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[{"key": "dc.contributor.author", "value": "Karvonen, Anu", "language": null, "element": "contributor", "qualifier": "author", "schema": "dc"}, {"key": "dc.date.accessioned", "value": "2010-12-16T20:05:23Z", "language": "", "element": "date", "qualifier": "accessioned", "schema": "dc"}, {"key": "dc.date.available", "value": "2010-12-16T20:05:23Z", "language": "", "element": "date", "qualifier": "available", "schema": "dc"}, {"key": "dc.date.issued", "value": "2010", "language": null, "element": "date", "qualifier": "issued", "schema": "dc"}, {"key": "dc.identifier.other", "value": "oai:jykdok.linneanet.fi:1144614", "language": null, "element": "identifier", "qualifier": "other", "schema": "dc"}, {"key": "dc.identifier.uri", "value": "https://jyx.jyu.fi/handle/123456789/25706", "language": "", "element": "identifier", "qualifier": "uri", "schema": "dc"}, {"key": "dc.description.abstract", "value": "Tutkimuksen tavoitteena oli luoda oskillatorista tahdistamista rotan kuuloaivokuorella sek\u00e4 valikoivasti h\u00e4irit\u00e4 sit\u00e4. Tahdistamista ei ole juuri lainkaan tutkittu aiemmin, joten tutkimuksessa yritettiin l\u00f6yt\u00e4\u00e4 uutta tietoa k\u00e4ytt\u00e4en ainutlaatuista kokeellista asetelmaa. Viisitoista rottaa nukutettiin uretaanilla ja niilt\u00e4 mitattiin paikallisia kentt\u00e4potentiaaleja (local field potentials,LFPs) kovakalvon p\u00e4\u00e4lle sijoitetun solun ulkopuolisen mikroelektrodin avulla. Nelj\u00e4ss\u00e4 p\u00e4\u00e4kokeessa luotiin 2,5 Hz tahdistamista yhdeks\u00e4n \u00e4rsykkeen \u00e4\u00e4nijonoilla, miss\u00e4 tahdistamis\u00e4\u00e4nen taajuus oli 4000 Hz ja h\u00e4iritsev\u00e4n \u00e4\u00e4nen taajuus oli 4500 Hz. H\u00e4irint\u00e4 oli aina kahdeksannessa \u00e4\u00e4ness\u00e4, jonka vaihetta ja/tai taajuutta muutettiin. Tutkimuksessa testattiin my\u00f6s tahdistamistaajuuden viiveen vaihtelua sek\u00e4 esitettiin yksitt\u00e4isten \u00e4\u00e4nien kokeita. Tulosten analysoinnissa huomioitiin se, ett\u00e4 rotta voi olla mittaamisen aikana joko niin sanotussa up & down tai kompleksissa tilassa, joista kompleksia tilaa tulisi suosia vasteiden eroavuuksien tarkastelussa.\r\n\r\nVaiheh\u00e4irinn\u00e4n tulokset osoittivat, ett\u00e4 vaiheen pident\u00e4misell\u00e4 on tietty ero verrattuna vaiheen lyhent\u00e4miseen. Pidemm\u00e4n vaiheen vaste muuttui negatiivisemmaksi kuin edelt\u00e4v\u00e4n tahdistavan \u00e4\u00e4nen vaste noin 62-124 ms kohdalla ja nousi positiivisemmaksi noin 168-224 ms kohdalla. Taajuush\u00e4irint\u00e4 puolestaan aiheutti positiivisempaa tasoa kuin edelt\u00e4v\u00e4n tahdistavan \u00e4\u00e4nen vasteella noin 86-138 ms kohdalla, mik\u00e4 osoittaa muutosten aikajanojen eroavan toisistaan. Kun vaihe- ja taajuush\u00e4irint\u00e4 yhdistettiin, sek\u00e4 pidempi ett\u00e4 lyhyempi vaiheh\u00e4irint\u00e4 olivat positiivisempia kuin edelt\u00e4v\u00e4n tahdistavan \u00e4\u00e4nen vaste noin 41-160 ms v\u00e4lill\u00e4. Pidempi vaihe aiheutti edelleen positiivisemman vasteen kuin lyhyempi vaihe erojen aikajanan ollessa noin 23-141 ms ja 252 ms eteenp\u00e4in. Taajuush\u00e4irinn\u00e4n vaste s\u00e4ilyi vaikka tahdistamistaajuudessa oli viiveen vaihtelua, mik\u00e4 osoittaa ett\u00e4 ei ole v\u00e4li\u00e4 onko tahdistamisessa aina tietty kiinte\u00e4 v\u00e4liaika vai vaihteleeko aika puolisatunnaisesti. T\u00e4rke\u00e4 tulos oli my\u00f6s se, ett\u00e4 alussa eri \u00e4\u00e4net eiv\u00e4t poikenneet toisistaan eiv\u00e4tk\u00e4 muuttuneet ensimm\u00e4isen yksitt\u00e4isten \u00e4\u00e4nien kokeen aikana. Eroja tuli vasta tahdistamiskokeen j\u00e4lkeen, jolloin h\u00e4iritsev\u00e4\u00e4n \u00e4\u00e4neen tuli positiivisempi vaste kuin tahdistavaan \u00e4\u00e4neen. N\u00e4iden tuloksien pohjalta ehdotetaan ett\u00e4 tahdistaminen voi luoda muistij\u00e4lki\u00e4 hermoj\u00e4rjestelm\u00e4\u00e4n, jopa niin ett\u00e4 j\u00e4lki voi olla vahvempi h\u00e4iritsev\u00e4lle \u00e4rsykkeelle.", "language": "", "element": "description", "qualifier": "abstract", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted using Plone Publishing form by Anu Karvonen (anjokarv) on 2010-12-16 20:05:20.444092. Form: Pro gradu -lomake (1 tekij\u00e4) (https://kirjasto.jyu.fi/julkaisut/julkaisulomakkeet/pro-gradu-lomake-1-tekijae). JyX data:", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Submitted by jyx lomake-julkaisija (jyx-julkaisija@noreply.fi) on 2010-12-16T20:05:23Z\r\nNo. of bitstreams: 2\r\nURN:NBN:fi:jyu-201012163187.pdf: 649236 bytes, checksum: c3ecb958aab4c6ca8a378017f8767a50 (MD5)\r\nlicense.html: 5035 bytes, checksum: 