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Kati Korhonen (2015). Seerumin D-vitamiinipitoisuuden yhteys tasapainon varmuuteen, tasapainoon, liikkumiskykyyn ja kaatumisiin lonkkamurtumasta toipuvilla henkilöillä. Terveystieteiden laitos, Jyväskylän yliopisto, gerontologian ja kansanterveyden pro gradu-tutkielma, 47 s.
Lonkkamurtuma on yleisin iäkkäille henkilöille tapahtuva vakava tapaturma. Lonkkamurtu-mapotilailla on usein matala seerumin D-vitamiinipitoisuus, jonka on todettu olevan kaatumisen riskitekijä. Tämän tutkielman tarkoituksena oli selvittää, onko seerumin D-vitamiinipitoisuus yhteydessä tasapainon varmuuteen, tasapainoon, liikkumiskykyyn ja kaatumisiin lonkkamurtumasta toipuvilla henkilöillä.
Tutkielmassa käytettiin Promotion of mobility after hip fracture (ProMo)-kokeellisen tutkimuksen aineistoa. D-vitamiinin ja vastemuuttujien välisiä yhteyksiä tarkasteltiin sekä poikkileikkaus- että pitkittäisasetelmissa. Pitkittäisanalyysiä varten ProMo -tutkimuksen koe- ja kontrolliryhmät yhdistettiin. Tämän tutkielman aineiston muodostavat ne 68 kotona asuvaa yli 60-vuotiasta lonkkamurtumasta toipuvaa miestä (n=14) ja naista (n=54), joiden seerumin D-vitamiinipitoisuus oli määritetty. D-vitamiinipitoisuus mitattiin alkumittausten yhteydessä, keskimäärin 9 viikkoa murtuman jälkeen. Tasapainon varmuutta mitattiin koetun tasapainon varmuus (ABC) -testillä, tasapainoa Bergin tasapainotestillä (BBS), liikkumiskykyä Timed Up and Go (TUG)-testillä ja lyhyellä fyysisen suorituskyvyn testistöllä (SPPB) keskimäärin 9 viikkoa murtuman jälkeen ja vuoden kuluttua murtumasta. Kaatumisten lukumäärä murtumaa edeltävän vuoden ajalta selvitettiin kyselylomakkeella. D-vitamiinin yhteyttä muuttujiin selvitettiin lineaarisella regressioanalyysilla.
Miehillä D-vitamiinipitoisuus oli yhteydessä tasapainon varmuuteen (ABC β=.725, p=.003), tasapainoon (BBS β=.647, p=.012) ja liikkumiskykyä kuvaavaan TUG-testiin (TUG β=-.592, p=.026), mutta ei SPPB-testiin (SPPB β=.414, p=.141) poikkileikkausanalyysissa. Kun mallit vakioitiin iällä ja rasvaprosentilla, miehillä yhteydet säilyivät vahvoina, mutta eivät tilastollisesti merkitsevinä (ABC β=728, p=.064; BBS β=.328, p=.147; TUG β=-.428, p=.291; SPPB β=.078, p=131). Pitkittäisanalyysissa D-vitamiinipitoisuus oli miehillä yhteydessä tasapainon varmuuteen (ABC β=.843, p=<.001), tasapainoon (BBS β=.724, p=.012) ja SPPB-testiin (SPPB β=.610, p=.027), mutta ei TUG-testiin (TUG β=-.567, p=.088). Kun mallit vakioitiin tutkimusryhmällä, iällä ja rasvaprosentilla, tasapainon varmuus säilyi edelleen tilastollisesti merkitsevänä (β=1.030, p=.008). Naisilla yhteyttä ei havaittu. D-vitamiinipitoisuus ei ollut yhteydessä murtumaa edeltävän vuoden aikana tapahtuneiden kaatumisten lukumäärään.
