Event-related potentials to cross-modal stimuli reveal altered sensory gating in aged

Ikääntymisen tiedetään vaikuttavan varhaisiin kognitiivisiin ja havaintotoimintoihin sekä niitä heijastaviin aivojen sähköisiin herätevasteisiin. Sekä kuulo- että tuntojärjestelmässä toistuvan ärsykkeen aikaansaamien varhaisten vasteiden on havaittu olevan ikääntyneillä voimakkaampia kuin nuorilla....

Full description

Bibliographic Details
Main Author: Pentikäinen, Emmi
Other Authors: Yhteiskuntatieteellinen tiedekunta, Faculty of Social Sciences, Psykologian laitos, Department of Psychology, University of Jyväskylä, Jyväskylän yliopisto
Format: Master's thesis
Language:eng
Published: 2015
Subjects:
Online Access: https://jyx.jyu.fi/handle/123456789/48990
_version_ 1828193116050423808
author Pentikäinen, Emmi
author2 Yhteiskuntatieteellinen tiedekunta Faculty of Social Sciences Psykologian laitos Department of Psychology University of Jyväskylä Jyväskylän yliopisto
author_facet Pentikäinen, Emmi Yhteiskuntatieteellinen tiedekunta Faculty of Social Sciences Psykologian laitos Department of Psychology University of Jyväskylä Jyväskylän yliopisto Pentikäinen, Emmi Yhteiskuntatieteellinen tiedekunta Faculty of Social Sciences Psykologian laitos Department of Psychology University of Jyväskylä Jyväskylän yliopisto
author_sort Pentikäinen, Emmi
datasource_str_mv jyx
description Ikääntymisen tiedetään vaikuttavan varhaisiin kognitiivisiin ja havaintotoimintoihin sekä niitä heijastaviin aivojen sähköisiin herätevasteisiin. Sekä kuulo- että tuntojärjestelmässä toistuvan ärsykkeen aikaansaamien varhaisten vasteiden on havaittu olevan ikääntyneillä voimakkaampia kuin nuorilla. Tämä kertoo ikääntyneiden heikommasta kyvystä sulkea pois epäolennaisia ärsykkeitä. Myöhempien vasteiden, kuten poikkeavuusnegatiivisuuden (mismatch negativity, MMN), on havaittu heikkenevän ikääntyneillä. Tässä tutkimuksessa tarkasteltiin ikääntymisen vaikutuksia herätevasteisiin passiivisessa oddball-kokeessa, jossa ärsykkeet muodostuivat kuulo- ja tuntoärsykkeiden yhdistelmistä. Tämän koeasetelman oletettiin tuovan hyvin esille ikääntymiseen liittyvän heikkenemisen kognitiivisissa toiminnoissa, sillä ärsykeyhdistelmien havaitseminen vaatii monimutkaisia kognitiivisia prosesseja. 44 ikääntyneelle (63-79 vuotta) ja 41 nuorelle (20-30 vuotta) koehenkilölle esitettiin toistuvia ärsykkeitä, joiden joukossa esiintyi satunnaisesti säännöstä poikkeavia ärsykkeitä. Kuulo- ja tuntoärsykkeiden yhdistelmät saivat aikaan P50 ja N1 vasteet molemmissa ikäryhmissä, ja ikääntyneiden vasteet olivat voimakkaampia molemmissa vasteissa. Eroja toistuvan ja poikkeavan ärsykkeen välillä ei kuitenkaan havaittu, mikä viittaa siihen, että ärsykeyhdistelmien välisiä eroja ei kyetty havaitsemaan automaattisesti. Tulokset osoittavat, että ikääntyneiden heikentynyt kyky suodattaa pois epäolennaisia ärsykkeitä näkyy myös tilanteessa, jossa ärsykkeet muodostuvat kahden eri aistijärjestelmän ärsykkeiden yhdistelmistä. On mahdollista, että nämä aivojen toiminnan tasolla tapahtuvat muutokset vaikuttavat ikääntyneiden toimintakykyyn arjessa. Event-related potentials (ERPs) reflecting early perceptual and cognitive functions are known to be affected by aging. In both auditory and somatosensory modalities, early responses to repetitive stimuli seem to be enhanced in amplitude in aged participants, indicating declined gating of irrelevant stimuli. On the other hand, later responses, such as the mismatch negativity (MMN), are attenuated compared to young adults. In the present study, the effects of aging on ERPs were investigated in a passive, crossmodal oddball condition, where frequent standard and infrequent deviant stimuli were presented. This stimulus condition was assumed to be effective in revealing aging-related decline in cognitive functions since it requires complex cognitive computations. The responses to auditory-somatosensory stimuli were recorded from 44 aged (63-79 years) and 41 young (20-30 years) participants. The cross-modal stimuli elicited P50 and N1 responses in both age groups, the aged showing larger amplitudes for both responses. However, there were no differences between deviant and standard stimuli. Thus, no MMNs were elicited in either of the groups, suggesting that the cross-modal stimuli could not be differentiated automatically. The results indicate that insufficient sensory gating of multisensory stimuli is evident in aged. It is possible that these changes in brain level affect the functioning of the elderly in their everyday lives.
