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[{"key": "dc.contributor.author", "value": "Nieminen, Anne", "language": null, "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2011-01-21T08:34:49Z", "language": null, "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2011-01-21T08:34:49Z", "language": null, "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2010", "language": null, "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.other", "value": "oai:jykdok.linneanet.fi:1147103", "language": null, "element": "identifier", "qualifier": "other", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/25814", "language": null, "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Antibioottiresistenssi luokitellaan ihmisen terveyden suurimmaksi uhaksi. Antibioottiresistenssi lis\u00e4\u00e4ntyy bakteeripopulaatiossa konjugatiivisen plasmidin sis\u00e4lt\u00e4vien bakteerien v\u00e4lityksell\u00e4 jopa eri bakteerilajien v\u00e4lill\u00e4. PRD1-virus infektoi N-, P- ja W-tyypin konjugatiivisia plasmideja kantavia bakteereja. T\u00e4m\u00e4n ty\u00f6n tarkoituksena oli selvitt\u00e4\u00e4, voisiko PRD1-viruksen avulla poistaa bakteeripopulaation vastustuskyky antibiooteille. T\u00e4t\u00e4 testattiin kasvattamalla antibiooteille vastustuskykyisi\u00e4 bakteereja ilman virusta ja viruksen l\u00e4sn\u00e4 ollessa. Bakteerien kasvuk\u00e4yr\u00e4t mitattiin lis\u00e4ksi eri kasvuymp\u00e4rist\u00f6iss\u00e4. Tulosten mukaan virus pudottaa populaation antibioottiresistenssin 100 %:sta jopa alle prosenttiin kymmeness\u00e4 p\u00e4iv\u00e4ss\u00e4. Bakteerien kasvattaminen sek\u00e4 antibiootti- ett\u00e4 virusymp\u00e4rist\u00f6ss\u00e4 muokkaa osasta bakteereja vastustuskykyisi\u00e4 molemmille. Tulosten perusteella voidaan siis ehdottaa PRD1-virusta avuksi taistelussa antibioottiresistenttej\u00e4 bakteereja vastaan. Viruksella voi olla potentiaalia tehostaa terveydenhoitoa ensiksi vaikuttavana hoitona, joka tuhoaa vastustuskykyisi\u00e4 bakteereja, jonka j\u00e4lkeen antibioottikuurilla taltutettaisiin j\u00e4ljelle j\u00e4\u00e4neet antibiooteille herk\u00e4t bakteerit. Mahdollisuutena on my\u00f6s k\u00e4ytt\u00e4\u00e4 viruksia tartuntojen ehk\u00e4isyss\u00e4.", "language": null, "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted using Plone Publishing form by Anne Nieminen (annmarni) on 2011-01-21 08:34:46.719651. Form: Pro gradu -lomake (1 tekij\u00e4) (https://kirjasto.jyu.fi/julkaisut/julkaisulomakkeet/pro-gradu-lomake-1-tekijae). JyX data:", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by jyx lomake-julkaisija (jyx-julkaisija@noreply.fi) on 2011-01-21T08:34:49Z\nNo. of bitstreams: 2\nURN:NBN:fi:jyu-201101211041.pdf: 486960 bytes, checksum: 4e41a67b5b510d883a8ed05761ca72bb (MD5)\nlicense.html: 5039 bytes, checksum: c6c2499053276c770d98219c1a0cf3cd (MD5)", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2011-01-21T08:34:49Z (GMT). No. of bitstreams: 2\nURN:NBN:fi:jyu-201101211041.pdf: 486960 bytes, checksum: 4e41a67b5b510d883a8ed05761ca72bb (MD5)\nlicense.html: 5039 bytes, checksum: c6c2499053276c770d98219c1a0cf3cd (MD5)\n Previous issue date: 2010", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "46 sivua", "language": null, "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.format.mimetype", "value": "application/pdf", "language": null, "element": "format", "qualifier": "mimetype", "schema": "dc"}, {"key": "dc.language.iso", "value": "fin", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.subject.other", "value": "PRD1", "language": null, "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.title", "value": "PRD1-viruksen vaikutus bakteerisoluihin, jotka sis\u00e4lt\u00e4v\u00e4t antibioottivastustuskyvyn antavan plasmidin", "language": null, "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", "value": "master thesis", "language": null, "element": "type", "qualifier": null, "schema": "dc"}, {"key": "dc.identifier.urn", "value": "URN:NBN:fi:jyu-201101211041", "language": null, "element": "identifier", "qualifier": "urn", "schema": "dc"}, {"key": "dc.type.dcmitype", "value": "Text", "language": "en", "element": "type", "qualifier": "dcmitype", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Pro gradu -tutkielma", "language": "fi", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Master\u2019s thesis", "language": "en", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Matemaattis-luonnontieteellinen tiedekunta", "language": "fi", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Faculty of Sciences", "language": "en", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Bio- ja ymp\u00e4rist\u00f6tieteiden laitos", "language": "fi", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Department of Biological and Environmental Science", "language": "en", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "University of Jyv\u00e4skyl\u00e4", "language": "en", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "Jyv\u00e4skyl\u00e4n yliopisto", "language": "fi", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Solu- ja molekyylibiologia", "language": "fi", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Cell and molecular biology", "language": "en", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.type.coar", "value": "http://purl.org/coar/resource_type/c_bdcc", "language": null, "element": "type", "qualifier": "coar", "schema": "dc"}, {"key": "dc.rights.accesslevel", "value": "openAccess", "language": "fi", "element": "rights", "qualifier": "accesslevel", "schema": "dc"}, {"key": "dc.type.publication", "value": "masterThesis", "language": null, "element": "type", "qualifier": "publication", "schema": "dc"}, {"key": "dc.subject.oppiainekoodi", "value": "4013", "language": null, "element": "subject", "qualifier": "oppiainekoodi", "schema": "dc"}, {"key": "dc.subject.yso", "value": "resistenssi", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "bakteerit", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "antibioottiresistenssi", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "plasmidit", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.format.content", "value": "fulltext", "language": null, "element": "format", "qualifier": "content", "schema": "dc"}, {"key": "dc.rights.url", "value": "https://rightsstatements.org/page/InC/1.0/", "language": null, "element": "rights", "qualifier": "url", "schema": "dc"}, {"key": "dc.type.okm", "value": "G2", "language": null, "element": "type", "qualifier": "okm", "schema": "dc"}]
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