Tämän tutkielman perusteella lonkkamurtumasta toipuvien miesten D-vitamiinipitoisuus näyttäisi olevan yhteydessä tasapainon varmuuteen, tasapainoon ja liikkumiskykyyn. Lisäksi miehillä, joilla oli korkeampi D-vitamiinipitoisuus lonkkamurtuman tapahtuessa, oli parempi tasapainon varmuus vuoden seurannassa. D-vitamiinipitoisuus ei ollut yhteydessä kaatumisiin sisä- tai ulkotiloissa murtumaa edeltävän vuoden aikana.
Kati Korhonen (2015). Association between Vitamin D-concentration, balance confidence, balance, mobility and falls in elderly people after hip fracture. Department of Health Sciences, University of Jyväskylä, Master’s Thesis of Gerontology and Public Health, 47 pp.
Hip fracture is the most common serious trauma that happens to the elderly people. Patients with hip fracture had often low vitamin D-concentration, which is risk factor for falls. Aim of this thesis was to examine the association between Vitamin D-concentration, balance confi-dence, balance, mobility and falls in elderly people after hip fracture.
This study was based on the data of RCT called Promotion of mobility after hip fracture (ProMo). Association between Vitamin D-concentration and outcome variables was examined with cross-sectional and longitudinal analyses. Intervention and control groups were combined for the longitudinal analyses. The data of this thesis was formed of those 68 community-dwelling over 60-year-old men and women recovering from hip fracture, whose Vitamin D-concentration was assessed. Vitamin D-concentration was measured at baseline, on average 9 weeks after fracture. Participant’s balance confidence was measured with Activities-specific Balance Confidence-test (ABC), balance with Berg’s balance scale (BBS), mobility with both Timed Up and Go-test (TUG) and Short Physical Performance Battery (SPPB) on average 9 weeks after fracture and and year after fracture. A questionnaire was used to assess falls of the previous year before the hip fracture. Association between Vitamin D-concentration and variables was analyzed with linear regression analyses.
Vitamin D-concentration was associated with balance confidence (β=.725, p=.003), balance (β=.647, p=.012) and TUG-test (β=-.592, p=.026), but not with SPPB (β=.414, p=.141) at baseline with men, but not with women. After adjustment for age and body fat percentage association remained strong, but statistically insignificant (ABC β=728, p=.064; BBS β=.328, p=.147; TUG β=-.428, p=.291; SPPB β=.078, p=131). Longitudinal analyses showed associa-tion between Vitamin D-concentration and balance confidence (β=.843, p=<.001), balance (β=.724, p=.012) and SPPB (β=.610, p=.027), but not with TUG-test (β=-.567, p=.088) with men, but not with women. After adjustment for study group, age and body fat percentage, balance confidence remained statistically significant (β=1.030, p=.008). Vitamin D-concentration was not associated with falls.
Vitamin D-concentration was associated with balance confidence, balance and mobility with men, but not with women after hip fracture. In addition, men with higher Vitamin D-concentration had higher balance confidence after a year follow-up. Vitamin D-concentration was not associated with falls.