first_indexed 2024-09-11T08:53:16Z
format Pro gradu
fullrecord [{"key": "dc.contributor.advisor", "value": "Astikainen, Piia", "language": null, "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Pentik\u00e4inen, Emmi", "language": null, "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2016-03-02T09:49:39Z", "language": null, "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2016-03-02T09:49:39Z", "language": null, "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2015", "language": null, "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.other", "value": "oai:jykdok.linneanet.fi:1523725", "language": null, "element": "identifier", "qualifier": "other", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/48990", "language": null, "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Ik\u00e4\u00e4ntymisen tiedet\u00e4\u00e4n vaikuttavan varhaisiin kognitiivisiin ja havaintotoimintoihin sek\u00e4 niit\u00e4 heijastaviin aivojen s\u00e4hk\u00f6isiin her\u00e4tevasteisiin. Sek\u00e4 kuulo- ett\u00e4 tuntoj\u00e4rjestelm\u00e4ss\u00e4 toistuvan \u00e4rsykkeen aikaansaamien varhaisten vasteiden on havaittu olevan ik\u00e4\u00e4ntyneill\u00e4 voimakkaampia kuin\nnuorilla. T\u00e4m\u00e4 kertoo ik\u00e4\u00e4ntyneiden heikommasta kyvyst\u00e4 sulkea pois ep\u00e4olennaisia \u00e4rsykkeit\u00e4. My\u00f6hempien vasteiden, kuten poikkeavuusnegatiivisuuden (mismatch negativity, MMN), on havaittu heikkenev\u00e4n ik\u00e4\u00e4ntyneill\u00e4. T\u00e4ss\u00e4 tutkimuksessa tarkasteltiin ik\u00e4\u00e4ntymisen vaikutuksia her\u00e4tevasteisiin passiivisessa oddball-kokeessa, jossa \u00e4rsykkeet muodostuivat kuulo- ja tunto\u00e4rsykkeiden yhdistelmist\u00e4. T\u00e4m\u00e4n koeasetelman oletettiin tuovan hyvin esille ik\u00e4\u00e4ntymiseen liittyv\u00e4n heikkenemisen kognitiivisissa toiminnoissa, sill\u00e4 \u00e4rsykeyhdistelmien havaitseminen vaatii monimutkaisia kognitiivisia prosesseja. 44 ik\u00e4\u00e4ntyneelle (63-79 vuotta) ja 41 nuorelle (20-30 vuotta) koehenkil\u00f6lle esitettiin toistuvia \u00e4rsykkeit\u00e4, joiden joukossa esiintyi satunnaisesti s\u00e4\u00e4nn\u00f6st\u00e4 poikkeavia \u00e4rsykkeit\u00e4. Kuulo- ja tunto\u00e4rsykkeiden yhdistelm\u00e4t saivat aikaan P50 ja N1 vasteet molemmissa ik\u00e4ryhmiss\u00e4, ja ik\u00e4\u00e4ntyneiden vasteet olivat voimakkaampia molemmissa vasteissa. Eroja toistuvan ja poikkeavan \u00e4rsykkeen v\u00e4lill\u00e4 ei kuitenkaan havaittu, mik\u00e4 viittaa siihen, ett\u00e4 \u00e4rsykeyhdistelmien v\u00e4lisi\u00e4 eroja ei kyetty havaitsemaan automaattisesti. Tulokset osoittavat, ett\u00e4 ik\u00e4\u00e4ntyneiden heikentynyt kyky\nsuodattaa pois ep\u00e4olennaisia \u00e4rsykkeit\u00e4 n\u00e4kyy my\u00f6s tilanteessa, jossa \u00e4rsykkeet muodostuvat kahden\neri aistij\u00e4rjestelm\u00e4n \u00e4rsykkeiden yhdistelmist\u00e4. On mahdollista, ett\u00e4 n\u00e4m\u00e4 aivojen toiminnan tasolla tapahtuvat muutokset vaikuttavat ik\u00e4\u00e4ntyneiden toimintakykyyn arjessa.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Event-related potentials (ERPs) reflecting early perceptual and cognitive functions are known to be \naffected by aging. In both auditory and somatosensory modalities, early responses to repetitive stimuli seem to be enhanced in amplitude in aged participants, indicating declined gating of irrelevant stimuli. On the other hand, later responses, such as the mismatch negativity (MMN), are attenuated compared\nto young adults. In the present study, the effects of aging on ERPs were investigated in a passive, crossmodal oddball condition, where frequent standard and infrequent deviant stimuli were presented. This stimulus condition was assumed to be effective in revealing aging-related decline in cognitive functions since it requires complex cognitive computations. The responses to auditory-somatosensory stimuli\nwere recorded from 44 aged (63-79 years) and 41 young (20-30 