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[{"key": "dc.contributor.advisor", "value": "Pirhonen, Juhani", "language": null, "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Piiroinen, Laura", "language": null, "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2016-06-24T18:22:01Z", "language": null, "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2016-06-24T18:22:01Z", "language": null, "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2016", "language": null, "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.other", "value": "oai:jykdok.linneanet.fi:1545331", "language": null, "element": "identifier", "qualifier": "other", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/50590", "language": null, "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Kalanrehuissa on perinteisesti luotettu kalajauhoon ja -\u00f6ljyyn rehujen p\u00e4\u00e4asiallisina proteiinin- ja energianl\u00e4htein\u00e4. N\u00e4it\u00e4 raaka-aineita on nyky\u00e4\u00e4n alettu korvata kasviper\u00e4isill\u00e4 ainesosilla niiden edullisemman hinnan ja helpomman saatavuuden vuoksi, esimerkiksi maissilla, vehn\u00e4ll\u00e4 ja soijalla. Pilaantuneen kasviper\u00e4isen raaka-aineen mukana rehuun p\u00e4\u00e4see haitallisia mykotoksiineja. Mykotoksiinit ovat homesienten sekund\u00e4\u00e4risi\u00e4 metaboliatuotteita, joita ne p\u00e4\u00e4asiassa tuottavat kilpailuun muita homeita vastaan, ja joiden on havaittu aiheuttavan kasvun heikentymist\u00e4 ja sairauksia monilla eri kotiel\u00e4imill\u00e4, mutta niiden vaikutuksista kaloihin tiedet\u00e4\u00e4n varsin v\u00e4h\u00e4n. Yksi yleisimmist\u00e4 mykotoksiineista on p\u00e4\u00e4asiassa maissilla esiintyv\u00e4n Fusarium moniliforme -homeen tuottama fumonisiini B1 (FB1). T\u00e4ss\u00e4 tutkimuksessa tutkittiin rehun sis\u00e4lt\u00e4m\u00e4n FB1:n vaikutusta kirjolohen (Oncorhynchus mykiss) kasvuun ja fysiologiaan. 1+ -ik\u00e4iset kirjolohet jaettiin satunnaisesti koeryhmiin, joita ruokittiin kasvatuskokeessa kahdeksan viikon ajan rehulla, johon oli lis\u00e4tty viisi eri FB1 -pitoisuutta: 0, 1, 5, 10 ja 20 mg/kg. Kalojen kasvua ja rehunkulutusta seurattiin kokeen aikana. Kokeen j\u00e4lkeen kaloista otettiin verin\u00e4ytteet, joista analysoitiin hematokriitti, glukoosipitoisuus ja plasman kloridipitoisuus. Kalojen maksoista tutkittiin painojen ohella niiden vesipitoisuus. Osasta maksoista valmistettiin leikkeet mahdollisten histopatologisten poikkeamien havaitsemiseksi. Tulokset osoittivat, ettei FB1 vaikuttanut kalojen kasvuun, niiden veriarvoihin tai maksoihin annetuilla pitoisuuksilla. Kirjolohi on herkk\u00e4 kahdelle muulle mykotoksiinille, deoksinivalenolille ja aflatoksiinille, mutta laji vaikuttaa kest\u00e4v\u00e4n FB1:t\u00e4 varsin hyvin. T\u00e4m\u00e4 voi johtua erilaisista solutason aineenvaihdunnan reiteist\u00e4 ja biotransformaation eroista mykotoksiinien v\u00e4lill\u00e4. Kuitenkin lis\u00e4tutkimuksia pitemmill\u00e4 altistusajoilla ja/tai suuremmilla FB1 -pitoisuuksilla tarvitaan havaitsemaan mahdolliset vaikutukset kirjoloheen.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Traditionally, fish meal and fish oil have been used as main sources of proteins and energy in the commercial fish feeds. Nowadays these ingredients have been partially substituted with materials of plant-origin (e.g. maize, wheat and soy) due to their more inexpensive price and easier availability. If contaminated plant material is used in the making of fish feed, the finished product can contain harmful substances called mycotoxins. Mycotoxins are the secondary metabolite products of moulds that are produced mainly for competition against other moulds. Feed mycotoxins have been observed to suppress growth and cause diseases on several domestic animals, but their effects on fish have been studied scarcely. One of the most common mycotoxins is fumonisin B1 (FB1) produced by fungus Fusarium moniliforme. FB1 contaminates mainly maize and maize products. In this 8-week study, the effects of dietary FB1 on the