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[{"key": "dc.contributor.advisor", "value": "Sipil\u00e4, Sarianna", "language": null, "element": "contributor", "qualifier": "advisor", "schema": "dc"}, {"key": "dc.contributor.author", "value": "Korhonen, Kati", "language": null, "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2015-11-12T19:16:09Z", "language": null, "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2015-11-12T19:16:09Z", "language": null, "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2015", "language": null, "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.other", "value": "oai:jykdok.linneanet.fi:1503970", "language": null, "element": "identifier", "qualifier": "other", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/47660", "language": null, "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Kati Korhonen (2015). Seerumin D-vitamiinipitoisuuden yhteys tasapainon varmuuteen, tasapainoon, liikkumiskykyyn ja kaatumisiin lonkkamurtumasta toipuvilla henkil\u00f6ill\u00e4. Terveystieteiden laitos, Jyv\u00e4skyl\u00e4n yliopisto, gerontologian ja kansanterveyden pro gradu-tutkielma, 47 s.\n\nLonkkamurtuma on yleisin i\u00e4kk\u00e4ille henkil\u00f6ille tapahtuva vakava tapaturma. Lonkkamurtu-mapotilailla on usein matala seerumin D-vitamiinipitoisuus, jonka on todettu olevan kaatumisen riskitekij\u00e4. T\u00e4m\u00e4n tutkielman tarkoituksena oli selvitt\u00e4\u00e4, onko seerumin D-vitamiinipitoisuus yhteydess\u00e4 tasapainon varmuuteen, tasapainoon, liikkumiskykyyn ja kaatumisiin lonkkamurtumasta toipuvilla henkil\u00f6ill\u00e4.\n\nTutkielmassa k\u00e4ytettiin Promotion of mobility after hip fracture (ProMo)-kokeellisen tutkimuksen aineistoa. D-vitamiinin ja vastemuuttujien v\u00e4lisi\u00e4 yhteyksi\u00e4 tarkasteltiin sek\u00e4 poikkileikkaus- ett\u00e4 pitkitt\u00e4isasetelmissa. Pitkitt\u00e4isanalyysi\u00e4 varten ProMo -tutkimuksen koe- ja kontrolliryhm\u00e4t yhdistettiin. T\u00e4m\u00e4n tutkielman aineiston muodostavat ne 68 kotona asuvaa yli 60-vuotiasta lonkkamurtumasta toipuvaa miest\u00e4 (n=14) ja naista (n=54), joiden seerumin D-vitamiinipitoisuus oli m\u00e4\u00e4ritetty. D-vitamiinipitoisuus mitattiin alkumittausten yhteydess\u00e4, keskim\u00e4\u00e4rin 9 viikkoa murtuman j\u00e4lkeen. Tasapainon varmuutta mitattiin koetun tasapainon varmuus (ABC) -testill\u00e4, tasapainoa Bergin tasapainotestill\u00e4 (BBS), liikkumiskyky\u00e4 Timed Up and Go (TUG)-testill\u00e4 ja lyhyell\u00e4 fyysisen suorituskyvyn testist\u00f6ll\u00e4 (SPPB) keskim\u00e4\u00e4rin 9 viikkoa murtuman j\u00e4lkeen ja vuoden kuluttua murtumasta. Kaatumisten lukum\u00e4\u00e4r\u00e4 murtumaa edelt\u00e4v\u00e4n vuoden ajalta selvitettiin kyselylomakkeella. D-vitamiinin yhteytt\u00e4 muuttujiin selvitettiin lineaarisella regressioanalyysilla.\n\nMiehill\u00e4 D-vitamiinipitoisuus oli yhteydess\u00e4 tasapainon varmuuteen (ABC \u03b2=.725, p=.003), tasapainoon (BBS \u03b2=.647, p=.012) ja liikkumiskyky\u00e4 kuvaavaan TUG-testiin (TUG \u03b2=-.592, p=.026), mutta ei SPPB-testiin (SPPB \u03b2=.414, p=.141) poikkileikkausanalyysissa. Kun mallit vakioitiin i\u00e4ll\u00e4 ja rasvaprosentilla, miehill\u00e4 yhteydet s\u00e4ilyiv\u00e4t vahvoina, mutta eiv\u00e4t tilastollisesti merkitsevin\u00e4 (ABC \u03b2=728, p=.064; BBS \u03b2=.328, p=.147; TUG \u03b2=-.428, p=.291; SPPB \u03b2=.078, p=131). Pitkitt\u00e4isanalyysissa D-vitamiinipitoisuus oli miehill\u00e4 yhteydess\u00e4 tasapainon varmuuteen (ABC \u03b2=.843, p=<.001), tasapainoon (BBS \u03b2=.724, p=.012) ja SPPB-testiin (SPPB \u03b2=.610, p=.027), mutta ei TUG-testiin (TUG \u03b2=-.567, p=.088). Kun mallit vakioitiin tutkimusryhm\u00e4ll\u00e4, i\u00e4ll\u00e4 ja rasvaprosentilla, tasapainon varmuus s\u00e4ilyi edelleen tilastollisesti merkitsev\u00e4n\u00e4 (\u03b2=1.030, p=.008). Naisilla yhteytt\u00e4 ei havaittu. D-vitamiinipitoisuus