years) participants. The cross-modal stimuli elicited P50 and N1 responses in both age groups, the aged showing larger amplitudes for both responses. However, there were no differences between deviant and standard stimuli. Thus, no MMNs were elicited in either of the groups, suggesting that the cross-modal stimuli could not be differentiated automatically. The results indicate that insufficient sensory gating of multisensory stimuli is evident in aged. It is possible that these changes in brain level affect the functioning of the elderly in their\neveryday lives.", "language": "en", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted using Plone Publishing form by Miia Hakanen (mihakane) on 2016-03-02 09:49:38.841315. Form: Admin-lomake opinn\u00e4ytteiden julkaisuun (https://kirjasto.jyu.fi/julkaisut/julkaisulomakkeet/admin-lomake-opinnaytteet). JyX data: [jyx_publishing-allowed (fi) =False]", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by jyx lomake-julkaisija (jyx-julkaisija.group@korppi.jyu.fi) on 2016-03-02T09:49:39Z\nNo. of bitstreams: 2\nURN:NBN:fi:jyu-201603021742.pdf: 2710060 bytes, checksum: 5c4e1bfb3ded71b64508de112943e99a (MD5)\nlicense.html: 107 bytes, checksum: a7d86e598caa500b1b433bbb9dc8ef1c (MD5)", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2016-03-02T09:49:39Z (GMT). No. of bitstreams: 2\nURN:NBN:fi:jyu-201603021742.pdf: 2710060 bytes, checksum: 5c4e1bfb3ded71b64508de112943e99a (MD5)\nlicense.html: 107 bytes, checksum: a7d86e598caa500b1b433bbb9dc8ef1c (MD5)\n Previous issue date: 2015", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "1 verkkoaineisto (31 sivua)", "language": null, "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.format.mimetype", "value": "application/pdf", "language": null, "element": "format", "qualifier": "mimetype", "schema": "dc"}, {"key": "dc.language.iso", "value": "eng", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.subject.other", "value": "ik\u00e4\u00e4ntyminen", "language": null, "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "aivojen her\u00e4tevasteet", "language": null, "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "kuulo- ja tuntoaistimusten yhdist\u00e4minen", "language": null, "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "aistitiedon suodattaminen", "language": null, "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.title", "value": "Event-related potentials to cross-modal stimuli reveal altered sensory gating in aged", "language": null, "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", "value": "master thesis", "language": null, "element": "type", "qualifier": null, "schema": "dc"}, {"key": "dc.identifier.urn", "value": "URN:NBN:fi:jyu-201603021742", "language": null, "element": "identifier", "qualifier": "urn", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Pro gradu -tutkielma", "language": "fi", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Master\u2019s thesis", "language": "en", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Yhteiskuntatieteellinen tiedekunta", "language": "fi", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Faculty of Social Sciences", "language": "en", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Psykologian laitos", "language": "fi", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Department of Psychology", "language": "en", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "University of Jyv\u00e4skyl\u00e4", "language": "en", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "Jyv\u00e4skyl\u00e4n