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[{"key": "dc.contributor.advisor", "value": "Tarkka, Ina", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.advisor", "value": "Cheng, Sulin", "language": "", "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Lehtonen, Heidi", "language": null, "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2016-06-22T15:51:52Z", "language": "", "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2016-06-22T15:51:52Z", "language": "", "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2016", "language": null, "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.other", "value": "oai:jykdok.linneanet.fi:1545349", "language": null, "element": "identifier", "qualifier": "other", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/50576", "language": "", "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Rintasy\u00f6p\u00e4 on Suomessa naisten yleisin sy\u00f6p\u00e4tauti ja positiivinen sukuhistoria on rintasy\u00f6v\u00e4n merkitt\u00e4vin yksitt\u00e4inen riskitekij\u00e4. Vuonna 2013 Suomessa todettiin 4831 uutta rintasy\u00f6p\u00e4tapausta ja ennuste vuodelle 2027 on noin 6000 uutta tapausta vuosittain. Fyysisesti aktiivisilla naisilla on merkitsev\u00e4sti alentunut riski sairastua rintasy\u00f6p\u00e4\u00e4n. Nuorena ja varhaisaikuisuudessa harrastetulla fyysisell\u00e4 aktiivisuudella on todettu tilastollisesti merkitsev\u00e4 yhteys alentuneeseen rintasy\u00f6v\u00e4n sairastumisriskiin. Fyysisell\u00e4 aktiivisuudella voidaan vaikuttaa my\u00f6s rintasy\u00f6v\u00e4n muihin riskitekij\u00f6ihin, kuten ylipainoon ja hormonaalisiin tekij\u00f6ihin. T\u00e4m\u00e4n tutkimuksen tarkoituksena oli selvitt\u00e4\u00e4, assosioituuko fyysinen aktiivisuus naisten rintasy\u00f6v\u00e4n esiintyvyyteen tutkittavien suvuissa ja eroavatko kehonkoostumukselliset muuttujat tutkittavilla suvun rintasy\u00f6p\u00e4historian kannalta tarkasteltuna.\r\nTutkimusaineistona k\u00e4ytettiin Jyv\u00e4skyl\u00e4n yliopiston vuosina 1999 - 2010 tekem\u00e4n Calex-perhetutkimuksen aineistoa. Saman perheen \u00e4ideille ja tytt\u00e4rille suoritettiin antropometriset mittaukset ja he t\u00e4yttiv\u00e4t terveytt\u00e4- ja elintapoja koskevan terveyskyselyn. Lis\u00e4ksi kartoitettiin tutkittavien sukujen sy\u00f6p\u00e4historia. Tutkittavat luokiteltiin kolmeen luokkaan fyysisen aktiivisuuden frekvenssin ja keston perusteella. Lis\u00e4ksi heid\u00e4t luokiteltiin kahteen luokkaan suvun rintasy\u00f6p\u00e4historian perusteella. Tilastolliset analyysit suoritettiin SPSS Statistic 22 \u2013 ohjelmassa ristiintaulukoinnilla ja ep\u00e4parametrisella Mann-Whitneyn U -testill\u00e4. \r\nT\u00e4ss\u00e4 tutkimuksessa \u00e4ideill\u00e4 18.3%:lla ja tytt\u00e4rill\u00e4 15.4%:lla esiintyi suvussa rintasy\u00f6p\u00e4historiaa. He kuuluivat positiivisen sukuhistorian vuoksi rintasy\u00f6v\u00e4n riskiryhm\u00e4\u00e4n. Tutkittavien sukujen sy\u00f6p\u00e4historiassa oli yleisemp\u00e4\u00e4, ett\u00e4 rintasy\u00f6p\u00e4diagnoosin lis\u00e4ksi esiintyi muitakin sy\u00f6p\u00e4diagnooseja. Tuloksissa fyysisesti aktiivisimmilla tytt\u00e4rill\u00e4 esiintyi suvussa hieman enemm\u00e4n rintasy\u00f6p\u00e4\u00e4 fyysisesti v\u00e4hemm\u00e4n aktiivisiin verrattuna, kun taas \u00e4ideill\u00e4 rintasy\u00f6v\u00e4n esiintyvyys vaikutti suurimmalta kohtalaisesti aktiivisten tutkittavien suvuissa. Tulosten mukaan rintasy\u00f6v\u00e4n esiintyvyys vaihteli ryhmien v\u00e4lill\u00e4, mutta tilastollisesti merkitsevi\u00e4 eroja ei havaittu. Tilastollisesti merkitsev\u00e4\u00e4 eroa ei havaittu my\u00f6sk\u00e4\u00e4n tutkittavien kehonkoostumusten v\u00e4lill\u00e4, kun tarkasteltiin suvun rintasy\u00f6p\u00e4historian mukaan jaoteltuna tutkittavien painoindeksi\u00e4, rasvaprosenttia ja leptiinihormonipitoisuutta. \r\nT\u00e4m\u00e4n tutkimuksen tulosten perusteella fyysisell\u00e4 aktiivisuudella ja kehonkoostumuksellisilla muuttujilla ei havaittu assosiaatioita tutkittavien sukujen rintasy\u00f6v\u00e4n esiintyvyyteen niill\u00e4 tutkittavilla, jotka kuuluivat positiivisen sukuhistorian vuoksi rintasy\u00f6v\u00e4n riskiryhm\u00e4\u00e4n.