growth and physiology of juvenile rainbow trout (Oncorhynchus mykiss) were examined. The fish were divided randomly into treatment groups that were fed with graded concentrations of FB1: 0, 1, 5, 10 or 20 mg/kg. The growth of the fish and the feed consumption was monitored during the trial. After the trial, the blood samples of the fish were analysed for haematocrit, glucose and plasma chloride, and hepatosomatic index and liver water content were measured. Samples were taken from livers to examine possible histopathological abnormalities. The results indicate that FB1 does not affect growth, haematology or livers of rainbow trout at tested concentrations. Rainbow trout is known to be sensitive towards mycotoxins deoxynivalenol and aflatoxin, but appears more resistant towards FB1. This is maybe due to different metabolic pathways at cellular level and differences in biotransformation between different toxins. However, a longer experiment and/or increased amounts of FB1, may be needed to track possible adverse effects of FB1 on rainbow trout.", "language": "en", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted using Plone Publishing form by Laura Piiroinen (lamapiir) on 2016-06-24 18:22:00.629428. Form: Pro gradu -lomake (https://kirjasto.jyu.fi/julkaisut/julkaisulomakkeet/pro-gradu-lomake). JyX data: [jyx_publishing-allowed (fi) =True]", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by jyx lomake-julkaisija (jyx-julkaisija.group@korppi.jyu.fi) on 2016-06-24T18:22:01Z\nNo. of bitstreams: 2\nURN:NBN:fi:jyu-201606243346.pdf: 959693 bytes, checksum: 1593f40bda94664ed7733f91c90dcdd0 (MD5)\nlicense.html: 4859 bytes, checksum: a966d0fb2dc4664dfad9ed6719ac2b77 (MD5)", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2016-06-24T18:22:01Z (GMT). No. of bitstreams: 2\nURN:NBN:fi:jyu-201606243346.pdf: 959693 bytes, checksum: 1593f40bda94664ed7733f91c90dcdd0 (MD5)\nlicense.html: 4859 bytes, checksum: a966d0fb2dc4664dfad9ed6719ac2b77 (MD5)\n Previous issue date: 2016", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "1 verkkoaineisto (28 sivua)", "language": null, "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.format.mimetype", "value": "application/pdf", "language": null, "element": "format", "qualifier": "mimetype", "schema": "dc"}, {"key": "dc.language.iso", "value": "eng", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.subject.other", "value": "feedstuff", "language": null, "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "Fusarium moniliforme", "language": null, "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "mycotoxin", "language": null, "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "haematology", "language": null, "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "histology", "language": null, "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "salmonid", "language": null, "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "specific growth rate", "language": null, "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.title", "value": "The effects of dietary fumonisin B1 on growth and physiology of rainbow trout (Oncorhynchus mykiss)", "language": null, "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", 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"department", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Department of Biological and Environmental Science", "language": "en", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "University of Jyv\u00e4skyl\u00e4", "language": "en", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "Jyv\u00e4skyl\u00e4n yliopisto", "language": "fi", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Akvaattiset tieteet", "language": "fi", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Aquatic sciences", "language": "en", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.date.updated", "value": "2016-06-24T18:22:01Z", "language": null, "element": "date", "qualifier": "updated", "schema": "dc"}, 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