yliopisto", "language": "fi", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Psykologia", "language": "fi", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Psychology", "language": "en", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.date.updated", "value": "2016-03-02T09:49:40Z", "language": null, "element": "date", "qualifier": "updated", "schema": "dc"}, {"key": "yvv.contractresearch.funding", "value": "0", "language": null, "element": "contractresearch", "qualifier": "funding", "schema": "yvv"}, {"key": "dc.type.coar", "value": "http://purl.org/coar/resource_type/c_bdcc", "language": null, "element": "type", "qualifier": "coar", "schema": "dc"}, {"key": "dc.rights.accesslevel", "value": "restrictedAccess", "language": "fi", "element": "rights", "qualifier": "accesslevel", "schema": "dc"}, {"key": "dc.type.publication", "value": "masterThesis", "language": null, "element": "type", "qualifier": "publication", "schema": "dc"}, {"key": "dc.subject.oppiainekoodi", "value": "202", "language": null, "element": "subject", "qualifier": "oppiainekoodi", "schema": "dc"}, {"key": "dc.subject.yso", "value": "ik\u00e4\u00e4ntyminen", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "aivot", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "kuulo", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "tuntoaisti", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.format.content", "value": "fulltext", "language": null, "element": "format", "qualifier": "content", "schema": "dc"}, {"key": "dc.rights.url", "value": "https://rightsstatements.org/page/InC/1.0/", "language": null, "element": "rights", "qualifier": "url", "schema": "dc"}, {"key": "dc.rights.accessrights", "value": "Aineistoon p\u00e4\u00e4sy\u00e4 on rajoitettu tekij\u00e4noikeussyist\u00e4. Aineisto on luettavissa Jyv\u00e4skyl\u00e4n yliopiston kirjaston arkistoty\u00f6asemalta. Ks. https://kirjasto.jyu.fi/fi/tyoskentelytilat/laitteet-ja-tilat.", "language": "fi", "element": "rights", "qualifier": "accessrights", "schema": "dc"}, {"key": "dc.rights.accessrights", "value": "This material has a restricted access due to copyright reasons. It can be read at the workstation at Jyv\u00e4skyl\u00e4 University Library reserved for the use of archival materials: https://kirjasto.jyu.fi/en/workspaces/facilities.", "language": "en", "element": "rights", "qualifier": "accessrights", "schema": "dc"}, {"key": "dc.type.okm", "value": "G2", "language": null, "element": "type", "qualifier": "okm", "schema": "dc"}]
id jyx.123456789_48990
language eng
last_indexed 2025-03-31T20:03:38Z
main_date 2015-01-01T00:00:00Z
main_date_str 2015
publishDate 2015
record_format qdc
source_str_mv jyx
spellingShingle Pentikäinen, Emmi Event-related potentials to cross-modal stimuli reveal altered sensory gating in aged ikääntyminen aivojen herätevasteet kuulo- ja tuntoaistimusten yhdistäminen aistitiedon suodattaminen Psykologia Psychology 202 aivot kuulo tuntoaisti
title Event-related potentials to cross-modal stimuli reveal altered sensory gating in aged
title_full Event-related potentials to cross-modal stimuli reveal altered sensory gating in aged
title_fullStr Event-related potentials to cross-modal stimuli reveal altered sensory gating in aged Event-related potentials to cross-modal stimuli reveal altered sensory gating in aged
title_full_unstemmed Event-related potentials to cross-modal stimuli reveal altered sensory gating in aged Event-related potentials to cross-modal stimuli reveal altered sensory gating in aged
title_short Event-related potentials to cross-modal stimuli reveal altered sensory gating in aged
title_sort event related potentials to cross modal stimuli reveal altered sensory gating in aged
title_txtP Event-related potentials to cross-modal stimuli reveal altered sensory gating in aged
topic ikääntyminen aivojen herätevasteet kuulo- ja tuntoaistimusten yhdistäminen aistitiedon suodattaminen Psykologia Psychology 202 aivot kuulo tuntoaisti
topic_facet 202 Psychology Psykologia aistitiedon suodattaminen aivojen herätevasteet aivot ikääntyminen kuulo kuulo- ja tuntoaistimusten yhdistäminen tuntoaisti
url https://jyx.jyu.fi/handle/123456789/48990 http://www.urn.fi/URN:NBN:fi:jyu-201603021742
work_keys_str_mv AT pentikäinenemmi eventrelatedpotentialstocrossmodalstimulirevealalteredsensorygatinginaged