ei ollut yhteydess\u00e4 murtumaa edelt\u00e4v\u00e4n vuoden aikana tapahtuneiden kaatumisten lukum\u00e4\u00e4r\u00e4\u00e4n. \n\nT\u00e4m\u00e4n tutkielman perusteella lonkkamurtumasta toipuvien miesten D-vitamiinipitoisuus n\u00e4ytt\u00e4isi olevan yhteydess\u00e4 tasapainon varmuuteen, tasapainoon ja liikkumiskykyyn. Lis\u00e4ksi miehill\u00e4, joilla oli korkeampi D-vitamiinipitoisuus lonkkamurtuman tapahtuessa, oli parempi tasapainon varmuus vuoden seurannassa. D-vitamiinipitoisuus ei ollut yhteydess\u00e4 kaatumisiin sis\u00e4- tai ulkotiloissa murtumaa edelt\u00e4v\u00e4n vuoden aikana.", "language": "fi", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Kati Korhonen (2015). Association between Vitamin D-concentration, balance confidence, balance, mobility and falls in elderly people after hip fracture. Department of Health Sciences, University of Jyv\u00e4skyl\u00e4, Master\u2019s Thesis of Gerontology and Public Health, 47 pp.\n\nHip fracture is the most common serious trauma that happens to the elderly people. Patients with hip fracture had often low vitamin D-concentration, which is risk factor for falls. Aim of this thesis was to examine the association between Vitamin D-concentration, balance confi-dence, balance, mobility and falls in elderly people after hip fracture.\n\nThis study was based on the data of RCT called Promotion of mobility after hip fracture (ProMo). Association between Vitamin D-concentration and outcome variables was examined with cross-sectional and longitudinal analyses. Intervention and control groups were combined for the longitudinal analyses. The data of this thesis was formed of those 68 community-dwelling over 60-year-old men and women recovering from hip fracture, whose Vitamin D-concentration was assessed. Vitamin D-concentration was measured at baseline, on average 9 weeks after fracture. Participant\u2019s balance confidence was measured with Activities-specific Balance Confidence-test (ABC), balance with Berg\u2019s balance scale (BBS), mobility with both Timed Up and Go-test (TUG) and Short Physical Performance Battery (SPPB) on average 9 weeks after fracture and and year after fracture. A questionnaire was used to assess falls of the previous year before the hip fracture. Association between Vitamin D-concentration and variables was analyzed with linear regression analyses.\n\nVitamin D-concentration was associated with balance confidence (\u03b2=.725, p=.003), balance (\u03b2=.647, p=.012) and TUG-test (\u03b2=-.592, p=.026), but not with SPPB (\u03b2=.414, p=.141) at baseline with men, but not with women. After adjustment for age and body fat percentage association remained strong, but statistically insignificant (ABC \u03b2=728, p=.064; BBS \u03b2=.328, p=.147; TUG \u03b2=-.428, p=.291; SPPB \u03b2=.078, p=131). Longitudinal analyses showed associa-tion between Vitamin D-concentration and balance confidence (\u03b2=.843, p=<.001), balance (\u03b2=.724, p=.012) and SPPB (\u03b2=.610, p=.027), but not with TUG-test (\u03b2=-.567, p=.088) with men, but not with women. After adjustment for study group, age and body fat percentage, balance confidence remained statistically significant (\u03b2=1.030, p=.008). Vitamin D-concentration was not associated with falls.\n\nVitamin D-concentration was associated with balance confidence, balance and mobility with men, but not with women after hip fracture. In addition, men with higher Vitamin D-concentration had higher balance confidence after a year follow-up. Vitamin D-concentration was not associated with falls.", "language": "en", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted using Plone Publishing form by Kati Korhonen (korhkaan) on 2015-11-12 19:16:08.827529. Form: Pro gradu -lomake (https://kirjasto.jyu.fi/julkaisut/julkaisulomakkeet/pro-gradu-lomake). 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