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Breast cancer is the most common cancer in Finnish women. Positive family history is the single most important riskfactor for breast cancer. In 2013, 4381 new cases of breast cancer were diagnosed and the prediction for 2027 is approximately 6000 new cases each year. Physically active women have a significantly lowered risk of breast cancer. Physical activity during childhood and early adulthood has been found to have a statistically significant association with lowered risk of breast cancer. Physical activity can affect other risk factors of breast cancer as well, such as overweight and hormonal factors. The purpose of this study was to find out whether physical activity is associated with occurence of breast cancer in the families of the subjects and whether factors of body composition in the subjects differ based on the history of breast cancer in their families. \r\n\r\nThe research data used for this study was gathered during the Calex family study conducted at the Jyv\u00e4skyl\u00e4 University of Jyv\u00e4skyl\u00e4 during 1999-2010. Mothers and daughters from the same families were assessed anthropometrically and they completed a questionnaire on health and lifestyle. In addition, the history of cancer in the studied families was recorded out. The subjects were classified into three groups based on frequency and duration of physical activity. In addition, they were classified into two groups based on their family history of breast cancer. Statistical analyses were performed using crosstabulation and nonparametric Mann-Whitney U-test in SPSS Statistic 22. \r\n\r\nIn this study 18.3% of mothers and 15.4% of daughters had familyhistory of breast cancer. Due to positive familyhistory of breast cancer they belonged to high-risk group. According to the results, breast cancer tended to be more common in the families of the physically more active daughters compared to the physically more passive daughters, whereas in mothers the occurence of breast cancer may have been more common in the moderately physically active subjects' families.Though numbers of cases varied somewhat the present groups did not differ statistically. The difference between body composition in the subjects was not statistically significant either, when the body mass index, percentage body fat and amount of leptin hormone in the subjects were studied according to the families' breast cancer history. \r\n\r\nAccording to the results of this study, physical activity and factors of body composition as lifestyle factors do not seem to associate with occurence of breast cancer in the subjects' families breast cancer history neither in mothers nor in daughters who belonged to the risk group of breast cancer due to positive family history.\r\n\r\nKeywords: women, breast cancer, physical activity, body composition, lifestyle", "language": "en", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted using Plone Publishing form by Heidi Lehtonen (heemleht) on 2016-06-22 15:51:51.589099. Form: Pro gradu -lomake (https://kirjasto.jyu.fi/julkaisut/julkaisulomakkeet/pro-gradu-lomake). JyX data: [jyx_publishing-allowed (fi) =True]", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by jyx lomake-julkaisija (jyx-julkaisija.group@korppi.jyu.fi) on 2016-06-22T15:51:52Z\r\nNo. of bitstreams: 2\r\nURN:NBN:fi:jyu-201606223332.pdf: 4001486 bytes, checksum: e4d100cf78083d280515690bc04e88c2 (MD5)\r\nlicense.html: 4866 bytes, checksum: 95d0b9df6391fa78e5ce3cab9454f65d (MD5)", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2016-06-22T15:51:52Z (GMT). No. of bitstreams: 2\r\nURN:NBN:fi:jyu-201606223332.pdf: 4001486 bytes, checksum: e4d100cf78083d280515690bc04e88c2 (MD5)\r\nlicense.html: 4866 bytes, checksum: 95d0b9df6391fa78e5ce3cab9454f65d (MD5)\r\n Previous issue date: 2016", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "1 verkkoaineisto (67 sivua)", "language": null, "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.format.mimetype", "value": "application/pdf", "language": null, "element": "format", "qualifier": "mimetype", "schema": "dc"}, {"key": "dc.language.iso", "value": "fin", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.subject.other", "value": "naiset", "language": "", "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", 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