1833ab09669ccde7c4c9ab766ec2159a (MD5)", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.description.provenance", "value": "Made available in DSpace on 2010-12-16T20:05:23Z (GMT). No. of bitstreams: 2\r\nURN:NBN:fi:jyu-201012163187.pdf: 649236 bytes, checksum: c3ecb958aab4c6ca8a378017f8767a50 (MD5)\r\nlicense.html: 5035 bytes, checksum: 1833ab09669ccde7c4c9ab766ec2159a (MD5)\r\n Previous issue date: 2010", "language": "en", "element": "description", "qualifier": "provenance", "schema": "dc"}, {"key": "dc.format.extent", "value": "48 sivua", "language": null, "element": "format", "qualifier": "extent", "schema": "dc"}, {"key": "dc.format.mimetype", "value": "application/pdf", "language": null, "element": "format", "qualifier": "mimetype", "schema": "dc"}, {"key": "dc.language.iso", "value": "eng", "language": null, "element": "language", "qualifier": "iso", "schema": "dc"}, {"key": "dc.rights", "value": "In Copyright", "language": "en", "element": "rights", "qualifier": null, "schema": "dc"}, {"key": "dc.subject.other", "value": "paikalliset kentt\u00e4potentiaalit", "language": null, "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "kuuloaivokuori", "language": null, "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.subject.other", "value": "tahdistaminen", "language": null, "element": "subject", "qualifier": "other", "schema": "dc"}, {"key": "dc.title", "value": "Entrainment and its perturbation in the auditory cortex of the rat : phase and frequency modulations", "language": null, "element": "title", "qualifier": null, "schema": "dc"}, {"key": "dc.type", "value": "master thesis", "language": null, "element": "type", "qualifier": null, "schema": "dc"}, {"key": "dc.identifier.urn", "value": "URN:NBN:fi:jyu-201012163187", "language": null, "element": "identifier", "qualifier": "urn", "schema": "dc"}, {"key": "dc.type.dcmitype", "value": "Text", "language": "en", "element": "type", "qualifier": "dcmitype", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Pro gradu -tutkielma", "language": "fi", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.type.ontasot", "value": "Master\u2019s thesis", "language": "en", "element": "type", "qualifier": "ontasot", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Yhteiskuntatieteellinen tiedekunta", "language": "fi", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.faculty", "value": "Faculty of Social Sciences", "language": "en", "element": "contributor", "qualifier": "faculty", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Psykologian laitos", "language": "fi", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.department", "value": "Department of Psychology", "language": "en", "element": "contributor", "qualifier": "department", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "University of Jyv\u00e4skyl\u00e4", "language": "en", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.contributor.organization", "value": "Jyv\u00e4skyl\u00e4n yliopisto", "language": "fi", "element": "contributor", "qualifier": "organization", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Psykologia", "language": "fi", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.subject.discipline", "value": "Psychology", "language": "en", "element": "subject", "qualifier": "discipline", "schema": "dc"}, {"key": "dc.type.coar", "value": "http://purl.org/coar/resource_type/c_bdcc", "language": null, "element": "type", "qualifier": "coar", "schema": "dc"}, {"key": "dc.rights.accesslevel", "value": "openAccess", "language": "fi", "element": "rights", "qualifier": "accesslevel", "schema": "dc"}, {"key": "dc.type.publication", "value": "masterThesis", "language": null, "element": "type", "qualifier": "publication", "schema": "dc"}, {"key": "dc.subject.oppiainekoodi", "value": "202", "language": null, "element": "subject", "qualifier": "oppiainekoodi", "schema": "dc"}, {"key": "dc.subject.yso", "value": "h\u00e4irint\u00e4", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "kuulo", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.subject.yso", "value": "rotat", "language": null, "element": "subject", "qualifier": "yso", "schema": "dc"}, {"key": "dc.format.content", "value": "fulltext", "language": null, "element": "format", "qualifier": "content", "schema": "dc"}, {"key": "dc.rights.url", "value": "https://rightsstatements.org/page/InC/1.0/", "language": null, "element": "rights", "qualifier": "url", "schema": "dc"}, {"key": "dc.type.okm", "value": "G2", "language": null, "element": "type", "qualifier": "okm", "schema": "dc"}]
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