of processing speed and executive control and an association between M100 amplitude and working sensory memory for young adults was obtained.\r\n MMR and M300 amplitudes were attenuated in the older adults group but not among young adults suggesting weakening change detection and target recognition capacity in aging. No significant differences in the attended M200 or M300 were observable between groups perhaps due to the compensatory role of active aging in age-related cognitive decline. Correlations between MMR, M200 and M300 responses and performance in neuropsychological tests suggested a connection between active change detection and working memory performance and passive change detection and executive control but only for young adults. \r\n Healthy aging appears to be accompanied by weakening sensory gating and change detection capacity which may be observable using somatosensory evoked fields before age-related cognitive decline becomes apparent behaviorally. Active attention may compensate for age-related weakening in cognitive capacity.", "language": "en", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted using Plone Publishing form by Emma Heikura (empaheik) on 2017-08-16 19:13:40.794355. Form: Pro gradu -lomake (https://kirjasto.jyu.fi/julkaisut/julkaisulomakkeet/pro-gradu-lomake). JyX data: [jyx_publishing-allowed (fi) =False]", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by jyx lomake-julkaisija (jyx-julkaisija.group@korppi.jyu.fi) on 2017-08-16T19:13:41Z\r\nNo. of bitstreams: 2\r\nURN:NBN:fi:jyu-201708163506.pdf: 890025 bytes, checksum: 8c74138a1e78ec02bcd3852520d6252c (MD5)\r\nlicense.html: 1155 bytes, checksum: 2704db3162634db1782ed261b8c1cae5 (MD5)", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2017-08-16T19:13:41Z (GMT). No. of bitstreams: 2\r\nURN:NBN:fi:jyu-201708163506.pdf: 890025 bytes, checksum: 8c74138a1e78ec02bcd3852520d6252c (MD5)\r\nlicense.html: 1155 bytes, checksum: 2704db3162634db1782ed261b8c1cae5 (MD5)\r\n Previous issue date: 2017", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "1 verkkoaineisto (39 sivua)", "language": null, "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.format.mimetype", "value": "application/pdf", "language": null, "element": "format", "qualifier": "mimetype", "schema": "dc"}, {"key": "dc.language.iso", "value": "eng", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.subject.other", "value": "aging", "language": null, "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "healthy aging", "language": null, "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "aging brain", "language": null, "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "somatosensory evoked fields", "language": null, "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "MMR", "language": null, "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.title", "value": "Somatosensory evoked fields and cognitive functioning in healthy aging", "language": null, "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", "value": "master thesis", "language": null, "element": "type", "qualifier": null, "schema": "dc"}, {"key": "dc.identifier.urn", "value": "URN:NBN:fi:jyu-201708163506", "language": null, "element": "identifier", "qualifier": "urn", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Pro gradu 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Aineisto on luettavissa Jyv\u00e4skyl\u00e4n yliopiston kirjaston arkistoty\u00f6asemalta. Ks. https://kirjasto.jyu.fi/fi/tyoskentelytilat/laitteet-ja-tilat.", "language": "fi", "element": "rights", "qualifier": "accessrights", "schema": "dc"}, {"key": "dc.rights.accessrights", "value": "This material has a restricted access due to copyright reasons. It can be read at the workstation at Jyv\u00e4skyl\u00e4 University Library reserved for the use of archival materials: https://kirjasto.jyu.fi/en/workspaces/facilities.", "language": "en", "element": "rights", "qualifier": "accessrights", "schema": "dc"}, {"key": "dc.type.okm", "value": "G2", "language": null, "element": "type", "qualifier": "okm", "schema": "dc"}]
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